RetrogeneDB ID: retro_ggor_80

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:22093713..22094094(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000005438
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: PPP1R11
• Ensembl ID: ENSGGOG00000026830
• Aliases: None
• Description: None

Sequence

>retro_ggor_80
TCTCTTGAGGCAGGGGCTGGGCTGAGCGAGACCGTCACTGAGACAACGGTTACCGTGACAACCGAGCCCGAGAACCGGAG
CCTTACCATCAAACTTCCGAAACGGAAGCCAGAGAAAAAGGTGGAATGGACAAGTGACACTGTGGACAATGAACGCATGC
GCAGCCGCTCATCAAAATGCTGCTCTATTTATGAAAAATCCCGGGCCTTTGGCGAGAGCTCCACGGAAAGTGACGAGGAG
GAAGAAGAGGGCTGTGGTCATACACACTGTGTACGTGGCCACCGCAAAGGATGGCGTCCTGCAACCCTGGGACCGACCCC
CACCACCCCTCCCCCGCCTCCTGACCCTTCCCAGCCCCACGCAGGGCCAATGCAGCACTAA

Alignment

ORF - retro_ggor_80 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 91.13 %
• Parental protein coverage: 98.41 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  EAGAGLSETVTETTVTVTTEPENRSLTIKLRKRKPEKKVEWTSDTVDNEHMGRRSSKCCCIYEKPRAFGE
          EAGAGLSETVTETTVTVTTEPENRSLTIKL.KRKPEKKVEWTSDTVDNE.M..RSSKCC.IYEK.RAFGE
Retrocopy EAGAGLSETVTETTVTVTTEPENRSLTIKLPKRKPEKKVEWTSDTVDNERMRSRSSKCCSIYEKSRAFGE

Parental  SSTESDEEEEEGCGHTHCVRGHRKGRRRATLGPTPTTPPQPPDPSQPPPGPMQH
          SSTESDEEEEEGCGHTHCVRGHRKG.R.ATLGPTPTTPP.PPDPSQP..GPMQH
Retrocopy SSTESDEEEEEGCGHTHCVRGHRKGWRPATLGPTPTTPPPPPDPSQPHAGPMQH

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	50.83 RPM
SRP007412_cerebellum	0.00 RPM	26.00 RPM
SRP007412_heart	0.03 RPM	12.07 RPM
SRP007412_kidney	0.00 RPM	37.09 RPM
SRP007412_liver	0.03 RPM	25.22 RPM
SRP007412_testis	0.10 RPM	63.71 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_80 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_80 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 12 parental genes, and 13 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000020710	1 retrocopy	retro_cjac_2880,
Felis catus	ENSFCAG00000013592	1 retrocopy	retro_fcat_1794,
Gorilla gorilla	ENSGGOG00000026830	1 retrocopy	retro_ggor_80 ,
Macropus eugenii	ENSMEUG00000006493	2 retrocopies	retro_meug_715, retro_meug_933,
Macaca mulatta	ENSMMUG00000012122	1 retrocopy	retro_mmul_359,
Monodelphis domestica	ENSMODG00000016021	1 retrocopy	retro_mdom_98,
Nomascus leucogenys	ENSNLEG00000004933	1 retrocopy	retro_nleu_2257,
Otolemur garnettii	ENSOGAG00000001598	1 retrocopy	retro_ogar_1458,
Pongo abelii	ENSPPYG00000029642	1 retrocopy	retro_pabe_492,
Pan troglodytes	ENSPTRG00000017915	1 retrocopy	retro_ptro_2969,
Pteropus vampyrus	ENSPVAG00000008330	1 retrocopy	retro_pvam_894,
Ictidomys tridecemlineatus	ENSSTOG00000003632	1 retrocopy	retro_itri_159,