RetrogeneDB ID:

retro_hsap_760

Retrocopy
location
Organism:Human (Homo sapiens)
Coordinates:11:23425189..23426645(+)
Located in intron of:None
Retrocopy
information
Ensembl ID:ENSG00000255293
Aliases:None
Status:KNOWN_PSEUDOGENE
Parental gene
information
Parental gene summary:
Parental gene symbol:WIZ
Ensembl ID:ENSG00000011451
Aliases:WIZ, ZNF803
Description:widely interspaced zinc finger motifs [Source:HGNC Symbol;Acc:30917]


Retrocopy-Parental alignment summary:






>retro_hsap_760
ATGGTGGCCATGGACCTGGGCTCTCTTCACTCCCTAAGAAAAGCCTGCCTGTCCCTGGGGCCCTGGAGCAGGTGGCCAGT
TGGCTGAGCAGCAAAGTGGCTCCAGAGGTTCCTCATGGCAGCAAACAGGAGCTGCAGGACCTCAGATCCCAGAGCCTGCC
ACCTGCAAGGTCTGTGGCGCCTGCTTTGGGACCGGAAAGGGCCTGTCCATCCACACACGCTCCCACCTGCGGCAGCTGGG
AGTGGCAGAGTCAGAGACGAGCGGCGTACCCATCAACCTCCTCTAGGAGCTTGTGAAGCAGAAGAGCATGCCCGACGCCC
ACCTTGGGCTGCCCCCGGGCCTGGCTAAGAAGTCCAGCTGGCTGAAGGAGGTGGTCGCCCGGGACCCCGGCCCGGCTTGC
TTACCCTGGCCAAATCCTTGGATGCCCCTGCTGTCAACAAAACCATCAAGTTGCCTCTCGGCTTCTCGACCAAGGGCCTG
GGCCAACTCCCAGCTCTCCGCTCCTTGAAAAGACACCACTGGCCCTGGAGGGCTCCCCTACTCCTAAGAATCCTGAGGAC
AAGAGCCCCGAGCTATCCCCGAGCCCATGGCCGGCCTCCCAAAAGGCACAGTGGCCTCAGTCAGGCCCTTGAACCTCACC
TCAGGCCTAGAGCCAGCACAAGAAATCTGTTGCTGTGAGTTCTCTGGTGAGTTCTTCTAGAACCGCAAGGGCCACTCGAG
CCACACGGGCTCCCACCTGCAGCAAATAGGCGTGACCGGGGGGTACGTCAATGGCTCGCCCATCGACAGACTGTGGGAGA
TCCTGAAGAGACGGACCCAGTTTCGCTCTGGCAGACCTCCCAACCCGCCAGGGCCAAGTCCAAAAGCCCTGGCCAAGATG
ATGGACGGCACAGGTCCTGGCAGCTCACTGGAAACCCGCAGCCCCTCTGACCTTCACATCTCACCCTTGGCCAAGAAGTT
GCCGCCGCCACCAGGCAGACCCCTGGGCCACTCACCAACTGCCTTTCCTCCTCCCGTGCCCGGAAGATGTTCCCAGGTCT
GGCTGCACACTCCCTGCCCAAGAAGCTGAAGCCTGAACAAATACGGGTGGAGATCAAGCGGGAGATGCTGCCGGGGGCCC
TTCGTGGGGAGCTGCACCCATCTGAGAGTCCCTGGGAGGCACCACGGGAAGACATGATACCCCTGAACCTGTCTTCCCGG
GCAGAGCCGGTGCGCAATATCCCCTGTGAGTTCTGCAGCGGGTTCTTTGAGAACCGCAAGGGCCTGTGTAGTCACGCACG
CTCCCACTTGCTGCAGATGGGTGTGACCGGGTGGTCCGTCCATGGTTCGCCCATTGACACTGCGAGAGATCCTCAAGAAG
TCCAAGCTGTGCCTCATCAAGGAGGAGCCACTGGCTGCAGACCTGGCCCCGGCCTTGGCTGAGGATGGGCCTCCCACTGT
GGTCCCTGGGCCCGTT

ORF - retro_hsap_760 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 80.56 %
Parental protein coverage: 58.8 %
Number of stop codons detected: 2
Number of frameshifts detected 7


Retrocopy - Parental Gene Alignment:

