RetrogeneDB ID: retro_mdom_1858

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 8:120114430..120114878(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMODG00000018440
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: DUT
• Ensembl ID: ENSMODG00000002687
• Aliases: None
• Description: deoxyuridine triphosphatase [Source:HGNC Symbol;Acc:3078]

Sequence

>retro_mdom_1858
GCACAGCAAGAGAAGGAGACTTACATGTGCCTTTGCTTCACCTGCCTCTCTGAGCATGCCACTGTCCCTTCTAAGGAGTC
GGCCCTGGGCTGCTGGCTATGACTTGTACAGTGCCTATGATTATACAATACCAGCCATGGAGAAAGCCCTTGTGAAAACT
GATATTCAGATTCCTCTTCCTCCTGGCTGTTATGGTCGAGTTGCTCCACATTCTGCCTTGGCTACAAAACACTTCATAGA
TGTAGGAGCTGGTGTCATAGATGAAGATTACGGAGGAAATGTTGGTGTAGTGCTATTTAATTTTGGCAAAGAAACCTTTG
AAGTAAAAAAGGGTGACCGGATTGCACAGCTGATTTGTGAATGGGTTTTTTATCCAGAACTTGAAGAAGTCCAAGGCTTA
GATGACACTGAACGTGGATCGGGAGGTTTTGGTTCTACTGGTCAAAAC

Alignment

ORF - retro_mdom_1858 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 86. %
• Parental protein coverage: 88.55 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  AQQEEGTPVRLRFARLSEHATAPSKGSAR-AAGYDF--AYDYTIPAMEKALVKTDIQISLPPGCYGRVAP
          AQQE..T...L.F..LSEHAT.PSK.SA..AAGYD...AYDYTIPAMEKALVKTDIQI.LPPGCYGRVAP
Retrocopy AQQEKETYMCLCFTCLSEHATVPSKESAL>AAGYDLYSAYDYTIPAMEKALVKTDIQIPLPPGCYGRVAP

Parental  RSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKETFEVKKGDRIAQLICERVFYPELEEVQGLDDTERG
          .S.LA.KHFIDVGAGVIDEDY.GNVGVVLFNFGKETFEVKKGDRIAQLICE.VFYPELEEVQGLDDTERG
Retrocopy HSALATKHFIDVGAGVIDEDYGGNVGVVLFNFGKETFEVKKGDRIAQLICEWVFYPELEEVQGLDDTERG

Parental  SGGFGSTGQN
          SGGFGSTGQN
Retrocopy SGGFGSTGQN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	30.04 RPM
SRP007412_cerebellum	0.00 RPM	30.36 RPM
SRP007412_heart	0.00 RPM	21.33 RPM
SRP007412_kidney	0.00 RPM	28.97 RPM
SRP007412_liver	0.00 RPM	12.08 RPM
SRP007412_testis	0.00 RPM	22.39 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_1858 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_1858 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 24 parental genes, and 78 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000001873	1 retrocopy	retro_amel_1411,
Bos taurus	ENSBTAG00000011998	3 retrocopies	retro_btau_1765, retro_btau_510, retro_btau_60,
Callithrix jacchus	ENSCJAG00000001813	2 retrocopies	retro_cjac_1014, retro_cjac_2008,
Dasypus novemcinctus	ENSDNOG00000024791	8 retrocopies	retro_dnov_204, retro_dnov_2096, retro_dnov_2230, retro_dnov_225, retro_dnov_2270, retro_dnov_2608, retro_dnov_528, retro_dnov_639,
Dipodomys ordii	ENSDORG00000010560	1 retrocopy	retro_dord_146,
Equus caballus	ENSECAG00000015971	1 retrocopy	retro_ecab_375,
Felis catus	ENSFCAG00000015350	3 retrocopies	retro_fcat_1158, retro_fcat_33, retro_fcat_937,
Homo sapiens	ENSG00000128951	6 retrocopies	retro_hsap_1698, retro_hsap_256, retro_hsap_2699, retro_hsap_2963, retro_hsap_3624, retro_hsap_4771,
Gorilla gorilla	ENSGGOG00000005658	5 retrocopies	retro_ggor_1272, retro_ggor_1453, retro_ggor_2053, retro_ggor_2974, retro_ggor_306,
Macropus eugenii	ENSMEUG00000006318	3 retrocopies	retro_meug_1739, retro_meug_2104, retro_meug_476,
Myotis lucifugus	ENSMLUG00000006842	2 retrocopies	retro_mluc_1550, retro_mluc_487,
Macaca mulatta	ENSMMUG00000016898	6 retrocopies	retro_mmul_1429, retro_mmul_2645, retro_mmul_449, retro_mmul_707, retro_mmul_720, retro_mmul_910,
Monodelphis domestica	ENSMODG00000002687	3 retrocopies	retro_mdom_1606, retro_mdom_1858 , retro_mdom_693,
Nomascus leucogenys	ENSNLEG00000005996	2 retrocopies	retro_nleu_2602, retro_nleu_859,
Oryctolagus cuniculus	ENSOCUG00000003862	1 retrocopy	retro_ocun_798,
Otolemur garnettii	ENSOGAG00000028847	7 retrocopies	retro_ogar_1207, retro_ogar_1422, retro_ogar_1500, retro_ogar_1653, retro_ogar_2348, retro_ogar_2815, retro_ogar_3485,
Pongo abelii	ENSPPYG00000006454	2 retrocopies	retro_pabe_3820, retro_pabe_3831,
Pan troglodytes	ENSPTRG00000007044	2 retrocopies	retro_ptro_216, retro_ptro_3177,
Rattus norvegicus	ENSRNOG00000007221	1 retrocopy	retro_rnor_859,
Sus scrofa	ENSSSCG00000026096	3 retrocopies	retro_sscr_1121, retro_sscr_122, retro_sscr_175,
Ictidomys tridecemlineatus	ENSSTOG00000007811	1 retrocopy	retro_itri_125,
Tarsius syrichta	ENSTSYG00000012669	9 retrocopies	retro_tsyr_1044, retro_tsyr_1236, retro_tsyr_1251, retro_tsyr_1825, retro_tsyr_1991, retro_tsyr_215, retro_tsyr_616, retro_tsyr_747, retro_tsyr_771,
Tursiops truncatus	ENSTTRG00000015422	2 retrocopies	retro_ttru_1834, retro_ttru_585,
Vicugna pacos	ENSVPAG00000004723	4 retrocopies	retro_vpac_213, retro_vpac_32, retro_vpac_527, retro_vpac_612,