RetrogeneDB ID: retro_ggor_709

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 11:50159658..50160621(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000028601
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: SLC25A33
• Ensembl ID: ENSGGOG00000006766
• Aliases: None
• Description: None

Sequence

>retro_ggor_709
ATGGCGACGGGCGGCCAGCAGAAGGCGAACACGCTGCTTCACCTCTTCGCCGGCGGGTGTGGAGGCACAGTTGGTGCTAT
TTTCACTTGTCCACTAGAAGTCATTAAGACACGGTTGCAGTCTTCAAGATTAGCTCTCCGGACAGTCTACTATCCTCAGG
TTCATCTGGGGACCATTAGTGGAGCTGGAATGGTGAGACCAACATCTGTGACACCTGGACTCTTTCAGGTTCTGAAGTCG
ATCTTGGAGAAAGAGGGACCAAAGTCACTTTTTAGAGGCTTGGGTCCAAATTTGATTGGAGTTGCACCATCAAGGGCTGT
ATATTTTGCATGTTACTCCAAAGCCAAAGAGCAATTTAATGGCATTTTCGTGCCTAACAGCAATATTGTGCATATTTTCT
CAGCTGGCTCTGCAGCTTTTATCACAAATTCCTTAATGAATCCTATATGGATGGTTAAAACCCGAATGCAGCTAGAACAG
AAAGTGAGGGGCTCTAAGCAGATGAATACACTCCAGTGTGCTCGTTACGTTTACCAGACCAAAGGCATTCGTGGCTTCTA
TAGAGGATTAACTGCCTCGTATGCTGGAATTTCCGAAACTATAATCTGCTTTGCTATTTATGAAAGTTTAAAGAAGTATC
TGAAAGAAGCTCCATTAGCCTCTTCTGCAAATGGGACTGAGAAAAATTCCACAAGTTTTTTTGGACTTATGGCAGCTGCT
GCTCTTTCTAAGGGCTGTGCCTCCTGCATTGCTTATCCACACGAAGTTATAAGGACGAGGCTCCGGGAAGAGGGCACCAA
GTACAAGTCTTTTGTCCAGACGGCGCACCTGGTGTTCCGGGAAGAAGGCTACCTCGCCTTTTATAGAGGACTGTTTGCCC
AGCTTATCCGGCAGATCCCAAATACTGCCATTGTGTTGTCTACCTATGAGTTAATTGTGTACCTGTTAGAAGACCGTACT
CAG

Alignment

ORF - retro_ggor_709 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 95.64 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MATGGQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMIRSFTV
          MATGGQQK.NTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGM.R...V
Retrocopy MATGGQQKANTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTISGAGMVRPTSV

Parental  FVGFLFVLLSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAF
          ..G...VL.SILEKEGPKSLFRGLGPNL.GVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAF
Retrocopy TPGLFQVLKSILEKEGPKSLFRGLGPNLIGVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAF

Parental  ITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASYAGISETIICFAIYESL
          ITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQT.GIRGFYRGLTASYAGISETIICFAIYESL
Retrocopy ITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQTKGIRGFYRGLTASYAGISETIICFAIYESL

Parental  KKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFR
          KKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTA.LVFR
Retrocopy KKYLKEAPLASSANGTEKNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTAHLVFR

Parental  EEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLLEDRTQ
          EEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLLEDRTQ
Retrocopy EEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLLEDRTQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	1.15 RPM	7.29 RPM
SRP007412_cerebellum	1.02 RPM	4.92 RPM
SRP007412_heart	0.41 RPM	1.13 RPM
SRP007412_kidney	1.06 RPM	5.81 RPM
SRP007412_liver	0.21 RPM	4.09 RPM
SRP007412_testis	15.85 RPM	17.82 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_709 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_709 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 6 parental genes, and 6 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000000424	1 retrocopy	retro_cjac_2186,
Dasypus novemcinctus	ENSDNOG00000014396	1 retrocopy	retro_dnov_2369,
Homo sapiens	ENSG00000171612	1 retrocopy	retro_hsap_873,
Gorilla gorilla	ENSGGOG00000006766	1 retrocopy	retro_ggor_709 ,
Monodelphis domestica	ENSMODG00000003059	1 retrocopy	retro_mdom_1512,
Otolemur garnettii	ENSOGAG00000007103	1 retrocopy	retro_ogar_2098,