RetrogeneDB ID:

retro_ocun_966

Retrocopy
location
Organism:Rabbit (Oryctolagus cuniculus)
Coordinates:18:7628474..7630838(+)
Located in intron of:ENSOCUG00000012865
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:HK1
Ensembl ID:ENSOCUG00000006697
Aliases:None
Description:hexokinase 1 [Source:HGNC Symbol;Acc:4922]


Retrocopy-Parental alignment summary:






>retro_ocun_966
AAGAAGATTGACAAGTATCTCTACGCCATGCAGCTCTCTGATGAAACTCTGGTAGATATCATGACTCGCTTCAAGAAGGA
GATGAAGAATGGCCTCTCCCAGGATTTTAACCCAACAGCCACAGTCAAGATGTTGCCAACGTTTGTAAGGTCCATTCCTG
ATGGTTCCGAAAAGGGAGATTTCATCGCCCTGGATCTCGGGGGGTCTTCCTTTCGGATTCTGTGGGTGCAAGTGAATCAC
GAGAAGAAGCAGAATGTCCACATGGAGTCCGAGGCCTACGAAACCCCCGAGAACATCGTGCATGGCAGCGGGAGCCAGCT
TTTCGATCATGTTGCTGAATGCCTGGGAGACTTCATGGAGAAAAGGAACATCAAGGACAACAAACTGCCCGTGGGATTCA
CCTTCTCGTTCCCTTGCCGACAATCAAAAATAGACGAGGCTGTCCTGATCACCTGGACAAAGCGATTCAAGGCGAGCGGC
GTGGAAGGGGCAGATGTGGTCAAGCTGCTGAACAAAGCCATCAAAAAGCGAGGGGACTATGACGCCAACATCGTGGCTGT
GGTGAACGACACGGTGGGGACCATGATGACATGTGGCTACGACGACCAGCAGTGTGAAGTCGGCCTGATTATTGGCACCG
GCACCAACGCGTGCTACATGGAGGAGCTGAGGCACATCGACCTGGTGGAGGGTGACGAGGGCAGGATGTGCATCAACACG
GAGTGGGGGGCCTTCGGCGACGACGGCGCCCTGGAAGACATCCGCACTGAGTTTGACAGGGAGATCGACCGGGGCTTGCT
CAACCCGGGGAAGCAGCTGTTCGAGAAGATGGTCAGTGGCATGTACATGGGGGAGCTGGTCCGGCTGATCCTGGTCAAGA
TGGCCAAAGAGGGCCTCTTGTTCGAAGGGTGAATCACCCCAGAGCTGCTCACCCGAGGGAAGTCCAACACCAGCGACGTG
TCAGCCATCAAAAAGAATAAGGAAGGCCTCCACAACGCCAAAGAGATCCTGACCCGCCTGGGAGTGGAGCCGTCCGACGA
TGACTGTATTTCCGTTCAGCATGTGTGCACCATTGTCTCGTTCCGCTCGGCCAACCTGGCGGCTGCCACGCTGGGCGCCA
TCTTGAACCGCCTGCGGGACAACAAGGGCACGCCCCGGCTACGCACCACCGTTGGTGTCGACGGCTCTCTGTACAAGACA
CACCCACAGTATTCCCGGCGTTTCCACAAGACCCTGAGGCGCCTGGTGCCTGACTCCGATGTGCGCTTCCTGCTGTCGGA
GAGTGGCAGCAGCAAGGGGGCTGCCATGGTGATGGCGGTGGCCTACCGCCTGGCTGAGCAGCACCGGCAGATAGAGGAGA
CCCTGGCCCACTTCCGCCTCACCAAGGAGATGCTGCTGGAGGTGAAGAAGAGGATGCGGACCGAGATGGAGGCGGGGCTG
AGGAGGCAGACGCACGACAAGGCCGTGGTCAAGATGCTGCCCTCCTTCGTCCGCAGCACCCCCGACGGCACCGAGAACGG
TGACTTCTTGGCCCTGGATCTCGGAGGAACGAACTTCCGCGTCCTGTTGGTGAAAATCCATAGCAGGAAGAAGCACACAG
TGGAGATGCAAAACAAGATCTATGCCATCCCTCTGGAGATCATGCAGGGCACCGGGGAAGAGCTGTTCGACCACATCATC
TCCTGCATCTCCAACTTCCTGGACTACATGGGAATCAAGGGCCCGCGGATGCCACTGGGCTTCACATTCTCGTTCCCCTG
CAAGCAGACGAGTCTCGACGCGGGAATCTTGGTCACCTGGACCAAAGGCTTCAAGGCAACTGACTGCGTGTGCCATGACG
TAGCCACTTTACTGAGGGACGCCATCAAAAGGAGAGAGGAATTTGACCTGGATGTGGTGGCCATGGTCAATGACACGGTG
GGCACCATGATGACCTGTGCATACGAGGAGCCCACCTGCGAGGTTGGACTTATTGTAGGGACGGGCTGCAATGCCTGCTA
CATGGAGGAGATGAGGAACGTGGAGATGCTGGAGGGGAACGAGGGGCAGATGTGCATCAACATGGAGTGGGGCGCCTTTG
GTGACAACGGTTGTCTGGATGACATCAGAACCATCTATGACCGACTGGTGGACGAATATTCTCTAAACGCTGGGAAGCAG
AGGTACGAGAAGATGATCAGCGGCATGTACCTGGGGGAGATCGTCTGCAACATCCTCATAGACTTCAAGAAGGGCTTCCT
CTTCTGCGGGCAGGTCTCCGAGCCGCTCAAGACGAGGGGCATCTTTGAGACCAAGTTCCTCTCTCAGATCGAGAGCGACC
GGCTGGCGCTGCTCCAGGTGCGGGCCATCCTCCAGCAGCTGGGT

