RetrogeneDB ID: retro_mmul_791

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 11:10810996..10811455(+)
• Located in intron of: ENSMMUG00000015484

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: mml-mir-762-3
• Ensembl ID: ENSMMUG00000003225
• Aliases: None
• Description: mml-mir-762-1 [Source:miRBase;Acc:MI0012548]

Sequence

>retro_mmul_791
ATGGCCGGCCGGACCGTACGGGCCGAGACCCGGAGCCGGGCCGAAGATAACATCAAGAAGGTAATGGCGACCATCAAGAA
GGTCCAAAAATGGAAGAAGCAATGAGTGACTGTAGGCGACACTTCCCTTCGTATCTTCAAGTAAGTGCCAGTGGTGGACC
CCCAGGAGGAGGAACGAAGGCGGGCAGGTGGCGGGGCAAAGAGATCCCGTGGCCGGGAACGTCGGGGCAGGGGCGCCAGT
CCCCGAGGGGGTGGCCCTCTCATCCTGCTGGATCTCAATGATGAGAACAGCAACCAGAGTTTCCATTCGGAAAGTTCCCT
GCAAAAAGGCACAGAGCCCAGTCCTGAGGGCAGCCCCCAGCCCAGCCGCCCTGTGTCACCTGCCGGACCCCCAGAAGGGG
TCCCTAAAGAGGCTCAGCCCCCACGGCTGGGCCAAGAAAAAAATCCCGGGGGCATAACT

Alignment

ORF - retro_mmul_791 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.54 %
• Parental protein coverage: 63.22 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERRRAGGGAERSR
          MAGRTVRAETRSRA.D.IKKVMATI.KV..W.K..VTVGDTSLRIFK.VPVVDPQEEERRRAGGGA.RSR
Retrocopy MAGRTVRAETRSRAEDNIKKVMATIKKVQKWKKQ*VTVGDTSLRIFK*VPVVDPQEEERRRAGGGAKRSR

Parental  GRERRGRGASPRGGGPLILLDLNDENSNQSFHSEGSLQKGTEPSPGGTPQPSRPVSPAGPPEGVPEEAQP
          GRERRGRGASPRGGGPLILLDLNDENSNQSFHSE.SLQKGTEPSP.G.PQPSRPVSPAGPPEGVP.EAQP
Retrocopy GRERRGRGASPRGGGPLILLDLNDENSNQSFHSESSLQKGTEPSPEGSPQPSRPVSPAGPPEGVPKEAQP

Parental  PRLGQERDPGGIT
          PRLGQE..PGGIT
Retrocopy PRLGQEKNPGGIT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	1.34 RPM	2.47 RPM
SRP007412_brain_prefrontal_cortex	1.98 RPM	9.84 RPM
SRP007412_cerebellum	0.45 RPM	2.26 RPM
SRP007412_heart	2.77 RPM	9.13 RPM
SRP007412_kidney	2.58 RPM	7.28 RPM
SRP007412_liver	0.87 RPM	5.11 RPM
SRP007412_testis	0.11 RPM	30.46 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_791 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_791 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_791 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 8 parental genes, and 21 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000007604	2 retrocopies	retro_amel_1090, retro_amel_1613,
Bos taurus	ENSBTAG00000008412	1 retrocopy	retro_btau_618,
Canis familiaris	ENSCAFG00000016715	1 retrocopy	retro_cfam_898,
Dipodomys ordii	ENSDORG00000001676	1 retrocopy	retro_dord_517,
Equus caballus	ENSECAG00000000482	1 retrocopy	retro_ecab_704,
Felis catus	ENSFCAG00000029090	1 retrocopy	retro_fcat_1969,
Macaca mulatta	ENSMMUG00000003225	13 retrocopies	retro_mmul_1247, retro_mmul_1613, retro_mmul_1818, retro_mmul_2108, retro_mmul_2153, retro_mmul_2644, retro_mmul_390, retro_mmul_724, retro_mmul_740, retro_mmul_750, retro_mmul_755, retro_mmul_791 , retro_mmul_975,
Mustela putorius furo	ENSMPUG00000011988	1 retrocopy	retro_mputfur_954,