RetrogeneDB ID: retro_ggor_947

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 13:59719040..59722433(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: DHX9
• Ensembl ID: ENSGGOG00000013533
• Aliases: None
• Description: None

Sequence

>retro_ggor_947
TCCTGGGACCAAGGAGCCAACTTGAAGGATTACTACTCAAGAAAGGAAGAACAAGAAGTGCAAGTTAATCTAGAGTCAGA
AGAAGTGGATTTAAATGCTGGGCTTCATGGAAACTGGACCTCGGAAAATGCTAAAACTCATCTAAACCAATATTTTCAGA
AAGAAAAAATCCAAGGAGAATATGAGTACACCCAAGTGGGTCCTGATCACAACAGGAGCTTTACTGCAGAAATAACCGTT
TACATCAAGCAGCTGGGCAGAAGGATTTTTGCACATGAACATGGATCAAATAAGAAATTGGCAGCACAGTCCTGTGCCAT
GTCACTAGTCAGACAACTCTACCATCTTGGAGTGGTTGAAGCTTACTTCGGACTTACAAAGAAGGAAGGAGAGAGAGTGG
AACCTTACAAAGTAAACCTCTCTCGTGATTTACAGCATCAGCCACAAAACATCATTTGAGAGCTAAATCTTGAGATTATG
CCCCCGCCTGAAGATCCTTCTATGCCAGTTGCACTCAACATTGGCAAATTGGCTCACTTTGAACCATCTCGGTGACAAAA
CCAAGTGGGTATAGTTCCTCGGTCACCTCCACAATCCAGATGGAATCCTTGGACTACTAGCAACATTGCTGAGGGACCTC
TGGCTTTTGCTTCTCCAGAGCAAATAAGCTTGGACCTCAAGAATGAATTGGTGTACCAGTTGGAACAGGATCATGATTTG
CCAGCAATCTTGCAGGAGCAAGAGTTACTCCCTGTGAAGAAATTTGAAAGTGAGATTCTGGAAGCAATCAGTCAAAATTC
AGTTGTCATTATTAGAGGGGCTGCTGGATGTGGTAAAACCACACAGGGTCCCCAGTTCATTCTAGATGACTTTATCCAGA
ATGACTGACAGCAGAGTGTAACATTGTAGTAACTCAGCCCAGAAGAATCAGTGTAGTTTCCGTGGCAGAGCGAGTTGCAT
TTGAGAGAGGAGAAGAGCCTGTAAACAGCTGTGGTTACAGTGTTCAATTTGAGTCTGTACTTCCTTGTCCTCATGCCAGT
ATAATGTTTTGTACTGTAGGTGTGCTCCTAAGAAAATTAGAAGCAGGCATTTGAGGAATCAGTCATGTAATTGTAGATGA
AATACATGGAAGAGACATTAATACTGACTTCCTTTTGGTAGTACTGCGTGAGGTTGTTTGAGCTTACCCTGAAGTTCTCA
TTGTTCTTATGTCCACTTCTATTGATACCAGCATGTTGTGTGAATATTTCTTCAATTGCCCCATCATTTAAGTGTATGGG
AGGACTTACCCAGTTCAAGAATATTTTCTGGAAGACTGCATTCAGATGACCCACTTTGTTCCTTCACCGAAAAACAACAA
GAAGGACAAGGATGATGATGGTGGTGAGGATGATGATGCAAATTGCAACTTGATCCGTGGTGATGAATATGGTCCAGAAA
CAAGGATGAGCATGTCTCAATTGAATGAAAAAGAAACTCCTTTTGAACTCGTCGAAGCTCTCTTTAAGTACATTGAAACC
CTTAATATTCCCAGAGCTGTGTTGGTATTTTTGCCTGGCTGGAATTTGATTTATACTATGCAGAAGCATTTGGAAATGAA
