RetrogeneDB ID: retro_ggor_432

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:123245579..123246074(-)
• Located in intron of: ENSGGOG00000004007

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: NAA50
• Ensembl ID: ENSGGOG00000006589
• Aliases: None
• Description: None

Sequence

>retro_ggor_432
CGGATCGAGCTAGGAGATGTGACACCACACAATATTAAACAGTTGAAAAGATTGAATCAGGTCATCTTTCCAGTCAGCTA
CAATGGCAAGTTCTACAAGGATGTGCTGGAGGTTGGCGAGCTAGCAAAACTTGCCTATTTCAATGATATTGCTGTAGGTG
CGGTATGCTGTAGGGTGGATCATTCACAGAATCAGAAGAGACTTTACATCATGACACTAGGATGTCTGGCACCTTACCGA
AGGCTAGGAATAGGAACTAAAATGTTAAATCATGTCTTAAACATCTGTGAAAAAGATGGTACTTTTGACAACATTTATCT
GCATGTCCAGATCAGCAATGAGTCGGCAATTGACTTCTACAGGAAGTTTGGCTTTGAGATTATTGAGACAAAGAAGAACT
ACTATAAGAGGATAGAGCCCGCAGATGCTCATGTGCTGCAGAAAAACCTCAAAGTTCCTTCTCGTCAGAATGCAGATGTG
CAAAAGACAGACAAC

Alignment

ORF - retro_ggor_432 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 98.79 %
• Parental protein coverage: 97.63 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  RIELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVLEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYI
          RIELGDVTPHNIKQLKRLNQVIFPVSYN.KFYKDVLEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYI
Retrocopy RIELGDVTPHNIKQLKRLNQVIFPVSYNGKFYKDVLEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYI

Parental  MTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEIIETKKNYYKRIEP
          MTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEIIETKKNYYKRIEP
Retrocopy MTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEIIETKKNYYKRIEP

Parental  ADAHVLQKNLKVPSGQNADVQKTDN
          ADAHVLQKNLKVPS.QNADVQKTDN
Retrocopy ADAHVLQKNLKVPSRQNADVQKTDN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.24 RPM	13.52 RPM
SRP007412_cerebellum	0.39 RPM	10.01 RPM
SRP007412_heart	0.09 RPM	4.16 RPM
SRP007412_kidney	0.61 RPM	10.92 RPM
SRP007412_liver	0.34 RPM	5.75 RPM
SRP007412_testis	1.04 RPM	25.07 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_432 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_432 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 7 parental genes, and 15 retrocopies.

Species	Parental gene accession	Retrocopies number
Cavia porcellus	ENSCPOG00000014169	6 retrocopies	retro_cpor_1027, retro_cpor_1028, retro_cpor_1199, retro_cpor_1200, retro_cpor_217, retro_cpor_480,
Gorilla gorilla	ENSGGOG00000006589	2 retrocopies	retro_ggor_432 , retro_ggor_710,
Loxodonta africana	ENSLAFG00000004023	1 retrocopy	retro_lafr_1159,
Oryctolagus cuniculus	ENSOCUG00000006467	2 retrocopies	retro_ocun_466, retro_ocun_984,
Otolemur garnettii	ENSOGAG00000011197	1 retrocopy	retro_ogar_157,
Procavia capensis	ENSPCAG00000009780	2 retrocopies	retro_pcap_205, retro_pcap_459,
Ictidomys tridecemlineatus	ENSSTOG00000009438	1 retrocopy	retro_itri_1703,