RetrogeneDB ID: retro_ggor_2209

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 5:123042794..123043262(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: NTPCR
• Ensembl ID: ENSGGOG00000015198
• Aliases: None
• Description: None

Sequence

>retro_ggor_2209
GGATTTTATAGAGAGGAAGTCAGACAGGGAGGGAGAAGAATAGGATTTGATGTCATCATGTTGTCTGGCATCCAGGGGCC
TTTATTTAGAGTTGGGTTAGAGCCTCCACCTGGAAAATGTGGATGCCAAGTTGGGCATTATGTGGTTAACCTGACTTATT
TTGAGCAGTTGGCGCTCCCTATCTTGAGGAATGCAGATTCCAGCAGTGGCCCAGGGCAGAGAGTGTGCGTCACTGATGAG
AGTGGGAAAATGAAACTCTTTAGTTAGCCTTTCATCCAAGCTGTTTGTCAGATGCTATCTACCCCAGGGACTATAATCGC
TGGCACAATCCCAGTCCCTAAAGGAAAGTCACTGGCCCTTGTAGAAGAAATCAGAAACAGAAATGACGTGAAAGTGTTTA
ATGTCTCCAAGGAAGACAGAAACCACCTTCTGCCAGATATTATGATGTGTGTGCAGAGCAGCAGGAAG

Alignment

ORF - retro_ggor_2209 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.05 %
• Parental protein coverage: 82.11 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  GFYTEEVRQGGRRIGFDVVTLSGTRGPLSRVGLEPPPGKRECRVGQYVVDLTSFEQLALPVLRNADRSSG
          GFY.EEVRQGGRRIGFDV..LSG..GPL.RVGLEPPPGK..C.VG.YVV.LT.FEQLALP.LRNAD.SSG
Retrocopy GFYREEVRQGGRRIGFDVIMLSGIQGPLFRVGLEPPPGKCGCQVGHYVVNLTYFEQLALPILRNADSSSG

Parental  PGQRVCVIDEIGKMELFSQLFIQAVRQTLSTPGTIILGTIPVPKGKPLALVEEIRNRKDVKVFNVTKENR
          PGQRVCV.DE.GKM.LFS..FIQAV.Q.LSTPGTII.GTIPVPKGK.LALVEEIRNR.DVKVFNV.KE.R
Retrocopy PGQRVCVTDESGKMKLFS*PFIQAVCQMLSTPGTIIAGTIPVPKGKSLALVEEIRNRNDVKVFNVSKEDR

Parental  NHLLPDIVTCVQSSRK
          NHLLPDI..CVQSSRK
Retrocopy NHLLPDIMMCVQSSRK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	15.39 RPM
SRP007412_cerebellum	0.00 RPM	9.53 RPM
SRP007412_heart	0.00 RPM	6.19 RPM
SRP007412_kidney	0.00 RPM	14.15 RPM
SRP007412_liver	0.00 RPM	8.89 RPM
SRP007412_testis	0.00 RPM	21.55 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2209 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2209 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3246
Pan troglodytes	retro_ptro_2194
Pongo abelii	retro_pabe_2691

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Parental genes homology:

Parental genes homology involve 7 parental genes, and 7 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000018274	1 retrocopy	retro_cjac_1773,
Felis catus	ENSFCAG00000014211	1 retrocopy	retro_fcat_708,
Homo sapiens	ENSG00000135778	1 retrocopy	retro_hsap_3246,
Gorilla gorilla	ENSGGOG00000015198	1 retrocopy	retro_ggor_2209 ,
Macaca mulatta	ENSMMUG00000012614	1 retrocopy	retro_mmul_741,
Pongo abelii	ENSPPYG00000000108	1 retrocopy	retro_pabe_2691,
Pan troglodytes	ENSPTRG00000002116	1 retrocopy	retro_ptro_2194,