RetrogeneDB ID: retro_ggor_199

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 6:98953855..98954593(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000024853
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: ENSG00000164039
• Ensembl ID: ENSGGOG00000006381
• Aliases: None
• Description: None

Sequence

>retro_ggor_199
ATGGGTCGACTTGATGGGAAAGTCATCATCCTGACGGCCGCTGCTCAGGGGATTGGCCAAGCAGCTGCCTTAGCTTTTGT
AAGAGAAGGTGCCAAAGTCATAGCCACAGACATTAATGTGTCCAAACTTCAGGAACTGGAAAAGTACCCGGGTATTCAAA
CTCGTGTCCTTGATGTTACAAAGAAGAAACAAATTGATCAGTTCGCCAATGAAGTTGAGAGACTTGATGTTCTCTTTAAT
GTTGCTGGTTTTGTCCATCATGAAACTGTCCTGGATTGTGAGAAGAAAGACTGGGACTTCTCGATGAATCTCAATGTGCA
CAGCACGTACCTGATGATCAAGGCATTCCTTCCTAAAATGCTTGCTCAAAAATCTGGCAATATTATCACCATGTCTTCTG
TGGTTTCCAGCATCAAAGGAGTTGTGAACAGATGTGTGTACAGCACAACCAAGGCAGCCGTGATTGGCCTCACAAAATCT
GTGGCTGCAGATTTCATCCAGCAGGGCATCAGGTGCAACTGTGTGTGCCCAGGAACGGTTGATACGCCATCTCTACAAGA
AAGAATACAAGCCAGAGGAAATCCTGAAGAGGCACAGAATGATTTCCTGAAGAGACAAAAGATGGGAAGATTTGCAACTG
CAGAAGAAATAGCCATGCTCTGCGTGTATGTGGTTTCCGATGAATCTGCTTATGTAACTGGTAACCCTGTCATCATTGAT
GGAGGATGGAGCTTGTGA

Alignment

ORF - retro_ggor_199 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 94.3 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  IGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHH
          IGQAAALAF.REGAKVIATDIN.SKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHH
Retrocopy IGQAAALAFVREGAKVIATDINVSKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHH

Parental  GTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGL
          .TVLDCE.KDWDFSMNLNV.S.YLMIKAFLPKMLAQKSGNII.MSSV.SS.KGVVNRCVYSTTKAAVIGL
Retrocopy ETVLDCEKKDWDFSMNLNVHSTYLMIKAFLPKMLAQKSGNIITMSSVVSSIKGVVNRCVYSTTKAAVIGL

Parental  TKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASD
          TKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEA.NDFLKRQK.GRFATAEEIAMLCVY..SD
Retrocopy TKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEAQNDFLKRQKMGRFATAEEIAMLCVYVVSD

Parental  ESAYVTGNPVIIDGGWSL
          ESAYVTGNPVIIDGGWSL
Retrocopy ESAYVTGNPVIIDGGWSL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.10 RPM	15.35 RPM
SRP007412_cerebellum	0.16 RPM	19.11 RPM
SRP007412_heart	0.09 RPM	4.38 RPM
SRP007412_kidney	0.86 RPM	91.92 RPM
SRP007412_liver	0.45 RPM	46.61 RPM
SRP007412_testis	0.00 RPM	10.26 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_199 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_199 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3499
Pongo abelii	retro_pabe_2891

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 5 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000164039	1 retrocopy	retro_hsap_3499,
Gorilla gorilla	ENSGGOG00000006381	1 retrocopy	retro_ggor_199 ,
Pongo abelii	ENSPPYG00000025868	1 retrocopy	retro_pabe_2891,
Xenopus tropicalis	ENSXETG00000021320	2 retrocopies	retro_xtro_35, retro_xtro_37,