RetrogeneDB ID: retro_mmul_142

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: X:77977453..77978179(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMMUG00000032415
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: GSTO1
• Ensembl ID: ENSMMUG00000015334
• Aliases: None
• Description: glutathione S-transferase omega-1 [Source:RefSeq peptide;Acc:NP_001247484]

Sequence

>retro_mmul_142
ATGTCCGGGGAGTCAGCCAGGAGCCTGGGGAAGGGAAGCGCGCCCCCGGGGCCGGTCCCGGAGGGCTCCATCCGCGTCTA
CAGCATGAGGTTCTGCCTGTTTGCTGAGAGGACGCGTCTGGTCCTGAAGGCCAAAGGAATCAGGCATGAACTCATCAGTA
TCAACCTGAAAAATAAGCCTGAGTGGTTCTTTAAGAAAAATCCCTTTGGTCTGGTGCCAGTTCTGGAAAACAGTCAGGAT
CAGCTGATCTGTGAGTCTCCCATCACCTGTGAGTACCTGGATGAGGCATACCCAGGGAAGAAGCTGTTGCCGGATGACTC
CTATGAGAAAGCTTGCCAGAAGATGATCTTAGAGCTGTTTTCTAAGTTGTCATCCTTAGTAAGAAGCTTTATTAGAAGCC
AAAATAAAGAAGACTATGCTGGCCTAAAAGAAGAATTTCGTAAAGAATTTACCGAGCTAGAGGAGGTTCTGAGTAATAAG
AAGACGATGTTCTTTGGTGACAATTCTCTCTCTATGATTGATTACCTCATCTGGCCCTGGTTTGAACGGCTGGAAGCAAT
GAGGTTATATGAGTGTGTAGACCACACTCCAAAACTTAAACTGTGGATGGCAGCCATGAAGGAAGATCCCACAGTCTCAG
CCCTGCTCACTAGTGAGAAGGACTGGCAAGGTTTCCTAGAGCTTTACTTACAGAACTGTCCTGAGGCCTGTGACTATGGG
CTCTGA

Alignment

ORF - retro_mmul_142 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 91.7 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MSRESARSLGKGSAPPGPVPEGSIRVYSMRFCPFAERTLLVLKAKGIRHEVININLKNKPEWFFKKNPFG
          MS.ESARSLGKGSAPPGPVPEGSIRVYSMRFC.FAERT.LVLKAKGIRHE.I.INLKNKPEWFFKKNPFG
Retrocopy MSGESARSLGKGSAPPGPVPEGSIRVYSMRFCLFAERTRLVLKAKGIRHELISINLKNKPEWFFKKNPFG

Parental  LVPVLENSQGQLIYESPITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYA
          LVPVLENSQ.QLI.ESPITCEYLDEAYPGKKLLPDD.YEKACQKMILELFSK..SLV.SFIRSQNKEDYA
Retrocopy LVPVLENSQDQLICESPITCEYLDEAYPGKKLLPDDSYEKACQKMILELFSKLSSLVRSFIRSQNKEDYA

Parental  GLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLYECVDHTPKLKLWMAAMKEDP
          GLKEEFRKEFT.LEEVL.NKKT.FFG.NS.SMIDYLIWPWFERLEAM.LYECVDHTPKLKLWMAAMKEDP
Retrocopy GLKEEFRKEFTELEEVLSNKKTMFFGDNSLSMIDYLIWPWFERLEAMRLYECVDHTPKLKLWMAAMKEDP

Parental  TVSALLISGKDWQGFLELYLQNSPEACDYGL
          TVSALL.S.KDWQGFLELYLQN.PEACDYGL
Retrocopy TVSALLTSEKDWQGFLELYLQNCPEACDYGL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	19.61 RPM
SRP007412_brain_prefrontal_cortex	0.08 RPM	33.87 RPM
SRP007412_cerebellum	0.00 RPM	17.89 RPM
SRP007412_heart	0.00 RPM	17.72 RPM
SRP007412_kidney	0.00 RPM	14.08 RPM
SRP007412_liver	0.12 RPM	203.07 RPM
SRP007412_testis	0.00 RPM	1.13 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_142 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_142 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_142 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 8 parental genes, and 8 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000018474	1 retrocopy	retro_cjac_295,
Echinops telfairi	ENSETEG00000017967	1 retrocopy	retro_etel_1413,
Homo sapiens	ENSG00000148834	1 retrocopy	retro_hsap_2704,
Gorilla gorilla	ENSGGOG00000005064	1 retrocopy	retro_ggor_24,
Macaca mulatta	ENSMMUG00000015334	1 retrocopy	retro_mmul_142 ,
Nomascus leucogenys	ENSNLEG00000015358	1 retrocopy	retro_nleu_1577,
Pongo abelii	ENSPPYG00000002633	1 retrocopy	retro_pabe_2256,
Pan troglodytes	ENSPTRG00000002925	1 retrocopy	retro_ptro_1825,