TCCACATTTTGGAAGCCATCAGTATCAGATTCTACCTCTGCATTCTCAGATTCCTCGACAGGAACAGCGCAAAGTGTTTG
ATCCAGTACCAGTTGGAGTAACCGAGGTTATTTTGTCCACAAATATTGCTGAAACAAGCATTATCATAAATGATGTTGTT
TATGTCATTGACTCCTGCAAGCAGAAAGTGAAACTCTTCGCTACTCACAACAATATGACCAACTATGCTACAGTATGGGG
ATCAAAAACAAACCCTGAACAGCGGAAAGGGCGAGCTGGCCGAATACGGCCTGGATTCTGCTTTCACCTCTGCAGCCGAG
CTCGTTTTGAGAGACTTGAAACCCACATGACACCAGAGATGTTCCAAACACCATTGCATGAAGTTGCTCTTAGCATAAAA
CTTCTGTGTCTAGTTGGAATTGGCCAGTTTCTGGTCAAAGCAATTGAAACTCTCCCTTTGGATGCTGTGATTGAAGCAGA
ACACACTCTTAGAGAGCTTGATGCATTAGATGCCAATGATGATTTGACTCCATTGGGACGAATCCTGGCTAACCTCCCCA
TTGAGCCTCGTTTTGGCAAAATGATGATAATGGTGTGTATTTTCTATGTGGGAGATGCTATCTGTACCATTCCTGCTGCT
ACCTGCTTTCCAGAGCATTTTATCAATGAAGGAAAGCGGCTGGGCTACAACCATCAAAATTTTGCTGGAAACAGATTTTC
TCATCATGTAGCCCTTTTATCAGTATTCCAAGCCAGAGATGATACTAGAATGGGTGGAGAAGAAGCAGAGATACGTTTTT
GTGCGCACAAAAGACTTAATATGGCTACACTAAGAATGACTTGGGAAGTCAAAGTTCAGCTCAAAGAGATTCTGATTAAT
TCTGGGTTTCCAGAAGATTGTTTGGTGACACAAGTGTTTACTAGCACTGGACCAGATAATAATTTAGATGTTGTTATCTC
CCTTCCTGGCCTTTGGTGTGTACCCCAATGTATGCTATCATAAGGAAAAGACAAAGATTCTCACCACTGAAGGGTGTAAT
GCACTTATCCACAAATCATCTGTTAATTGTCCTTTTAGTAGCCAAGACATGAAGTACCCATCTCCCTTCTTTGTATTTGG
TGAAAAGATTCGAACTCGAGCCATCTCCGCTAAAGGCATGACTTTAGTCACCCCACTGCAGTTGCTTCTCTTTGCCTCCA
AGAAAGTCCAATCTGATGGGCAGATTGTGCTTGCAGATGACTGGATTAAACTGCAAATATCTCATGAAGCTGCTGCCTGC
ATCACCGCTCTCCAGGCAGCCACGGAGGCTCTGGTTGTTGAAGTAACCAAACAACCTGCTATCATCAGCCAGTTGGACCC
CGTAAATGAAAGTATACTGAACATGATCCGTCAAATCTCTAGACCCTCAGCTGCTGATATCAACCTTATGATCGGCAGTA
CATGGTATGGAGATGGTCCAGGTCCTCCTAAGATGGCCCGATATGACAATGGAAGCGGATATAGAAGGGGAGGTTCTAGT
TATGGCAATGAAGGCTATGGCAGTGGCTATAGCAGTGGAGGCTATCGTAGCGGAGGCTATGGTGGCAGCTCCAGCTCTTG
TCAGGCAGGATATGGTGCAGGTGTTGGTGGAGGCTATAGAGAAGTTTCCCAAGGTGGCTATAGAGGCAACTCTGGAGGAG
ATTACAGAGGGCCTAGTAGAGGCTACAGATGATCTGGGGGATTCCAGCGAGGAGGTGGTAGGGGGGCCTATGGAACTGGC
TACTTTGGACAAGGAAGAGAAGGTGGCATCTAT

