RetrogeneDB ID: retro_chof_225

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: GeneScaffold_4977:59018..59427(+)
• Located in intron of: ENSCHOG00000005948

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PRDX6
• Ensembl ID: ENSCHOG00000011367
• Aliases: None
• Description: peroxiredoxin 6 [Source:HGNC Symbol;Acc:16753]

Sequence

>retro_chof_225
GACATCAGTGCATACAATGGTGATGCGCTCGCAGAAACATTACCTTTTCCCATCATTGATGATAGGGGTTGGGACCTTGC
CATCTTGTTCGGAATGCTGGGCCCAGTAGAGAAGGACAGACAGGGCATGCCTGTGACAGCTCATGTGGTGTTTATTTTTG
GTCCTGATAGGAAACTGAAGCTGTCTATCCTCTATCCAGCTGCCACTGGAAGGAACTTTGATGAGATTCTCAGAGTAGTT
TCTCTCTAGCTTATGGCAGAAAAGAAGGTTTCTACCCCTATTGGTTGGAAGGATGGAGACAGTGTGATGGTCCTTCCAAC
CATCCTGGAAGAGGAAGCCAGAAAACTTCCCTTAAGGGCTCTTCACCAAAGAGCTCCCACCTGGCAAGAAGTATCTGCTA
CACTCCCCA

Alignment

ORF - retro_chof_225 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 68.35 %
• Parental protein coverage: 61.61 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  DINAYNGDEPTEKLPFPIIDDKNRDLAILLGMLDPAEKDEKGMPVTARVVFIFGPDKKLKLSILYPATTG
          DI.AYNGD...E.LPFPIIDD...DLAIL.GML.P.EKD..GMPVTA.VVFIFGPD.KLKLSILYPA.TG
Retrocopy DISAYNGDALAETLPFPIIDDRGWDLAILFGMLGPVEKDRQGMPVTAHVVFIFGPDRKLKLSILYPAATG

Parental  RNFDEILRVVISLQLTAEKRVATPVDWQAGGSVMVLPTIPEEEAKRIFPKGVFTKELPS-GKKYLRYTP
          RNFDEILRVV.SL.L.AEK.V.TP..W..G.SVMVLPTI.EEEA....P........P..GKKYL...P
Retrocopy RNFDEILRVV-SL*LMAEKKVSTPIGWKDGDSVMVLPTILEEEARKL-PLRALHQRAPT>GKKYLLHSP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_225 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 21 parental genes, and 40 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000015560	1 retrocopy	retro_amel_493,
Bos taurus	ENSBTAG00000004855	2 retrocopies	retro_btau_1325, retro_btau_1477,
Canis familiaris	ENSCAFG00000014579	1 retrocopy	retro_cfam_492,
Choloepus hoffmanni	ENSCHOG00000011367	6 retrocopies	retro_chof_1143, retro_chof_1361, retro_chof_1364, retro_chof_225 , retro_chof_2483, retro_chof_2598,
Callithrix jacchus	ENSCJAG00000009355	6 retrocopies	retro_cjac_1903, retro_cjac_2188, retro_cjac_3008, retro_cjac_3239, retro_cjac_3830, retro_cjac_4000,
Cavia porcellus	ENSCPOG00000011091	1 retrocopy	retro_cpor_623,
Equus caballus	ENSECAG00000022468	1 retrocopy	retro_ecab_215,
Erinaceus europaeus	ENSEEUG00000004040	1 retrocopy	retro_eeur_475,
Homo sapiens	ENSG00000117592	2 retrocopies	retro_hsap_1046, retro_hsap_3017,
Gorilla gorilla	ENSGGOG00000026357	1 retrocopy	retro_ggor_2086,
Macaca mulatta	ENSMMUG00000008776	1 retrocopy	retro_mmul_1928,
Monodelphis domestica	ENSMODG00000004032	2 retrocopies	retro_mdom_462, retro_mdom_661,
Mustela putorius furo	ENSMPUG00000004648	1 retrocopy	retro_mputfur_1328,
Mus musculus	ENSMUSG00000026701	2 retrocopies	retro_mmus_181, retro_mmus_2334,
Nomascus leucogenys	ENSNLEG00000015278	2 retrocopies	retro_nleu_2244, retro_nleu_917,
Pan troglodytes	ENSPTRG00000042455	1 retrocopy	retro_ptro_70,
Pteropus vampyrus	ENSPVAG00000002596	2 retrocopies	retro_pvam_1389, retro_pvam_805,
Rattus norvegicus	ENSRNOG00000002896	3 retrocopies	retro_rnor_2084, retro_rnor_754, retro_rnor_806,
Sarcophilus harrisii	ENSSHAG00000003248	1 retrocopy	retro_shar_478,
Tarsius syrichta	ENSTSYG00000010073	2 retrocopies	retro_tsyr_1395, retro_tsyr_193,
Tursiops truncatus	ENSTTRG00000008478	1 retrocopy	retro_ttru_1274,