RetrogeneDB ID: retro_mluc_1435

Retrocopy location

• Organism: Microbat (Myotis lucifugus)
• Coordinates: GL429838:2542393..2543759(+)
• Located in intron of: ENSMLUG00000001452

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ADSS
• Ensembl ID: ENSMLUG00000017320
• Aliases: None
• Description: Adenylosuccinate synthetase [Source:UniProtKB/TrEMBL;Acc:G1PWK8]

Sequence

>retro_mluc_1435
ATGGCGTTGGCTGAGACCCACCCGGCAGCATCCTCCCTGCCCAATGGCGACTGCGGCCGCCCCCGGGTGCGGCCCGGAGG
GAACCGGTTGACAGTGGTGCTCGGCGCACAGTGGGGCGACGAAGGCAAAGGGAAGGTGGTGGATCTGCTGGCACAGGACG
CGGACATCGTGTGCCGCTGCCAGGGAGGAAATAATGCCAGCCACACAGTTGTTATAGATTCCGGGAGTATGATTTTCATC
TTTTACCCAGTGGAATAATTAATCTAAATGTTACTGCATTCATTGGAAATGGTGTGGTACTTCATCTACCGGGATTATTT
GAGGAAGCAGAAAAAAATGTTAAAAAAGGAAAAGGTCTGGAAGGCTGGGAAAAAAGGCTTATCATATCTGACAGAGCTCA
TAATGTGTTTGATTTTCATCAAGCAGCTGATGGCATCCAGGAACAGCAGAGACAAGAACAAGCAGGAAGGAATTTGGGTA
CCACAAAAAAGGGCATCGGCCCAGTTTATTCTTCCAAAGCTGCTCGGAGTGGACTCAGGATGTGCGATCTGGTTTCTGAT
TTCAATGGCTTCTCTGAGAGGTTCAAAGTTCTGGCAAACGAGTACAAATCTATATACCCCACTTGGGAAATAGACATCGA
AGGTGAATTACAAAACTCAAGGGTTATATGGAAAGAATTTAACCAATGGTGAGAGACGGAGTGTATTTTCTATATGAGGC
CCTACATGGACCACCAAAGAAAATCTTGGTAGAAGGTGCAAATGCAGCACTTCTAGATATTGATTTTGGAACTTACCCTT
TTGTAACTTCCTCGAACTGTACAGTTGGAGGTGTTTGTACTGGATTGGGTATGACCCCTCAGAATATTGGGGAAGTGTGT
GGGGTTGTGAAAGCTTACACAACTAGAGTTGGTATCGGTGCCTTTCCTACAGAGCAAGACAACGAAATTGGAGAATTATT
ACAGACAAGGGGTGGAGAGTTTGGTGTGACTACTGGAAGGAAAAGAAGATGTGGCTGGTTGGATCTCGTTTTGCTTAAAT
ATGCTCATATGATTAATGGATTTACTGAGTTGGCACTTACCAAATTGGATATTTTGGACACGTTTACAGAAATTAAAGTT
GGAGTTGCTTACAAGTTAGATGGTGAAATTATACCTCATTTCCCAGCAAACCAAGAGATCTTAAATAAAGTTTAAGTTCA
ATATAAGACTCTTCCAGGATGGAACACAGACATATCAAATGCAAGAATGTTTAAAGAACTGCCAGTTAACGCACAAAATT
ACGTTTGATTTGTTGAAGATGAGCTTCAGATTCCAGTTAAATGGATTGGTGTAGGGAAGACCAGAGAGTCTATGATTCAA
CTTTTC

Alignment

ORF - retro_mluc_1435 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 92.17 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MALAETHPAASS-PNGDCGRPRARPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTV
          MALAETHPAASS.PNGDCGRPR.RPGGNR.TVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNA.HTV
Retrocopy MALAETHPAASSLPNGDCGRPRVRPGGNRLTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNASHTV

Parental  VVDSV-EYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVKKGKGLEGWEKRLIISDRAHIVFDF
          V.DS..EYDFHLLPSGIIN.NVTAFIGNGVV.HLPGLFEEA........GLEGWEKRLIISDRAH.VFDF
Retrocopy VIDSG<EYDFHLLPSGIINLNVTAFIGNGVVLHLPGLFEEAXXXXXXXXGLEGWEKRLIISDRAHNVFDF

Parental  HQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFDGFSERFKVLANQYKSIYPTL
          HQAADGIQEQQRQEQAG.NLGTTKKGIGPVYSSKAARSGLRMCDLVSDF.GFSERFKVLAN.YKSIYPT.
Retrocopy HQAADGIQEQQRQEQAGRNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFNGFSERFKVLANEYKSIYPTW

Parental  EIDIEGELQ-KLKGYMERIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGG
          EIDIEGELQ.KLKGYMERI.PMVRDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGG
Retrocopy EIDIEGELQ<KLKGYMERI*PMVRDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGG

Parental  VCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEVGELLQTRGGEFGVTTGRKRRCGWLDLVLLKY
          VCTGLGM.PQN.GEV.GVVKAYTTRVGIGAFPTEQDNE.GELLQTRGGEFGVTTGRKRRCGWLDLVLLKY
Retrocopy VCTGLGMTPQNIGEVCGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGGEFGVTTGRKRRCGWLDLVLLKY

Parental  AHMINGFTAIRLALTKLDILDTFTEIKVGVAYKLDGEIIPHFPANQEILNKVEVQYKTLPGWNTDISNAR
          AHMINGFT...LALTKLDILDTFTEIKVGVAYKLDGEIIPHFPANQEILNKV.VQYKTLPGWNTDISNAR
Retrocopy AHMINGFT--ELALTKLDILDTFTEIKVGVAYKLDGEIIPHFPANQEILNKV*VQYKTLPGWNTDISNAR

Parental  TFKELPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF
          .FKELPVNAQNYV.F.EDELQIPVKWIGVGK.RESMIQLF
Retrocopy MFKELPVNAQNYV*FVEDELQIPVKWIGVGKTRESMIQLF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Myotis lucifugus was not studied using RNA-Seq expression data.

ChIP-Seq

Myotis lucifugus was not studied using ChIP-Seq data.

EST

Myotis lucifugus was not studied using EST data.

TSS

Myotis lucifugus was not studied using FANTOM5 data.

Lab

retro_mluc_1435 was not experimentally validated.

Homology

Retrocopy orthology:

Myotis lucifugus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 4 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000015815	1 retrocopy	retro_cfam_322,
Myotis lucifugus	ENSMLUG00000017320	1 retrocopy	retro_mluc_1435 ,
Monodelphis domestica	ENSMODG00000006559	1 retrocopy	retro_mdom_1431,
Mustela putorius furo	ENSMPUG00000015741	1 retrocopy	retro_mputfur_1286,