Alignment

ORF - retro_ggor_947 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.11 %
• Parental protein coverage: 89.21 %
• Number of stop codons detected: 6
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  TWDRGANLKDYYSRKEEQEVQATLESEEVDLNAGLHGNWTLENAKARLNQYFQKEKIQGEYKYTQVGPDH
          .WD.GANLKDYYSRKEEQEVQ..LESEEVDLNAGLHGNWT.ENAK..LNQYFQKEKIQGEY.YTQVGPDH
Retrocopy SWDQGANLKDYYSRKEEQEVQVNLESEEVDLNAGLHGNWTSENAKTHLNQYFQKEKIQGEYEYTQVGPDH

Parental  NRSFIAEMTIYIKQLGRRIFAREHGSNKKLAAQSCALSLVRQLYHLGVVEAYSGLTKKKEGETVEPYKVN
          NRSF.AE.T.YIKQLGRRIFA.EHGSNKKLAAQSCA.SLVRQLYHLGVVEAY.GLTKK.EGE.VEPYKVN
Retrocopy NRSFTAEITVYIKQLGRRIFAHEHGSNKKLAAQSCAMSLVRQLYHLGVVEAYFGLTKK-EGERVEPYKVN

Parental  LSQDLEHQLQNIIQELNLEILPPPEDPSVPVALNIGKLAQFEPSQRQNQVGVVPWSPPQSNWNPWTSSNI
          LS.DL.HQ.QNII.ELNLEI.PPPEDPS.PVALNIGKLA.FEPS..QNQVG.VP.SPPQS.WNPWT.SNI
Retrocopy LSRDLQHQPQNII*ELNLEIMPPPEDPSMPVALNIGKLAHFEPSR*QNQVGIVPRSPPQSRWNPWTTSNI

Parental  DEGPLAFATPEQISMDLKNELMYQLEQDHDLQGILQERELLPVKKFESEILEAISQNSVVIIRGATGCGK
          .EGPLAFA.PEQIS.DLKNEL.YQLEQDHDL..ILQE.ELLPVKKFESEILEAISQNSVVIIRGA.GCGK
Retrocopy AEGPLAFASPEQISLDLKNELVYQLEQDHDLPAILQEQELLPVKKFESEILEAISQNSVVIIRGAAGCGK

Parental  TTQVPQFILDDFIQND-RAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASI
          TTQ.PQFILDDFIQND...AECNIVVTQPRRIS.VSVAERVAFERGEEP..SCGYSV.FES.LP.PHASI
Retrocopy TTQGPQFILDDFIQND<LTAECNIVVTQPRRISVVSVAERVAFERGEEPVNSCGYSVQFESVLPCPHASI

Parental  MFCTVGVLLRKLEAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFF
          MFCTVGVLLRKLEAGI.GISHVIVDEIH.RDINTDFLLVVLR.VV.AYPEV.IVLMS..IDTSM.CEYFF
Retrocopy MFCTVGVLLRKLEAGI*GISHVIVDEIHGRDINTDFLLVVLREVV*AYPEVLIVLMSTSIDTSMLCEYFF

Parental  NCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANCNLICGDEYGPETRLSMSQ
          NCPII.VYGRTYPVQEYFLEDCIQMTHFVP.PK..KK.DKDDDGGEDDDANCNLI.GDEYGPETR.SMSQ
Retrocopy NCPII*VYGRTYPVQEYFLEDCIQMTHFVPSPKNNKK-DKDDDGGEDDDANCNLIRGDEYGPETRMSMSQ

Parental  LNEKETPFELIEALLKYIETLNVPGAVLVFLPGWNLIYTMQKHLEMNPHFGSHRYQILPLHSQIPREEQR
          LNEKETPFEL.EAL.KYIETLN.P.AVLVFLPGWNLIYTMQKHLEMNPHFGSH.YQILPLHSQIPR.EQR
Retrocopy LNEKETPFELVEALFKYIETLNIPRAVLVFLPGWNLIYTMQKHLEMNPHFGSHQYQILPLHSQIPRQEQR

Parental  KVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAG
          KVFDPVPVGVT.VILSTNIAETSI.INDVVYVIDSCKQKVKLF..HNNMTNYATVW.SKTN.EQRKGRAG
Retrocopy KVFDPVPVGVTEVILSTNIAETSIIINDVVYVIDSCKQKVKLFATHNNMTNYATVWGSKTNPEQRKGRAG

Parental  RVRPGFCFHLCSRARFERLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTL
          R.RPGFCFHLCSRARFERLETHMTPEMF.TPLHE.ALSIKLL.L.GIGQFL.KAIE..PLDAVIEAEHTL
Retrocopy RIRPGFCFHLCSRARFERLETHMTPEMFQTPLHEVALSIKLLCLVGIGQFLVKAIETLPLDAVIEAEHTL

Parental  RELDALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKRLGYIHRN
          RELDALDAND.LTPLGRILA.LPIEPRFGKMMIM.CIFYVGDAICTI.AATCFPE.FINEGKRLGY.H.N
Retrocopy RELDALDANDDLTPLGRILANLPIEPRFGKMMIMVCIFYVGDAICTIPAATCFPEHFINEGKRLGYNHQN

Parental  FAGNRFSDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFPEDCLLT
          FAGNRFS.HVALLSVFQA.DD.RMGGEEAEIRFC.HKRLNMATLRMTWE.KVQLKEILINSGFPEDCL.T
Retrocopy FAGNRFSHHVALLSVFQARDDTRMGGEEAEIRFCAHKRLNMATLRMTWEVKVQLKEILINSGFPEDCLVT

Parental  QVFTNTGPDNNLDVVISL-LAFGVYPNVCYHKEKRKILTTEGRNALIHKSSVNCPFSSQDMKYPSPFFVF
          QVFT.TGPDNNLDVVISL.LAFGVYPNVCYHKEK.KILTTEG.NALIHKSSVNCPFSSQDMKYPSPFFVF
Retrocopy QVFTSTGPDNNLDVVISL>LAFGVYPNVCYHKEKTKILTTEGCNALIHKSSVNCPFSSQDMKYPSPFFVF

Parental  GEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQIVLVDDWIKLQISHEAAACITGLRAAMEALVVEVT
          GEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQIVL.DDWIKLQISHEAAACIT.L.AA.EALVVEVT
Retrocopy GEKIRTRAISAKGMTLVTPLQLLLFASKKVQSDGQIVLADDWIKLQISHEAAACITALQAATEALVVEVT

Parental  KQPAIISQLDPVNERMLNMIRQISRPSAAGINLMIGSTRYGDGPRPPKMARYDNGSGYRRGGSSYSGGGY
          KQPAIISQLDPVNE..LNMIRQISRPSAA.INLMIGST.YGDGP.PPKMARYDNGSGYRRGGSSY...GY
Retrocopy KQPAIISQLDPVNESILNMIRQISRPSAADINLMIGSTWYGDGPGPPKMARYDNGSGYRRGGSSYGNEGY

Parental  GGGYSSGGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGA
          G.............GGS..S..AGYGAGVGGGYR.VS.GG.RGNSGGDYRGPS.GYR.SGGFQRGGGRGA
Retrocopy GSXXXXXXXXXXXXGGSSSSCQAGYGAGVGGGYREVSQGGYRGNSGGDYRGPSRGYR*SGGFQRGGGRGA

Parental  YGTGYFGQGRGGGGY
          YGTGYFGQGR.GG.Y
Retrocopy YGTGYFGQGREGGIY

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	114.85 RPM
SRP007412_cerebellum	0.00 RPM	112.84 RPM
SRP007412_heart	0.00 RPM	23.67 RPM
SRP007412_kidney	0.00 RPM	123.57 RPM
SRP007412_liver	0.00 RPM	56.90 RPM
SRP007412_testis	0.00 RPM	217.66 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_947 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_947 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1216
Pan troglodytes	retro_ptro_833

---

Parental genes homology:

Parental genes homology involve 3 parental genes, and 3 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000135829	1 retrocopy	retro_hsap_1216,
Gorilla gorilla	ENSGGOG00000013533	1 retrocopy	retro_ggor_947 ,
Pan troglodytes	ENSPTRG00000001759	1 retrocopy	retro_ptro_833,