RetrogeneDB ID: retro_cjac_3076

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 8:58387309..58388180(+)
• Located in intron of: ENSCJAG00000014282

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MKI67IP
• Ensembl ID: ENSCJAG00000013386
• Aliases: None
• Description: MKI67 (FHA domain) interacting nucleolar phosphoprotein [Source:HGNC Symbol;Acc:17838]

Sequence

>retro_cjac_3076
ATGGCGGCGTTATCTGGTCCGGCTGCGCCAGTCTTGTCGCTTAACCCGCAAGAAGATGTTGAGTTTCAAAAGGAGGTGGC
ACAGGTTCGCAAGCACATAACCCAGCAAAGCAAACAAGAACAACTTACCCCTGGAGTCGTCTATGTGCACCACCTGCCTA
ACCTACTTGACGAAACCCAGATCTTTTCCTGTTTCTCCCAGTTTGGCACTGTGACACGGTTCAGACTGCCCAGAAGTAAA
AGGACTGGAAACAGCAAAGGCTATGCATTTGTGGAGTTTGAGTGTAAGGATGTTGCCAAGATAGTTGCTGAAACAATGAA
CAGCTAAGTGTTTGGTGAAAGACTCTTGGAGTGTCGTCTTATGTCAACTAAAAAAGTACATAAAGAATTCTTTAAAGACT
GAAATGTTCCATTTAAGCAGCCATCACATCCGTCAGTGAAACAGTATAATCGGAATTGGACACTAACACAAAAGCTACGG
ATGGAGGAGAGATTTAAAAAGAAAGAAGGTTACTCAGGAAGAAATTAGCTAGGAAGGGAATCGATTATGATTTTCCTTCT
TTGATTTTACAGAAAACAGAAAGTATTTCAAAAACTAATCGTCAGAAGTCTACAAAAGGCCAGGTTTTACACAAGAAGAA
AAAGGTGGTCGGCACTCTTGACACTCCTGAGGAGTCAGTGCAGAGCCAGGGCCCCACACCAGTTTGTACACCAACATTTT
TGGAGAGACGAAAATCTGAAGTGACTGAAATGAAGATGATAAAGATAATGAAATAGTTTTCAAACAGCCTGTATTCTGTG
TAAAAGAAGAAATACAAAAGACTCGAACACCTGCACATTCACAGAAGAAAAGGCGAAGAAAAAGCAATCAG

Alignment

ORF - retro_cjac_3076 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.14 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MAVLSGPAAPVLSLNPQEDGEFQKEVAQVRKRITQRNKQEQLTPGVVYVRHLPNLLDETQIFSYFSQFGT
          MA.LSGPAAPVLSLNPQED.EFQKEVAQVRK.ITQ..KQEQLTPGVVYV.HLPNLLDETQIFS.FSQFGT
Retrocopy MAALSGPAAPVLSLNPQEDVEFQKEVAQVRKHITQQSKQEQLTPGVVYVHHLPNLLDETQIFSCFSQFGT

Parental  VTRFRLSRSKRTGNSKGYAFVEFECKDVAKIVAETMNNYLFGERLLECRLMPPKKVHKELFKDWNVPFKQ
          VTRFRL.RSKRTGNSKGYAFVEFECKDVAKIVAETMN...FGERLLECRLM..KKVHKE.FKD.NVPFKQ
Retrocopy VTRFRLPRSKRTGNSKGYAFVEFECKDVAKIVAETMNS*VFGERLLECRLMSTKKVHKEFFKD*NVPFKQ

Parental  PSHPSVKRYNRNRTLTQKLRMEERFKKKE-RLLRKKLARKGINYDFPSLILQKTESISKTNHQKSTKGQG
          PSHPSVK.YNRN.TLTQKLRMEERFKKKE.RLLRKKLARKGI.YDFPSLILQKTESISKTN.QKSTKGQ.
Retrocopy PSHPSVKQYNRNWTLTQKLRMEERFKKKE<RLLRKKLARKGIDYDFPSLILQKTESISKTNRQKSTKGQV

