RetrogeneDB ID: retro_ggor_757

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 11:122631932..122632841(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ENSG00000197849
• Ensembl ID: ENSGGOG00000023114
• Aliases: None
• Description: None

Sequence

>retro_ggor_757
ATGCCTGCCAAGAACTCCTCCTCCGTGACAGAGTTTATCCTCTCAGGCTTAACCGACCAGCCGGGACTCCAGATCCCCCT
CTTCTTCCTGTTTCTAGGTTTCTACGTGGTCACGGTAGTGGGGAACCTGGGCTTGATAACACTGATAGGGCTCAACTCTC
ACCTGCATATTCCCATGTACTTTTTCCTCTTCAACTTGTCCTTCATAGATTTTAGTTATTCCACTACCCTCGCCCCTAAA
ATGCTGATGAGCTTTGTCTCAAAGAAAAACATCATTTCCTATGCAGGGTGTATGACTCAGCTTTTTTTCTTCTGTTTCTT
TGTCTTTTCTGAATCCTATATTCTATCAGCGATGGCGTATGACCGCTACGTGGGCATCTGTAACCCACTGTTGTACACGG
TCACCATGTCTCCCCAGATGTGTTTGCTCCTTTTACTGGGTGTCTATGGGATGGGGATTTTGGGGCTGTGGCTCATATGG
GAAACATAATGTTTATGTCCTTTTGTGGAGACAACCTTGTCAATCACTATATGTGTGACATCCTTCCTCTCCTTGAGCTC
TCCCGCAACAGCTCTTACATAAATTTGCTGGTGGTTTTTATTATTGTGACCGTTGGCATTGGGGTGCCGATTGTCACCAT
TTTTCTGTCTTATGGTTTTATTCTTTCCAGCATTCTCCACATTAGTTCCACAGAGGGCAGGTCTAAAGCCTTCAGTACCT
GCAGTTCCCACATAATTGTGGTATCGCTTTTCTTTGGGTCAGGTGCTTTCATGTACCTCAAACCACCTTCTATTCTACCC
CTGGACCAGGGGAAAGTGTCCTCCATTTTTTTGTACTGCTGTGGTGCCCATGTTTAACCCATTAATCTACAGCCTGAAGA
ATAAAGATGTCAAAGTTGCCCTGAGGAGA

Alignment

ORF - retro_ggor_757 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 60.66 %
• Parental protein coverage: 97.43 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MSGENNSSVTEFILAGLSEQPELQLPLFLLFLGIYVVTVVGNLGMTTLIWLSSHLHTPMYYFLSSLSFID
          M...N.SSVTEFIL.GL..QP.LQ.PLF.LFLG.YVVTVVGNLG..TLI.L.SHLH.PMY.FL..LSFID
Retrocopy MPAKNSSSVTEFILSGLTDQPGLQIPLFFLFLGFYVVTVVGNLGLITLIGLNSHLHIPMYFFLFNLSFID

Parental  FCHSTVITPKMLVNFVTEKNIIFYPECMTQLYFFLIFAIAECHMLAAMAYDRYMAICSPLLYSVIISNKA
          F..ST...PKML..FV..KNII.Y..CMTQL.FF..F...E...L.AMAYDRY..IC.PLLY.V..S...
Retrocopy FSYSTTLAPKMLMSFVSKKNIISYAGCMTQLFFFCFFVFSESYILSAMAYDRYVGICNPLLYTVTMSPQM

Parental  CFSLILGVYIIGLV-CASVHTGCMFRVQFCKFDVINHYFCDLLPLLKLSCSSIYVNKLLILCVGAFNILV
          C..L.LGVY..G....A..H.G......FC.....NHY.CD.LPLL.LS..S.Y.N.L.........I.V
Retrocopy CLLLLLGVYGMGIL<GAVAHMGNIMFMSFCGDNLVNHYMCDILPLLELSRNSSYINLLVVFIIVTVGIGV

Parental  PSLTILCSYIFIIASILHIRSTEGRSKAFSTCSSHMLAVVIFFGSAAFMYLQPSSVSSMDQGKVSSVFY-
          P..TI..SY.FI..SILHI.STEGRSKAFSTCSSH...V..FFGS.AFMYL.P.S....DQGKVSS.F..
Retrocopy PIVTIFLSYGFILSSILHISSTEGRSKAFSTCSSHIIVVSLFFGSGAFMYLKPPSILPLDQGKVSSIFL>

Parental  TIVVPMLNPLIYSLRNKDVHVALKK
          T.VVPM.NPLIYSL.NKDV.VAL..
Retrocopy TAVVPMFNPLIYSLKNKDVKVALRR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	0.10 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_757 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_757 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 2 parental genes, and 10 retrocopies.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000023114	6 retrocopies	retro_ggor_682, retro_ggor_683, retro_ggor_684, retro_ggor_756, retro_ggor_757 , retro_ggor_758,
Macropus eugenii	ENSMEUG00000013370	4 retrocopies	retro_meug_2060, retro_meug_2076, retro_meug_35, retro_meug_447,