RetrogeneDB ID: retro_mmul_109

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 3:181563795..181564602(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMMUG00000013320
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: MMU.18991
• Ensembl ID: ENSMMUG00000000531
• Aliases: None
• Description: olfactory receptor 2A2 [Source:RefSeq peptide;Acc:NP_001180907]

Sequence

>retro_mmul_109
ATGATCTTGGGACTCATCTGTCTGGACCACAGTCTGCACACCCCCATGTACTTCTTCCTCTCACACCTGGCCGTCATTGA
CATGTCCTATGCTTCCAACAATGTTCCCAAGATGTTGGCAAATCTGATGAACAAGAAAAGAACCATCTCCTTTGTTCCAT
GCATAATGCAGACTTTTTTGTATTTCGCTTTTGCTGCTACAGAGTGTCTGATTTTGGTGGTGATGTCCTATGATAGGTAT
GTGGCCATCTGTCACCCTCTCCAGTACACTGTCATCATGAGCTGGAGAGTGTGCACAATCCTGGCTCTCATGTCCTGGTC
ATGTGGGTTTGCTCTGTCCTTGGTACATGCAATTCTCCTTCTAAGGTTGCCCTTCTGTGGGCCCTGGGATGTGAACCACC
TCTTCTGTGAAATTCTGTCTGTCCTCAAGCTGGCCTGTGCTGACACCTGGGTTAACCAAGTGGTCATATTTACTACCTGT
GTGTTTGTCTTAGTCGGGCCTCTTTGTTTGATGCTTGTCTCCTACATGCACATCATCGGGGCCATCCTGAAGATCCAGAC
AAAGGAGGGCCGCATAAAGGCCCTCTCCACCTGCTCCTCCCACCTGTGTGTGGTTGGACTCTTCTTTGGCATAGCCATGG
TGGTTTACATAGTCCCAGACTCTAATCAACGAGAGGAGCAGGAGAAAATGCTGTCCCTGTTTCACAGTCTCTTTAACCCA
ATGCTGAATCCCCTGATCTACAGCCTGAGGAACGCTCAGGTGAAGGGCGCCCTCCACAGAGCACTGCAGAGGACGCAGTC
TATGTAA

Alignment

ORF - retro_mmul_109 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.18 %
• Parental protein coverage: 86.45 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  IILGLICLDSRLHTPMYVFLSHLAIVDMSYASSTVPKMLANLVMHKKVISFAPCILQTFLYLAFAITECL
          .ILGLICLD..LHTPMY.FLSHLA..DMSYAS..VPKMLANL...K..ISF.PCI.QTFLY.AFA.TECL
Retrocopy MILGLICLDHSLHTPMYFFLSHLAVIDMSYASNNVPKMLANLMNKKRTISFVPCIMQTFLYFAFAATECL

Parental  ILVVMSYDRYVAICHPLQYTVIMSWRVCTILALTSWSCGFALSLVHAILLLRLPFCGPQDVNHLFCEILS
          ILVVMSYDRYVAICHPLQYTVIMSWRVCTILAL.SWSCGFALSLVHAILLLRLPFCGP.DVNHLFCEILS
Retrocopy ILVVMSYDRYVAICHPLQYTVIMSWRVCTILALMSWSCGFALSLVHAILLLRLPFCGPWDVNHLFCEILS

Parental  VLKLACADTWVNQVFIFATCVFVLVGPLSLILVSYTHIVGAILKIQTKEGRIKALSTCSSHLCVVGLFFG
          VLKLACADTWVNQV.IF.TCVFVLVGPL.L.LVSY.HI.GAILKIQTKEGRIKALSTCSSHLCVVGLFFG
Retrocopy VLKLACADTWVNQVVIFTTCVFVLVGPLCLMLVSYMHIIGAILKIQTKEGRIKALSTCSSHLCVVGLFFG

Parental  IAMVVYMVPDSNQREEQEKMLSLFHSLFNPMLNPLIYSLRNAQVKGALHRALQRKRPM
          IAMVVY.VPDSNQREEQEKMLSLFHSLFNPMLNPLIYSLRNAQVKGALHRALQR...M
Retrocopy IAMVVYIVPDSNQREEQEKMLSLFHSLFNPMLNPLIYSLRNAQVKGALHRALQRTQSM

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.11 RPM
SRP007412_brain_prefrontal_cortex	0.08 RPM	0.00 RPM
SRP007412_cerebellum	0.06 RPM	0.00 RPM
SRP007412_heart	0.47 RPM	0.06 RPM
SRP007412_kidney	0.23 RPM	0.12 RPM
SRP007412_liver	0.08 RPM	0.00 RPM
SRP007412_testis	0.04 RPM	0.00 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_109 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_109 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_109 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 1 parental gene, and 3 retrocopies.

Species	Parental gene accession	Retrocopies number
Macaca mulatta	ENSMMUG00000000531	3 retrocopies	retro_mmul_109 , retro_mmul_1652, retro_mmul_1738,