Parental  LHKKKKKVVGTLDTPEETVDSQGPTPVCTPAFLERRKSEVTGM-DEDDKDNEIVFKQPVSCVKEEVQKTQ
          LH.KKKKVVGTLDTPEE.V.SQGPTPVCTP.FLERRKSEVT.M...D.KDNEIVFKQPV.CVKEE.QKT.
Retrocopy LH-KKKKVVGTLDTPEESVQSQGPTPVCTPTFLERRKSEVTEM<EDD-KDNEIVFKQPVFCVKEEIQKTR

Parental  TPARSRKKRRRKSNQ
          TPA.S.KKRRRKSNQ
Retrocopy TPAHSQKKRRRKSNQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.00 RPM	13.07 RPM
SRP051959_heart	0.21 RPM	11.24 RPM
SRP051959_kidney	0.00 RPM	14.75 RPM
SRP051959_liver	0.02 RPM	14.62 RPM
SRP051959_lung	0.00 RPM	13.06 RPM
SRP051959_lymph_node	0.02 RPM	14.27 RPM
SRP051959_skeletal_muscle	0.00 RPM	10.18 RPM
SRP051959_spleen	0.00 RPM	15.63 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_3076 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_3076 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_3076 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 57 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000019387	1 retrocopy	retro_btau_1516,
Choloepus hoffmanni	ENSCHOG00000002227	5 retrocopies	retro_chof_1061, retro_chof_1449, retro_chof_1735, retro_chof_236, retro_chof_2480,
Callithrix jacchus	ENSCJAG00000013386	1 retrocopy	retro_cjac_3076 ,
Dasypus novemcinctus	ENSDNOG00000005017	2 retrocopies	retro_dnov_1869, retro_dnov_2487,
Erinaceus europaeus	ENSEEUG00000008535	3 retrocopies	retro_eeur_530, retro_eeur_550, retro_eeur_91,
Homo sapiens	ENSG00000155438	5 retrocopies	retro_hsap_1077, retro_hsap_1596, retro_hsap_1609, retro_hsap_1611, retro_hsap_553,
Gorilla gorilla	ENSGGOG00000023498	4 retrocopies	retro_ggor_1213, retro_ggor_1923, retro_ggor_2225, retro_ggor_850,
Loxodonta africana	ENSLAFG00000030731	1 retrocopy	retro_lafr_500,
Microcebus murinus	ENSMICG00000015787	1 retrocopy	retro_mmur_990,
Myotis lucifugus	ENSMLUG00000006481	2 retrocopies	retro_mluc_1217, retro_mluc_1369,
Macaca mulatta	ENSMMUG00000020928	11 retrocopies	retro_mmul_1444, retro_mmul_1544, retro_mmul_2149, retro_mmul_2151, retro_mmul_2225, retro_mmul_2226, retro_mmul_2389, retro_mmul_690, retro_mmul_696, retro_mmul_697, retro_mmul_752,
Monodelphis domestica	ENSMODG00000000152	2 retrocopies	retro_mdom_1271, retro_mdom_737,
Nomascus leucogenys	ENSNLEG00000001163	4 retrocopies	retro_nleu_1756, retro_nleu_1942, retro_nleu_2022, retro_nleu_669,
Pongo abelii	ENSPPYG00000025875	2 retrocopies	retro_pabe_2248, retro_pabe_510,
Pan troglodytes	ENSPTRG00000012419	5 retrocopies	retro_ptro_1072, retro_ptro_1077, retro_ptro_1080, retro_ptro_1378, retro_ptro_415,
Pteropus vampyrus	ENSPVAG00000016707	1 retrocopy	retro_pvam_134,
Sorex araneus	ENSSARG00000006252	1 retrocopy	retro_sara_362,
Tupaia belangeri	ENSTBEG00000001123	4 retrocopies	retro_tbel_1731, retro_tbel_3479, retro_tbel_4589, retro_tbel_926,
Vicugna pacos	ENSVPAG00000005847	2 retrocopies	retro_vpac_136, retro_vpac_265,