RetrogeneDB ID: retro_ggor_1950

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 3:79790463..79791198(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: GXYLT1
• Ensembl ID: ENSGGOG00000027928
• Aliases: None
• Description: None

Sequence

>retro_ggor_1950
AAACCACGTGCTTCGCAGAGATCATTCTTGCCTTTAATCCCGAAAGAAGTTGACTCCCTATTGTATGCCGACACTGATGG
CCTTTTTTATGACCCGTTGATGATATTTGGTCTTTATTAAAGAAATTTAACTCCACGCAAGTTGCTGCAATGGCACCAGA
ACATGGGGAACCTAGAATAGGATGGTATAGTCTCTTTGCTAGTCATCCATAATGTGGAAAAACTGGAGTAAACTCTGGAG
TTATGTTGACAAACATGACTCGAATGAGAATGAAGTGTTTCGAAAATGATATGACAACTGTGTGAATACAATGGGAAGAT
ATACTTATGACATGGCTTAAAAAATACAAGCTAGACATTACAGGGGCGATCAAAATCTGTTAAATATCATGTTTCTTCAT
AATCCAGAAAGCCTTTTTGTTTTTCCTCGTCAATGGAAGTGTCATCCAGATCATACTCTATATGGAAGCAGTTGCCAAGA
AGCAGAAGAAGGAATCTTTATTCTTCATGGGAACAGGGGTGTTTACCATGATGATAAGCAACCAGCATTTAGGGCTGTTT
ATGAGGCACTGAGAAATTGTTCTTTTAAGATGACAACGTTCATTCCCTAATAAAACCTTTAGAACTGGAACTACAAATAA
CAGTGCATACATACCGTGGAAAAATTTACAAAATATTTATCAAACAACTAGCAAAAAGCGTAAGAGATTGTTATGCTAGA
TCACCAAAGGAAAGG

Alignment

ORF - retro_ggor_1950 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.6 %
• Parental protein coverage: 56.14 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  KPCASQRLFLPLILKEIDSLLYVDTDILF-LRPVDDIWSLLKKFNSTQIAAMAPEHEEPRIGWYNRFARH
          KP.ASQR.FLPLI.KE.DSLLY.DTD.LF.L.PVDDIWSLLKKFNSTQ.AAMAPEH.EPRIGWY..FA.H
Retrocopy KPRASQRSFLPLIPKEVDSLLYADTDGLF<L*PVDDIWSLLKKFNSTQVAAMAPEHGEPRIGWYSLFASH

Parental  PYYGKTGVNSGVMLMNMTRMRRKYFKNDMTTVRLQWGDILMPLLKKYKLNITW-GDQDLLNIMFFHNPES
          P..GKTGVNSGVML.NMTRMR.K.F.NDMTTV..QW.DILM..LKKYKL.IT..GDQ.LLNIMF.HNPES
Retrocopy P*CGKTGVNSGVMLTNMTRMRMKCFENDMTTV*IQWEDILMTWLKKYKLDITG<GDQNLLNIMFLHNPES

Parental  LFVFPCQWNYRPDHCIYGSNCQEAEEEGIFILHGNRGVYHDDKQPAFRAVYEALRNCSFE-DDNIRSLLK
          LFVFP.QW...PDH..YGS.CQEA.EEGIFILHGNRGVYHDDKQPAFRAVYEALRNCSF..DDN..SL.K
Retrocopy LFVFPRQWKCHPDHTLYGSSCQEA-EEGIFILHGNRGVYHDDKQPAFRAVYEALRNCSFK<DDNVHSLIK

Parental  PLELELQKTVHTYCGKIYKIFIKQLAKSVRDRYARSPKEK
          PLELELQ.TVHTY.GKIYKIFIKQLAKSVRD.YARSPKE.
Retrocopy PLELELQITVHTYRGKIYKIFIKQLAKSVRDCYARSPKER

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.72 RPM
SRP007412_cerebellum	0.00 RPM	1.26 RPM
SRP007412_heart	0.00 RPM	0.41 RPM
SRP007412_kidney	0.00 RPM	1.47 RPM
SRP007412_liver	0.00 RPM	1.64 RPM
SRP007412_testis	0.00 RPM	3.94 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1950 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1950 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 8 parental genes, and 19 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000151233	5 retrocopies	retro_hsap_2295, retro_hsap_4167, retro_hsap_4177, retro_hsap_4258, retro_hsap_4267,
Gorilla gorilla	ENSGGOG00000027928	3 retrocopies	retro_ggor_1702, retro_ggor_1950 , retro_ggor_2798,
Monodelphis domestica	ENSMODG00000008913	1 retrocopy	retro_mdom_512,
Mus musculus	ENSMUSG00000036197	1 retrocopy	retro_mmus_2325,
Nomascus leucogenys	ENSNLEG00000017947	1 retrocopy	retro_nleu_2700,
Pongo abelii	ENSPPYG00000004419	2 retrocopies	retro_pabe_1849, retro_pabe_1976,
Pan troglodytes	ENSPTRG00000004836	5 retrocopies	retro_ptro_1623, retro_ptro_2832, retro_ptro_2960, retro_ptro_3006, retro_ptro_848,
Rattus norvegicus	ENSRNOG00000005234	1 retrocopy	retro_rnor_2754,