RetrogeneDB ID: retro_mmur_1086

Retrocopy location

• Organism: Mouse Lemur (Microcebus murinus)
• Coordinates: scaffold_21191:8305..9921(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: DNMT3A
• Ensembl ID: ENSMICG00000004108
• Aliases: None
• Description: DNA (cytosine-5-)-methyltransferase 3 alpha [Source:HGNC Symbol;Acc:2978]

Sequence

>retro_mmur_1086
GTGGCCAGCAGCCGCTCCGGGAAGCTGTTCCCAGCGTGCCATGACAGCGACGAGAGTGACACTGCCAAGGCCGTGGAGGT
GCAGAACAAGCAAATGATTGAATGGGCCCTCGGGGGGGGTTCCAGTCCTCCGGCCCCAAGGCCCTGGAGCCACCAGAAGA
GGAGAAGAATCCCTACAAAGAAGTTTACACAGACATGTGGGTTGAACCTGAGGCAGCTGCCTATGCACCACCCCCACCAG
CCAAAAAGCCCCGAAAGAGCACAACAGAGAAGCCCAAGGTCAAGGAGATTATCGATGAACTCACAAGAGAGCGGCTGGTG
TACGAGGTGCGGCAGAAGTGCCGGAATATCGAAGATATTTGCATTTCTTGTGGGAGCCTCAACGTCACCCTGGAACACCC
TCTCTTCATTGGAGGAATGTGCCAAAACTGCAAGAACTGCTTCCTGGAGTGTGCATACCAGTATGACGACGATGGCTATC
AGTCCTACTGCACCAGCTGCTGTGGGGGGCGTGAGGTGCCCATGTGCGGGAACAACAACTGCTGCAGGTGCTTTTGCGTG
GAGTGTGTGGACCTCTTGGTGGGGCCAGGGGCTGCCCAGGCGGCCATTAAGGAAGACCCCTGGAACTGCTACATATGTGG
GCACAAGGGTACCTATGGGCTGCTGCGGCGGCGGGACAACTGGCCCTCTAGGCTCCAGATGTTCTTCGCCAATAACCACA
ACCAGGAATTTGACCCTCCGAAGGTTTATCCACCTGTCCCAGCCGAGAAGAGGAAGCCTATCCGGGTGCTGTCTCTCTTT
GACGGAATTGCTACAGGGCTCCTGGTGCTGAAGGACCTGGGCATCCAGGTGGACCGCTACATTGCCTCGGAGGTGTGCGA
GGACTCCATCACGGTGGGCATGGTGCGACACCAGGGGAAGATCATGTACGTCGGGGATGTCCGCAGCGTCACACAGAAGC
ATATCTAGGAGTGGGGCCCATTCGATCTGGTGATTGGGGGCAGTCCCTGCAACGATCTCTCCATCGTCAACCCTGCCCAC
AAGGGACTCTACAAGGGCACTGGCCAGCTCTTCTTTGAGTTCTACCGCCTCCTGCATGATGCGTGGCCCAAGGAGGGAGA
TGATCGCCCCTTCTTCTAGCTCTTTGAGAATGTGGTGGCCATGGGCGTTAGTGACAAGAGGGACATCGCGAGATTTCTCG
AGTCCAACCCTGTGATGATTGATACCAAAGAAATGTCAGCTGCACACAGGGCCCGCTACTTTTGGGGTAACCTTCCCGGT
ATGAACAGGCCATTGGCATCCACTGTGAATGATAAGCTGGAGCTGCAGGAGTGTCTGGAGCACGGCAGGATAGCCAAGTT
CAGCAAAGTAAGGACCATTACTACTAGGTCGAACTCCATAAAGCAGGGCAAAGACCAGCATTTCCCCGTCTTCATGAACG
AGAAAGAGGACATCTTATGGTGCACTGAAATGGAAAGGGTGTTTGGCTTCCCCGTCCACTATACCGACGTCTCCAACATG
AGTCGCTTGGCCAGGCAGAGACTTCTGGGCCGGTCGTGGAGCGTGCCAGTCATCCGCCACCTCTTCGCTCCGCTGAAGGA
ATATTTTGCTTGTGTG

Alignment

ORF - retro_mmur_1086 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 95.56 %
• Parental protein coverage: 58.86 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  VASSRSGKLFPACHDSDESDTAKAVEVQNKQMIEWALGGF-QPSGP-KGLEPPEEEKNPYKEVYTDMWVE
          VASSRSGKLFPACHDSDESDTAKAVEVQNKQMIEWAL.....P..P.K.LEPPEEEKNPYKEVYTDMWVE
Retrocopy VASSRSGKLFPACHDSDESDTAKAVEVQNKQMIEWALXXXSSPPAP<KALEPPEEEKNPYKEVYTDMWVE

Parental  PEAAAYAPPPPAKKPRKSTTEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFIGG
          PEAAAYAPPPPAKKPRKSTTEKPKVKEIIDE.TRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFIGG
Retrocopy PEAAAYAPPPPAKKPRKSTTEKPKVKEIIDELTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFIGG

Parental  MCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWN
          MCQNCKNCFLECAYQYDDDGYQSYCT.CCGGREV.MCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWN
Retrocopy MCQNCKNCFLECAYQYDDDGYQSYCTSCCGGREVPMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWN

Parental  CYMCGHKGTYGLLRRRDDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKD
          CY.CGHKGTYGLLRRRD.WPSRLQMFFANNH.QEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKD
Retrocopy CYICGHKGTYGLLRRRDNWPSRLQMFFANNHNQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKD

Parental  LGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKG
          LGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHI.EWGPFDLVIGGSPCNDLSIVNPA.KG
Retrocopy LGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHI*EWGPFDLVIGGSPCNDLSIVNPAHKG

Parental  LYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRAR
          LY.GTG.LFFEFYRLLHDA.PKEGDDRPFF.LFENVVAMGVSDKRDI.RFLESNPVMID.KE.SAAHRAR
Retrocopy LYKGTGQLFFEFYRLLHDAWPKEGDDRPFF*LFENVVAMGVSDKRDIARFLESNPVMIDTKEMSAAHRAR

Parental  YFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCT
          YFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCT
Retrocopy YFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCT

Parental  EMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV
          EMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV
Retrocopy EMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Microcebus murinus was not studied using RNA-Seq expression data.

ChIP-Seq

Microcebus murinus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmur_1086 retrocopy.

TSS

Microcebus murinus was not studied using FANTOM5 data.

Lab

retro_mmur_1086 was not experimentally validated.

Homology

Retrocopy orthology:

Microcebus murinus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 6 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000008172	2 retrocopies	retro_cjac_4163, retro_cjac_899,
Microcebus murinus	ENSMICG00000004108	2 retrocopies	retro_mmur_1086 , retro_mmur_797,
Monodelphis domestica	ENSMODG00000015850	1 retrocopy	retro_mdom_859,
Oryctolagus cuniculus	ENSOCUG00000024688	1 retrocopy	retro_ocun_564,