ParentalMVAMDLGS-PSLPKKSLPVPGALEQVASRLSSKVAAEVPHGSKQELQDLKAQSL-TTCEVCGACFETRKG
MVAMDLGS..SLPKKSLPVPGALEQVAS.LSSKVA.EVPHGSKQELQDL..QSL..TC.VCGACF.T.KG
RetrocopyMVAMDLGS<SSLPKKSLPVPGALEQVASWLSSKVAPEVPHGSKQELQDLRSQSL<ATCKVCGACFGTGKG
ParentalLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAHLGLPPGLAKKSSSLKEVVAG-APRPGLLSL
LS.H.RSHLRQLGVAESE.SG.PI.LL.ELVKQK..PDAHLGLPPGLAKKSS.LKEVVA...PRPGLL.L
RetrocopyLSIHTRSHLRQLGVAESETSGVPINLL*ELVKQKSMPDAHLGLPPGLAKKSSWLKEVVAR<GPRPGLLTL
ParentalAKPLDAPAVNKAIKSPPGFSAKGLGH-PPSSPLLKKTPLALAGSPTPKNPEDKSPQLSLSPRPASPKAQW
AK.LDAPAVNK.IK.P.GFS.KGLG...PSSPLL.KTPLAL.GSPTPKNPEDKSP.LS.SP....P..Q.
RetrocopyAKSLDAPAVNKTIKLPLGFSTKGLGQ<TPSSPLLEKTPLALEGSPTPKNPEDKSPELSPSPW---PASQK
ParentalPQSEDEGP-LNLTSGPEPARDIRC-EFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKR
.Q....GP.LNLTSG.EPA..I.C.EF.GEFF.NRKG.SSH..SHL.Q.GVT..YVNGSPID.L.EILKR
RetrocopyAQWPQSGP<LNLTSGLEPAQEICCCEFSGEFF*NRKGHSSHTGSHLQQIGVTGGYVNGSPIDRLWEILKR
ParentalRTQSRPGGPPNPPGPSPKALAKMMGGAGPGSSLEARSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPT-
RTQ.R.G.PPNPPGPSPKALAKMM.G.GPGSSLE.RSPSDLHISPLAKKLPPPPG.PLGHSPTA.PPP..
RetrocopyRTQFRSGRPPNPPGPSPKALAKMMDGTGPGSSLETRSPSDLHISPLAKKLPPPPGRPLGHSPTAFPPPV<
ParentalARKMFPGLAAPSLPKKLKPEQIRVEIKREMLPGALHGELHPSEGPWGAPREDMTPLNLSSRAEPVRDIRC
ARKMFPGLAA.SLPKKLKPEQIRVEIKREMLPGAL.GELHPSE.PW.APREDM.PLNLSSRAEPVR.I.C
RetrocopyARKMFPGLAAHSLPKKLKPEQIRVEIKREMLPGALRGELHPSESPWEAPREDMIPLNLSSRAEPVRNIPC
ParentalEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGS-PIDTLREILKKKSKPCLIKKEPPAGDLAPALAEDG
EFC..FFENRKGL.SHARSHL.QMGVT.WSV.GS.P..TLREILKK.SK.CLIK.EP.A.DLAPALAEDG
RetrocopyEFCSGFFENRKGLCSHARSHLLQMGVTGWSVHGS>PL-TLREILKK-SKLCLIKEEPLAADLAPALAEDG
ParentalPPTVAPGPV
PPTV.PGPV
RetrocopyPPTVVPGPV

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






RNA-Seq - click to see more details

(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
bodymap2_adipose 0 .00 RPM 42 .14 RPM
bodymap2_adrenal 0 .00 RPM 31 .22 RPM
bodymap2_brain 0 .00 RPM 11 .11 RPM
bodymap2_breast 0 .00 RPM 25 .58 RPM
bodymap2_colon 0 .00 RPM 26 .22 RPM
bodymap2_heart 0 .00 RPM 19 .48 RPM
bodymap2_kidney 0 .00 RPM 20 .37 RPM
bodymap2_liver 0 .00 RPM 11 .43 RPM
bodymap2_lung 0 .00 RPM 19 .94 RPM
bodymap2_lymph_node 0 .00 RPM 27 .63 RPM
bodymap2_ovary 0 .00 RPM 35 .47 RPM
bodymap2_prostate 0 .00 RPM 31 .44 RPM
bodymap2_skeletal_muscle 0 .00 RPM 30 .14 RPM
bodymap2_testis 0 .02 RPM 54 .26 RPM
bodymap2_thyroid 0 .00 RPM 23 .05 RPM
bodymap2_white_blood_cells 0 .00 RPM 14 .41 RPM

ChIP-Seq - click to see more details

RNA Polymerase II actvity near the 5' end of retro_hsap_760 was not detected

EST - click to see more details

No EST(s) were mapped for retro_hsap_760 retrocopy.