ORF - retro_ocun_966 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 97.34 %
Parental protein coverage: 85.67 %
Number of stop codons detected: 1
Number of frameshifts detected 0


Retrocopy - Parental Gene Alignment:

ParentalKKIDKYLYAMRLSDETLVDIMTRFKKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSS
KKIDKYLYAM.LSDETLVDIMTRFKKEMKNGLS.DFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSS
RetrocopyKKIDKYLYAMQLSDETLVDIMTRFKKEMKNGLSQDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSS
ParentalFRILRVQVNHEKKQNVHMESEAYETPENIVHGSGSQLFDHVAECLGDFMEKRNIKDKKLPVGFTFSFPCR
FRIL.VQVNHEKKQNVHMESEAYETPENIVHGSGSQLFDHVAECLGDFMEKRNIKD.KLPVGFTFSFPCR
RetrocopyFRILWVQVNHEKKQNVHMESEAYETPENIVHGSGSQLFDHVAECLGDFMEKRNIKDNKLPVGFTFSFPCR
ParentalQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLI
QSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLI
RetrocopyQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLI
ParentalIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDREIDRGSLNPGKQLFEKMVSG
IGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDREIDRG.LNPGKQLFEKMVSG
RetrocopyIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDREIDRGLLNPGKQLFEKMVSG
ParentalMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCI
MYMGELVRLILVKMAKEGLLFEG.ITPELLTRGK.NTSDVSAI.KNKEGLHNAKEILTRLGVEPSDDDCI
RetrocopyMYMGELVRLILVKMAKEGLLFEG*ITPELLTRGKSNTSDVSAIKKNKEGLHNAKEILTRLGVEPSDDDCI
ParentalSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD
SVQHVCTIVSFRSANL.AATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD
RetrocopySVQHVCTIVSFRSANLAAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSD
ParentalVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFRLTKEMLLEVKKRMRTEMEAGLRRQTHDKAVV
VRFLLSESGS.KGAAMV.AVAYRLAEQHRQIEETLAHFRLTKEMLLEVKKRMRTEMEAGLRRQTHDKAVV
RetrocopyVRFLLSESGSSKGAAMVMAVAYRLAEQHRQIEETLAHFRLTKEMLLEVKKRMRTEMEAGLRRQTHDKAVV
ParentalKMLPSFVRSTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPLEIMQGTGEELFDHIV
KMLPSFVRSTPDGTENGDFLALDLGGTNFRVLLVKI.S.KK.TVEM.NKIYAIPLEIMQGTGEELFDHI.
RetrocopyKMLPSFVRSTPDGTENGDFLALDLGGTNFRVLLVKIHSRKKHTVEMQNKIYAIPLEIMQGTGEELFDHII
ParentalSCISDFLDYMGIKGPRMPLGFTFSFPCKQTSLDAGILVTWTKGFKATDCVGHDVATLLRDAIKRREEFDL
SCIS.FLDYMGIKGPRMPLGFTFSFPCKQTSLDAGILVTWTKGFKATDCV.HDVATLLRDAIKRREEFDL
RetrocopySCISNFLDYMGIKGPRMPLGFTFSFPCKQTSLDAGILVTWTKGFKATDCVCHDVATLLRDAIKRREEFDL
ParentalDVVAMVNDTVGTMMTCAYEEPTCEVGLIVGTGCNACYMEEMRNVEMLEGNEGQMCINMEWGAFGDNGCLD
DVVAMVNDTVGTMMTCAYEEPTCEVGLIVGTGCNACYMEEMRNVEMLEGNEGQMCINMEWGAFGDNGCLD
RetrocopyDVVAMVNDTVGTMMTCAYEEPTCEVGLIVGTGCNACYMEEMRNVEMLEGNEGQMCINMEWGAFGDNGCLD
ParentalDIRTIYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQVSEPLKTRGIFETKFLSQ
DIRTIYDRLVDEYSLNAGKQRYEKMISGMYLGEIV.NILIDF.KKGFLF.GQVSEPLKTRGIFETKFLSQ
RetrocopyDIRTIYDRLVDEYSLNAGKQRYEKMISGMYLGEIVCNILIDF-KKGFLFCGQVSEPLKTRGIFETKFLSQ
ParentalIESDRLALLQVRAILQQLG
IESDRLALLQVRAILQQLG
RetrocopyIESDRLALLQVRAILQQLG

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP017611_brain 23 .68 RPM 310 .66 RPM
SRP017611_kidney 12 .06 RPM 97 .00 RPM
SRP017611_liver 0 .46 RPM 7 .78 RPM
Oryctolagus cuniculus was not studied using ChIP-Seq data.
No EST(s) were mapped for retro_ocun_966 retrocopy.
Oryctolagus cuniculus was not studied using FANTOM5 data.
retro_ocun_966 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_ocun_966 has 0 orthologous retrocopies within eutheria group .


Parental genes homology:
Parental genes homology involve 2 parental genes, and 2 retrocopies.

Species Parental gene accession Retrocopies number
Oryctolagus cuniculus ENSOCUG00000006697 1 retrocopy
retro_ocun_966 ,
Tupaia belangeri ENSTBEG000000163591 retrocopy



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