RetrogeneDB ID: retro_ggor_205

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:102929709..102930087(+)
• Located in intron of: ENSGGOG00000013617

Retrocopy information

• Ensembl ID: ENSGGOG00000028277
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: BRI3
• Ensembl ID: ENSGGOG00000009646
• Aliases: None
• Description: None

Sequence

>retro_ggor_205
ATGGACCACAAGACTCTGCTGCAGGAGCGGCCGCCCGCCTACAACCTGGAGGCCGGCCAGGGCGACTACGCGTGCGGCCC
GCACGGCTACGGCGCCATGCCCGCCGCGCCCCCGCAACCGCCCTACTCCTACCTCGTCACACGGACACCCACCCACCATC
CCAGGGTCTACAACATCCACAGCCGGACCATCACCCGCTATCCTACCAACTCTATCGTGGTCGTGGGAGGCTGTCCCGTC
TGCAGGGTCGGGGGGCTGCAGGACTGCTTCACCTTCCTGGGCATCTTCCTGGCCATCATCCTGTTCCCCTTTGGGTTCAT
CTGCTGTTTTGCCTTGAGGAAGCGAAGATGCCCCAACTGTGGAGCCACCTTCGCTTAA

Alignment

ORF - retro_ggor_205 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 90.53 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  GAIPAAPPPPPYPYLVTGIPTHHPRVYNIHSRTVTRYPANSIVVVGGCPVCRVGVLEDCFTFLGIFLAII
          GA.PAAPP.PPY.YLVT..PTHHPRVYNIHSRT.TRYP.NSIVVVGGCPVCRVG.L.DCFTFLGIFLAII
Retrocopy GAMPAAPPQPPYSYLVTRTPTHHPRVYNIHSRTITRYPTNSIVVVGGCPVCRVGGLQDCFTFLGIFLAII

Parental  LFPFGFICCFALRKRRCPNCGATFA
          LFPFGFICCFALRKRRCPNCGATFA
Retrocopy LFPFGFICCFALRKRRCPNCGATFA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.10 RPM	15.01 RPM
SRP007412_cerebellum	0.08 RPM	11.94 RPM
SRP007412_heart	0.44 RPM	28.08 RPM
SRP007412_kidney	0.08 RPM	37.86 RPM
SRP007412_liver	0.11 RPM	37.54 RPM
SRP007412_testis	0.31 RPM	35.85 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_205 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_205 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_195
Pongo abelii	retro_pabe_50

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Parental genes homology:

Parental genes homology involve 9 parental genes, and 15 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000015227	1 retrocopy	retro_cjac_2527,
Homo sapiens	ENSG00000164713	3 retrocopies	retro_hsap_1095, retro_hsap_1811, retro_hsap_195,
Gorilla gorilla	ENSGGOG00000009646	1 retrocopy	retro_ggor_205 ,
Microcebus murinus	ENSMICG00000002888	1 retrocopy	retro_mmur_372,
Macaca mulatta	ENSMMUG00000013275	2 retrocopies	retro_mmul_1248, retro_mmul_849,
Otolemur garnettii	ENSOGAG00000000638	1 retrocopy	retro_ogar_63,
Pongo abelii	ENSPPYG00000025815	3 retrocopies	retro_pabe_1484, retro_pabe_50, retro_pabe_910,
Pan troglodytes	ENSPTRG00000019436	1 retrocopy	retro_ptro_698,
Tursiops truncatus	ENSTTRG00000015705	2 retrocopies	retro_ttru_706, retro_ttru_91,