RetrogeneDB ID: retro_ggor_90

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 20:20925775..20926840(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000027642
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: INSM2
• Ensembl ID: ENSGGOG00000008351
• Aliases: None
• Description: None

Sequence

>retro_ggor_90
GGCGCCCCGCTGCTCTTCGCGCCCGCCGAGCTCAAGATGGGCACGGCGTTCTCGACTGGCGCCGAGGCGGCCCGCGGCCC
GGGGCCCGGCCCCCCACTGCCCCCTGCCGCCGCCCTGCGGCCCCCGGGAAAGCGGCCCCCGCCCCCCACCGCAGCGGAGC
CGCCCGCCAAGGCAGTCAAGGCCCCGGGCGCCAAGAAGCCCAAGGCCATCCGCAAGCTGCACTTCGAGGACGAGGTGACC
ACGTCGCCCGTGCTGGGGCTCAAGATCAAGGAGGGCCCGGTGGAGGCGCCGCGGGGTCGCGCGGGGGGCGCGGCGCGGCC
GCTCGGCGAGTTCATCTGCCAGCTGTGCAAGGAGGAGTACGCCGACCCGTTCGCGCTGGCGCAGCACAAATGCTCGCGCA
TCGTGCGTGTGGAGTACCGCTGTCCCGAGTGCGCCAAGGTCTTCAGCTGCCCGGCCAACCTGGCCTCGCACCGCCGCTGG
CACAAACCGCGGCCCGCGCCCGCCGCCGCCCGCGCGCCGGAGCCGGAAGCAGCAGCCAGGGCTGAGGCGCGGGAGGCACC
CGCCGGCGGTAGCGACCGGGACACGCCGAGTCCCGGCGGCGTATCCGAGTCGGGCTCCGAGGACGGGCTCTACGAGTGCC
ATCACTGCGCCAAGAAGTTCCGCCGCCAGGCCTACCTACGCAAGCACCTGCTGGCGCACCACCAGGCGCTGCAGGCCAAG
GGCGCGCCGCCAGCGCCCCCGGCCGAGGACCTACTGGCCTTGTACCCTGGGCCCGACGAGAAGGCGCCCCAGGAGGCGAC
CGGCGACGGCGAGGCGGCCGGCGTGCTGGGCCTGAGTGCGTCCGCCGAGTGCCACCTGTGCCCAGTGTGCGGAGAGTCGT
TCGCCAGCAAGGGCGCCCAGGAGCGCCACCTGCGCCTGCTGCACGCCGCCCAGGTGTTCCCCTGCAAGTACTGCCCGGCC
ACCTTCTACAGCTCGCCCGGCCTTACGCGGCACATCAACAAGTGCCACCCATCCGAAAACAGACAGGTGATCCTCCTGCA
GGTGCCCGTGCGCCCGGCCTGCTAG

Alignment

ORF - retro_ggor_90 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 58.46 %
• Parental protein coverage: 66.23 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  PPLSAALQSLKRAPAASAAGLRVPA--AAGIKKPKAMRKLSFADEVTTSPVLGLKIKEGP--APSRGLGG
          PP..A.....KR.P...AA.....A..A.G.KKPKA.RKL.F.DEVTTSPVLGLKIKEGP..AP....GG
Retrocopy PPAAALRPPGKRPPPPTAAEPPAKAVKAPGAKKPKAIRKLHFEDEVTTSPVLGLKIKEGPVEAPRGRAGG

Parental  AA-PLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAART
          AA.PLGEFICQLCKE.YADPFALAQH.CSRIVRVEYRCPEC.KVFSCPANLASHRRWHKPRPA.A.AAR.
Retrocopy AARPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPAPA-AARA

Parental  PGPGSAARDSSGARTAPRGRASRCRIQSHRCVPVPGAGDEIFVCPYCHKKFRRQAYLRKH--EHHEAARP
          P.P..AAR....AR.AP.G...R....S...V...G..D....C..C.KKFRRQAYLRKH...HH.A...
Retrocopy PEPEAAAR--AEAREAPAGGSDR-DTPSPGGVSESGSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQA

Parental  VLAP--PNAAPLARL---PIVRAHQQISGRSTGCGML----SARSCSCPLWRGLLPKRRALAGH---LSA
          ..AP..P.A..L..L...P...A.Q...G.....G.L....SA....CP..........A...H...L.A
Retrocopy KGAPPAPPAEDLLALYPGPDEKAPQEATGDGEAAGVLGLSASAECHLCPVCGESFASKGAQERHLRLLHA

Parental  QQIFSCKHCPSTFFSSPGLTRHINKCHPSESRQVLLLQMPLRPGC
          .Q.F.CK.CP.TF.SSPGLTRHINKCHPSE.RQV.LLQ.P.RP.C
Retrocopy AQVFPCKYCPATFYSSPGLTRHINKCHPSENRQVILLQVPVRPAC

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	1.34 RPM	1.15 RPM
SRP007412_cerebellum	5.91 RPM	0.08 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.21 RPM	0.10 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_90 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_90 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 1 parental gene, and 1 retrocopy.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000008351	1 retrocopy	retro_ggor_90 ,