RetrogeneDB ID: retro_lcha_125

Retrocopy location

• Organism: Coelacanth (Latimeria chalumnae)
• Coordinates: JH130685.1:68673..69141(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSLACG00000013075
• Aliases: None
• Description: None

Sequence

>retro_lcha_125
AAAATCTGCCTCTACATGGATGATGTCCTGCTTCTGATACGAGACCCTGTGGAATCGATTCCAGCTTTATTGGAAATAAT
CGGAACATTTGGGGCCATTTCTGGGTTCAAAGTAAACTGGGCAAAATCAGAGGTGATGCCTCTTAATGTGCATTGTACCT
AACAAGACCATCAGGAATTCCCCTTTGTGGTTAAAGCGCAGTACATAAAATATTTAGGAACTAGACTCACAGCTTCTTTT
GACAAACTATTCTATGAAAACGGCCTGTGTATTCTAAAAGAGGTCAAAGAAGACCTTGATAGATGGCAGCATCTCCCCCT
TTCATTGTGGGTTAGAGTAGATATCATAAAAATGAATATCTTACCTTGGTTGCTGTATGTGGTGGCCTCCGTCCCTGTAG
AAATCCCCCACTCTTGGTTTCAGCAGATAAGAACCCTCTTTCTGAAGTTTATGTGGAACACTAAAAAA

Alignment

ORF - retro_lcha_125 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 51.92 %
• Parental protein coverage: 65.92 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  KMRLYANNTLLTLTQS-ESIPVFMRIIDQYHILAIFKINWNKSEILPLNIQC---NISKFPFE-KKHYLK
          K..LY....LL......ESIP....II........FK.NW.KSE..PLN..C.......FPF..K..Y.K
Retrocopy KICLYMDDVLLLIRDPVESIPALLEIIGTFGAISGFKVNWAKSEVMPLNVHCT*QDHQEFPFVVKAQYIK

Parental  YLGIRLSSSFKELFKENGPTILKEIKEDLDRRHNLPLII----DTIKMNILFRLLYVVTSVPVGFPSQWF
          YLG.RL..SF..LF.ENG..ILKE.KEDLDR...LPL......D.IKMNIL..LLYVV.SVPV..P..WF
Retrocopy YLGTRLTASFDKLFYENGLCILKEVKEDLDRWQHLPLSLWVRVDIIKMNILPWLLYVVASVPVEIPHSWF

Parental  QQVRTAFIKFIWRGTK
          QQ.RT.F.KF.W...K
Retrocopy QQIRTLFLKFMWNTKK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
DRP000627_gill	0.00 RPM	0.07 RPM
DRP000627_kidney	0.00 RPM	0.14 RPM
DRP000627_pectoral_fin	0.00 RPM	0.00 RPM
DRP000627_pelvic_fin	0.00 RPM	0.00 RPM
DRP000627_pharynx	0.00 RPM	0.09 RPM
DRP000627_tail_muscle	0.00 RPM	0.02 RPM

ChIP-Seq

Latimeria chalumnae was not studied using ChIP-Seq data.

EST

Latimeria chalumnae was not studied using EST data.

TSS

Latimeria chalumnae was not studied using FANTOM5 data.

Lab

retro_lcha_125 was not experimentally validated.

Homology

Retrocopy orthology:

Latimeria chalumnae does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 1 parental gene, and 4 retrocopies.

Species	Parental gene accession	Retrocopies number
Latimeria chalumnae	ENSLACG00000013075	4 retrocopies	retro_lcha_105, retro_lcha_116, retro_lcha_125 , retro_lcha_98,