RetrogeneDB ID: retro_ggor_2613

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 7:96904936..96905548(-)
• Located in intron of: ENSGGOG00000015123

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SARNP
• Ensembl ID: ENSGGOG00000013217
• Aliases: None
• Description: None

Sequence

>retro_ggor_2613
ATGGTAACTGAGATGGTGGAGCTCCATAAGCTGAAGCTTGCTAAACTAAAGCAAGAATGTCTTGCTTGTGGTTTGGAGAC
CAAGGGAATAAAGCAAGATCTTATCCACAGACTCCAGGCGTATCTTGAAGAACATGCTGAAGAGGAGGCAAATGAAGATG
TACTAGGAGATGAAACAGAAGAAGAAACAAACCCCTTGTCAAATAGGAAGAACCCCCTGAAAAAAACTGTTGATGTGGCA
GCAGAGAAGAAAGTGGTGAAAATTACATCTGAAATACCACAGGCTGAGAGAATGCAGAAGAGGGCTGAACAATTCAGTGT
ACCTGTGAGCTTGGAGAGTAAGAAAGCTGCTCAGGCAGCTAGGTTTGGGATTTCTTCAGTTCCAACAAAAGTCTGTCATC
TGAACACACCTATGGTTAACTTGGATAAGCCGAAGGAAAGAGCTCAAAGATTTGGTTTGAATGTCTCTTCAATCTCCAGA
AAGTCTGAAGATGATGAGAAACTGAAAAAGAGGAAGGAGCGATTTGGGATTGTCACAAGTTCAGCTGGAACTGGAACCAC
AGAGGATACAGAGGCAAAGAAGAGGAAAAGAGCAGAGCGCTTTGGCATTGCC

Alignment

ORF - retro_ggor_2613 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.68 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MATETVELHKLKLAELKQECLARGLETKGIKQDLIHRLQAYLEEHAEEEANEEDVLGDETEEEET-KPIE
          M.TE.VELHKLKLA.LKQECLA.GLETKGIKQDLIHRLQAYLEEHAEEEANE.DVLGDETE.EET.KP..
Retrocopy MVTEMVELHKLKLAKLKQECLACGLETKGIKQDLIHRLQAYLEEHAEEEANE-DVLGDETE-EET<KPL-

Parental  LPVKEEEPPEK-TVDVAAEKKVVKITSEIPQTERMQKRAERFNVPVSLESKKAARAARFGISSVPTKGLS
          ..VK.EEPPEK.TVDVAAEKKVVKITSEIPQ.ERMQKRAE.F.VPVSLESKKAA.AARFGISSVPTK...
Retrocopy --VK*EEPPEK>TVDVAAEKKVVKITSEIPQAERMQKRAEQFSVPVSLESKKAAQAARFGISSVPTK-VC

Parental  SDNKPMVNLDKLKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTSSAGTGTTEDTEAKKRKRAERFG
          ..N.PMVNLDK.KERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTSSAGTGTTEDTEAKKRKRAERFG
Retrocopy HLNTPMVNLDKPKERAQRFGLNVSSISRKSEDDEKLKKRKERFGIVTSSAGTGTTEDTEAKKRKRAERFG

Parental  IA
          IA
Retrocopy IA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.96 RPM	23.88 RPM
SRP007412_cerebellum	0.87 RPM	23.17 RPM
SRP007412_heart	0.44 RPM	16.92 RPM
SRP007412_kidney	0.57 RPM	42.24 RPM
SRP007412_liver	0.18 RPM	20.50 RPM
SRP007412_testis	0.73 RPM	71.17 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2613 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2613 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3882
Pan troglodytes	retro_ptro_2644
Pongo abelii	retro_pabe_3116

---

Parental genes homology:

Parental genes homology involve 18 parental genes, and 32 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000011769	2 retrocopies	retro_amel_1602, retro_amel_347,
Bos taurus	ENSBTAG00000020662	1 retrocopy	retro_btau_202,
Callithrix jacchus	ENSCJAG00000007853	8 retrocopies	retro_cjac_1070, retro_cjac_1487, retro_cjac_1801, retro_cjac_2439, retro_cjac_2560, retro_cjac_389, retro_cjac_4139, retro_cjac_731,
Cavia porcellus	ENSCPOG00000011755	1 retrocopy	retro_cpor_1313,
Dipodomys ordii	ENSDORG00000001065	1 retrocopy	retro_dord_80,
Erinaceus europaeus	ENSEEUG00000015176	1 retrocopy	retro_eeur_549,
Homo sapiens	ENSG00000205323	1 retrocopy	retro_hsap_3882,
Gorilla gorilla	ENSGGOG00000013217	2 retrocopies	retro_ggor_2613 , retro_ggor_2753,
Loxodonta africana	ENSLAFG00000015053	1 retrocopy	retro_lafr_1024,
Microcebus murinus	ENSMICG00000010902	1 retrocopy	retro_mmur_358,
Monodelphis domestica	ENSMODG00000028949	1 retrocopy	retro_mdom_1909,
Mustela putorius furo	ENSMPUG00000000885	1 retrocopy	retro_mputfur_617,
Mus musculus	ENSMUSG00000078427	1 retrocopy	retro_mmus_54,
Nomascus leucogenys	ENSNLEG00000017599	2 retrocopies	retro_nleu_2779, retro_nleu_569,
Procavia capensis	ENSPCAG00000009477	2 retrocopies	retro_pcap_262, retro_pcap_45,
Pongo abelii	ENSPPYG00000004630	2 retrocopies	retro_pabe_3116, retro_pabe_3358,
Pan troglodytes	ENSPTRG00000029747	2 retrocopies	retro_ptro_2644, retro_ptro_2782,
Rattus norvegicus	ENSRNOG00000030520	2 retrocopies	retro_rnor_1326, retro_rnor_471,