RetrogeneDB ID: retro_ggor_58

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 8:143834747..143836358(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000005440
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSGGOG00000010581
• Aliases: None
• Description: None

Sequence

>retro_ggor_58
ATGATTTTGTTGTCTTTTGTTTCAGATTCTAATGTAGGAACTGGTGAGAAGAAGGTGACTGAAGCCTGGATTTCTGAGGA
TGAAAATTCACATAGGACGACGTCAGACAGACTCACGGTGATGGAGCTCCCCTCTCCCGAGTCTGAGGAAGTCCACGAGC
CCAGATTAGGGGAGCTCTTGGGAAATCCAGAAGGTCAGAGCCTGGGGAGTTCCCCCTCTCAGGACAGGGGCTGCAAGCAG
GTGACAGTGACCCATTGGAAGATCCAGACAGGAGAGACAGCTCAAGTGTGCACCAAGTCAGGAAGAAACCGTATTCTGAA
CTCAGACCTTCTTCTGCTTCAGAGAGAGCTCATAGAGGGGGAAGCCAATCCTTGCGATATCTGTGGCAAAACCTTCACGT
TTAATTCGGACCTAGTTAGGCATCGGATTTCGCATGCTGGGGAGAAACCTTACACGTGCGATCAGTGTGGGAAAGGCTTT
GGCCAGAGCTCACACCTTATGGAGCATCAGAGAATTCACACTGGAGAGAGACTCTACGTCTGTAATGTGTGTGGGAAAGA
TTTCATTCACTATTCAGGTCTCATTGAGCATCAGCGCGTTCATTCAGGAGAAAAGCCCTTCAAATGTGCGCAGTGTGGGA
AGGCGTTTTGTCACAGTTCAGACCTGATTAGGCACCAGAGAGTTCACACCAGAGAGAGACCTTTTGAATGCAAAGAGTGT
GGGAAAGGCTTCAGTCAGAGCTCCTTACTTATTCGCCATCAGAGGATTCACACGGGAGAAAGGCCCTATGAGTGCAATGA
ATGTGGGAAATCCTTCATAAGGAGCTCGAGCCTCATTCGCCACTATCAGATCCACACAGAAGTGAAACAGTATGAATGCA
AAGAATGTGGGAAGGCATTCCGTCATCGCTCAGACCTTATTGAACACCAGAGAATTCACACCGGAGAGAGACCCTTTGAA
TGCAATGAGTGTGGGAAAGCCTTTATTCGGAGTTCAAAGCTCATTCAGCATCAGAGGATCCATACTGGGGAGAGGCCTTA
CGTATGCAATGAGTGTGGGAAGCGCTTCAGCCAGACGTCAAACTTCACCCAGCATCAGAGGATTCACACTGGAGAGAAAC
TCTATGAATGTAACGAGTGTGGGAAAGCTTTCTTTCTGAGTTCATACCTTATTCGACACCAGAAAATCCACACTGGAGAG
AGAGTGTATGAATGTAAGGAATGTGGGAAAGCGTTTCTCCAGAAAGCCCATCTCACCGAGCACCAGAAGATCCACTCTGG
GGACAGGCCCTTCGAATGTAAAGACTGTGGGAAGGCCTTCATCCAGAGCTCCAAGCTGCTTCTGCACCAGATTATTCACA
CTGGAGAAAAGCCCTATGTGTGCAGTTATTGTGGGAAGGGCTTTATTCAGAGGTCAAACTTCCTTCAACACCAGAAAATT
CATAGTGAAGAGAAGCTCTATGAATGTAGTCAGTATGGGAGAGATTTTAACCCAACTACAAACTTTAAAAATAATCAAAG
TGTTCACCAAGAGGGACTCTCCTTGAGTAAGGCCCCCATACATTTGGGTGAGAGGTCTGTAGATAAGGGGGAACACACAG
GTAACTTATAA

Alignment

ORF - retro_ggor_58 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 54.22 %
• Parental protein coverage: 79.5 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  CTECGKAFIYHLDYILHQRIHTGEKPYRCRDCGKAFSNSSYFIQHHHQRIHTGEKPYKCKDCGKAFTQSS
          CT..G...I...D..L.QR.........C..CGK.F...S....H.....H.GEKPY.C..CGK.F.QSS
Retrocopy CTKSGRNRILNSDLLLLQRELIEGEANPCDICGKTFTFNSDLVRHRIS--HAGEKPYTCDQCGKGFGQSS

Parental  SLIKHQQCHTGEKPYKCGQCGKFYSQVSHLTRHQKIHTGEKPYQCGECGKAFCHTSSLTQHQTTHTGEKP
          .L..HQ..HTGE..Y.C..CGK.....S.L..HQ..H.GEKP..C..CGKAFCH.S.L..HQ..HT.E.P
Retrocopy HLMEHQRIHTGERLYVCNVCGKDFIHYSGLIEHQRVHSGEKPFKCAQCGKAFCHSSDLIRHQRVHTRERP

Parental  YKCNKCGKTFSHSSSLTEHQRVHTGEKPYECTDCGKAFSHSSPLTQHQRIHTGEKPCMCHECRKAYTQIS
          ..C..CGK.FS.SS.L..HQR.HTGE.PYEC..CGK.F..SS.L..H..IHT..K...C.EC.KA....S
Retrocopy FECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKSFIRSSSLIRHYQIHTEVKQYECKECGKAFRHRS

Parental  HLMRHQSTHVGEKPYICNECGKAFSHTSSFTQHQTIHTGEKPYKCTECGKTFSQNSSFTRHQRIHTGEKS
          .L..HQ..H.GE.P..CNECGKAF...S...QHQ.IHTGE.PY.C.ECGK.FSQ.S.FT.HQRIHTGEK.
Retrocopy DLIEHQRIHTGERPFECNECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKL

Parental  YECKVCGKACTQISHLIQHQRIHTGERPYQCSECGKDFSRSTHLIEHQKIHTGEKPYKCKECGKTFSHNS
          YEC..CGKA....S.LI.HQ.IHTGER.Y.C.ECGK.F....HL.EHQKIH.G..P..CK.CGK.F...S
Retrocopy YECNECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHSGDRPFECKDCGKAFIQSS

Parental  SLAQHQRIHTGEKPYACKECGKAFNQSIHLIQHQRIHTEEKPYKCSDCGRTYTQISHLLQHQKVH
          .L..HQ.IHTGEKPY.C..CGK.F.Q.....QHQ.IH.EEK.Y.CS..GR...........Q.VH
Retrocopy KLLLHQIIHTGEKPYVCSYCGKGFIQRSNFLQHQKIHSEEKLYECSQYGRDFNPTTNFKNNQSVH

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	17.22 RPM	0.05 RPM
SRP007412_cerebellum	15.40 RPM	0.08 RPM
SRP007412_heart	2.91 RPM	0.00 RPM
SRP007412_kidney	8.30 RPM	0.08 RPM
SRP007412_liver	4.46 RPM	0.03 RPM
SRP007412_testis	11.50 RPM	0.31 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_58 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_58 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 1 parental gene, and 1 retrocopy.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000010581	1 retrocopy	retro_ggor_58 ,