RetrogeneDB ID: retro_ggor_1842

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 3:37998218..37998550(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PRADC1
• Ensembl ID: ENSGGOG00000007761
• Aliases: None
• Description: None

Sequence

>retro_ggor_1842
TCAGCAGGTTTCTTCATCCAGGACCAGATCGCTCTGGTGGAGAGTGGGGGCTGCTCCCTCCTCTCCAAGACTCGGGTGGT
CCAAGAGCATGGCGGGCGGGCCGTGATCATCTCTGACAATGCGGTTGACAATGACAGCTTCTATGTGGCGATGATCCAGG
ACAGTACCCAGCGCACAGCTGACATCTCCGCCCTCTTTCTTCTCAGCCGAGAGGCTACATGATCCGCCGCTCCCTGGAAC
AGCCTGGGCTGCCATGGGCCATCATTTCCATCCCAGTCAATGTCACCAGTATCCCCACCTTTGAGCTGCAGCAACCATCC
TGGTCCTTCTGG

Alignment

ORF - retro_ggor_1842 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.29 %
• Parental protein coverage: 59.04 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  SNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGR
          S.GFFIQDQIALVE.GGCS.LSKTRVVQEHGGRAVIISDNAVDNDSFYV.MIQDSTQRTADI.ALFLL.R
Retrocopy SAGFFIQDQIALVESGGCSLLSKTRVVQEHGGRAVIISDNAVDNDSFYVAMIQDSTQRTADISALFLLSR

Parental  D-GYMIRRSLEQHGLPWAIISIPVNVTSIPTFELLQPPWTFW
          ..GYMIRRSLEQ.GLPWAIISIPVNVTSIPTFEL.QP.W.FW
Retrocopy E<GYMIRRSLEQPGLPWAIISIPVNVTSIPTFELQQPSWSFW

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	8.58 RPM
SRP007412_cerebellum	0.08 RPM	6.78 RPM
SRP007412_heart	0.00 RPM	29.24 RPM
SRP007412_kidney	0.04 RPM	13.53 RPM
SRP007412_liver	0.08 RPM	20.05 RPM
SRP007412_testis	0.00 RPM	9.84 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1842 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1842 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2633
Pan troglodytes	retro_ptro_1777

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Parental genes homology:

Parental genes homology involve 5 parental genes, and 5 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000135617	1 retrocopy	retro_hsap_2633,
Gorilla gorilla	ENSGGOG00000007761	1 retrocopy	retro_ggor_1842 ,
Pan troglodytes	ENSPTRG00000012059	1 retrocopy	retro_ptro_1777,
Sorex araneus	ENSSARG00000003050	1 retrocopy	retro_sara_205,
Tarsius syrichta	ENSTSYG00000003210	1 retrocopy	retro_tsyr_1717,