RetrogeneDB ID: retro_ggor_1091

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 14:20348225..20348702(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: DSCR6
• Ensembl ID: ENSGGOG00000006091
• Aliases: None
• Description: None

Sequence

>retro_ggor_1091
CCCTGGGGACCATCTCCAGCATGGAGCCTCACAGCGTGGAGAGCTGTGATCCTGACACCTGCAGATGCTGAGCTGACCAG
AACTGGAAGCCAGTTTAAACCTGGGGGAGATCAAGAAACTTTTGGATTAAAGGAAGTCTTCAGGTTTCAGCATCCTGTAA
GACTTTACTTACCCTTTTTGAAATGTCAAGAATATTTGCAGTGTTCTGGGGAAAAAGTGCTGGTCGGTTTTCCAGTGCAA
GCCATGATATACTTCTATAACGATGAGTCTGATTCAGATGATGAAGAGCAAGAGGAAGAAACTAGCTCTTCCATTTTCTG
TGCCAGGAGGTGGAAGGTCTGGAGGAAAATGTCCTCTGGGGGAAAGGGCAGAGACAGGATCATAAACTGAGGATGGCAAT
CTGAAAGAAGGGGTGGCCTCTGTGTGGAGGACCAGCTCCCCTGAGGTGACTCCTCAAGGGGCAGGGAGTGCTCCTCA

Alignment

ORF - retro_ggor_1091 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 54.88 %
• Parental protein coverage: 85.26 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  PPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFGSKGAFGFQHPVRVYLPMSKRQEYLRSSG
          P..P....S...WR..I.TP.DAELTRTG....P..DQ.TFG.K..F.FQHPVR.YLP..K.QEYL..SG
Retrocopy PWGPSPAWSLTAWRAVILTPADAELTRTGSQFKPGGDQETFGLKEVFRFQHPVRLYLPFLKCQEYLQCSG

Parental  EQVLASFPVQATIDFYDDESTESASEAEEPEEGPPP-LHLLPQEVGGLQEN-GPGGKGRDQGINQGQRSS
          E.VL..FPVQA.I.FY.D...ES.S..EE.EE......H.L.QEV.GL.EN...GGKGRD..IN.G..S.
Retrocopy EKVLVGFPVQAMIYFYND---ESDSDDEEQEEETSS<FHFLCQEVEGLEEN>SSGGKGRDRIIN*GWQSE

Parental  GGGDHWGEGPLPQGVSSRGGKCSS
          ..G....E..LP.G.SSRG..CSS
Retrocopy RRGGLCVEDQLP*GDSSRGRECSS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.04 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.20 RPM
SRP007412_liver	0.00 RPM	0.13 RPM
SRP007412_testis	0.00 RPM	0.10 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1091 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1091 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1407
Pan troglodytes	retro_ptro_964
Pongo abelii	retro_pabe_1163

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Parental genes homology:

Parental genes homology involve 6 parental genes, and 6 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000036019	1 retrocopy	retro_btau_1393,
Homo sapiens	ENSG00000183145	1 retrocopy	retro_hsap_1407,
Gorilla gorilla	ENSGGOG00000006091	1 retrocopy	retro_ggor_1091 ,
Nomascus leucogenys	ENSNLEG00000004521	1 retrocopy	retro_nleu_1423,
Pongo abelii	ENSPPYG00000011408	1 retrocopy	retro_pabe_1163,
Pan troglodytes	ENSPTRG00000013896	1 retrocopy	retro_ptro_964,