TSS - click to see more details



TSS No. TSS Name TSS expression level (Expr) in TPM range:
no expression 0 < Expr ≤ 1 1 < Expr ≤ 5 5 < Expr ≤ 10 Expr > 10
TSS #1 TSS_131101163 libraries439 libraries221 libraries5 libraries1 library

The graphical summary, for retro_hsap_760 TSS expression levels > 0 TPM .
TSS expression levels were studied across 1829 TSS-CAGE libraries, based on FANTOM5 data.
The expression values were visualized using beanplot. If you have any doubts, how to read it, read more in Kampstra P (2008)

Display detail expression values in each library
... or ...
Directly download all expression values

Lab - click to see more details

retro_hsap_760 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_hsap_760 has 0 orthologous retrocopies within eutheria group .

Parental genes homology:
Parental genes homology involve 2 parental genes, and 2 retrocopies.

Species Parental gene accession Retrocopies number
Homo sapiens ENSG00000011451 1 retrocopy
retro_hsap_760 ,
Macaca mulatta ENSMMUG000000288631 retrocopy
retro_mmul_1099,

Expression level across human populations :
image/svg+xml GBR_HG00142 GBR_HG00099 GBR_HG00114 GBR_HG00143 GBR_HG00131 GBR_HG00137 GBR_HG00133 GBR_HG00119 GBR_HG00111 GBR_HG00134 FIN_HG00378 FIN_HG00338 FIN_HG00349 FIN_HG00375 FIN_HG00315 FIN_HG00277 FIN_HG00328 FIN_HG00321 FIN_HG00377 FIN_HG00183 TSI_NA20756 TSI_NA20538 TSI_NA20798 TSI_NA20532 TSI_NA20765 TSI_NA20518 TSI_NA20513 TSI_NA20512 TSI_NA20771 TSI_NA20786 YRI_NA19114 YRI_NA19099 YRI_NA18870 YRI_NA18907 YRI_NA19223 YRI_NA19214 YRI_NA18916 YRI_NA19093 YRI_NA19118 YRI_NA19213 Toscaniin Italia: Finnish inFinland: British in England and Scotland: Utah Residents (CEPH) with Northernand Western European Ancestry: Yoruba in Ibadan, Nigeria: CEU_NA12760 CEU_NA12827 CEU_NA12872 CEU_NA12751 CEU_NA12873 CEU_NA12400 CEU_NA11930 CEU_NA12004 CEU_NA11831 CEU_NA11843 No expression ( = 0 RPM ) Legend:


Library Retrogene expression
CEU_NA11831 0 .00 RPM
CEU_NA11843 0 .00 RPM
CEU_NA11930 0 .00 RPM
CEU_NA12004 0 .00 RPM
CEU_NA12400 0 .00 RPM
CEU_NA12751 0 .00 RPM
CEU_NA12760 0 .00 RPM
CEU_NA12827 0 .00 RPM
CEU_NA12872 0 .00 RPM
CEU_NA12873 0 .00 RPM
FIN_HG00183 0 .00 RPM
FIN_HG00277 0 .00 RPM
FIN_HG00315 0 .00 RPM
FIN_HG00321 0 .00 RPM
FIN_HG00328 0 .00 RPM
FIN_HG00338 0 .00 RPM
FIN_HG00349 0 .00 RPM
FIN_HG00375 0 .00 RPM
FIN_HG00377 0 .00 RPM
FIN_HG00378 0 .00 RPM
GBR_HG00099 0 .00 RPM
GBR_HG00111 0 .00 RPM
GBR_HG00114 0 .00 RPM
GBR_HG00119 0 .00 RPM
GBR_HG00131 0 .00 RPM
GBR_HG00133 0 .00 RPM
GBR_HG00134 0 .00 RPM
GBR_HG00137 0 .00 RPM
GBR_HG00142 0 .00 RPM
GBR_HG00143 0 .00 RPM
TSI_NA20512 0 .00 RPM
TSI_NA20513 0 .00 RPM
TSI_NA20518 0 .00 RPM
TSI_NA20532 0 .00 RPM
TSI_NA20538 0 .00 RPM
TSI_NA20756 0 .00 RPM
TSI_NA20765 0 .00 RPM
TSI_NA20771 0 .00 RPM
TSI_NA20786 0 .00 RPM
TSI_NA20798 0 .00 RPM
YRI_NA18870 0 .00 RPM
YRI_NA18907 0 .00 RPM
YRI_NA18916 0 .00 RPM
YRI_NA19093 0 .00 RPM
YRI_NA19099 0 .00 RPM
YRI_NA19114 0 .00 RPM
YRI_NA19118 0 .00 RPM
YRI_NA19213 0 .00 RPM
YRI_NA19214 0 .00 RPM
YRI_NA19223 0 .00 RPM

Indel association:

No indels were associated with its genomic coordinates. Based on Kabza et al. 2015 (PubMed).



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