RetrogeneDB ID: retro_mmul_19

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 1099214270388:345..666(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMMUG00000012258
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: BIRC5
• Ensembl ID: ENSMMUG00000013767
• Aliases: None
• Description: baculoviral IAP repeat-containing protein 5 [Source:RefSeq peptide;Acc:NP_001253110]

Sequence

>retro_mmul_19
ATGGGTTCCCCGACGTTGCCCCCTGCCTGGCAGCCCTTTCTCAAGGACCACCGCATCTCTACATTCAAGAACTGGCCCTT
CTTGGAGGGCTGCGCCTGCACCCTGGAGCGGATGGCTGAGGCTGGCTTCATCCACTGCCCCACTGAGAACAAGCCAGACT
TGGCCCAGTGTTTCTTCTGCTTCAAGGAGCTGGAAGGCTGGGAGCCAGATGACGACCCCATAGAGGAACATAAAAAGCAT
TCATCCGATTGCGCTTTCCTTTCTGTCAAGAAGCAGTTTGAAGAATTAACCCTCGGTGAATTTTTGAAACTGGACAGAGA
A

Alignment

ORF - retro_mmul_19 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 96.26 %
• Parental protein coverage: 75.35 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPD
          MG.PTLPPAWQPFLKDHRISTFKNWPFLEGCACT.ERMAEAGFIHCPTEN.PDLAQCFFCFKELEGWEPD
Retrocopy MGSPTLPPAWQPFLKDHRISTFKNWPFLEGCACTLERMAEAGFIHCPTENKPDLAQCFFCFKELEGWEPD

Parental  DDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRE
          DDPIEEHKKHSS.CAFLSVKKQFEELTLGEFLKLDRE
Retrocopy DDPIEEHKKHSSDCAFLSVKKQFEELTLGEFLKLDRE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.11 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.16 RPM
SRP007412_cerebellum	0.00 RPM	0.06 RPM
SRP007412_heart	0.00 RPM	0.06 RPM
SRP007412_kidney	0.00 RPM	0.12 RPM
SRP007412_liver	0.00 RPM	0.16 RPM
SRP007412_testis	0.04 RPM	16.89 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_19 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_19 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_19 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 6 parental genes, and 7 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000013573	1 retrocopy	retro_btau_1347,
Cavia porcellus	ENSCPOG00000027390	1 retrocopy	retro_cpor_1355,
Equus caballus	ENSECAG00000008466	1 retrocopy	retro_ecab_100,
Myotis lucifugus	ENSMLUG00000006281	1 retrocopy	retro_mluc_254,
Macaca mulatta	ENSMMUG00000013767	1 retrocopy	retro_mmul_19 ,
Monodelphis domestica	ENSMODG00000001871	2 retrocopies	retro_mdom_307, retro_mdom_996,