RetrogeneDB ID: retro_mmul_1652

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 3:181577755..181578683(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMMUG00000000532
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: MMU.18991
• Ensembl ID: ENSMMUG00000000531
• Aliases: None
• Description: olfactory receptor 2A2 [Source:RefSeq peptide;Acc:NP_001180907]

Sequence

>retro_mmul_1652
ATGGAGGACAACCAGTCACGGGTCACAGAATTCATCCTGGTTGGATTCCAGCTCAGTATGGAGATGGAAGTACTCCTCTT
CTGGATCTTCTCCCTGTTATATGTCTTCAGCCTGCTGGCAAATGGCATGATCTTTGGGCTCATCTGTGTGGATCCCAGAC
TACGCACCCCCATGTACTTCTTCCTCTCACACTTGGCCGTCATTGACATATCCTATGCTTCCAGCAATTTGCTCAACATG
CTGAAAAACCTAGTGCAACACAAAAAAAAAACTATCTCCTTCATCTCTTGCCATTAGGCAGATGGCTTTGTATTTGACTT
TTGCTGCTGCAGAGTGCCTGATTTTGGTGGTGATGTCCTATGATAGGTTTGTGACGATCTGCCATTCCCTGCATTACACT
ATCATGAACTGGAGAGTGTGCACAGTCCTGGCTGTTACTTCCTGGGCATGTGGATTTTCCCTGGCCCTCATAAATCTAAT
ACTCCTTCTAAGGCTGCCCTTCTGTGGACCCCAGGAGGTGAACCGCTTCTTCTGTGAAATTCTATCTGTCCTCAAACTGG
CCTGTGCAGATACCTGGATTAATGAAATTTTTGTCTTTGCTGGTCGTGTGTTTGTCTTAGTCAGGCCCCTTTCCTTGATG
CTGATCTCCTACATGCGCATCCTCTTGGCCATCCTGAAGATACAGTCAGAGGACCGCAGAAAAGCCTTTTCCACCTGCTC
CTCCCACCTCTGTGTGGTTGGGCTCTACTTTGGCATAGACATGGTGGTTTACCTGGTCCCAGATAACAGTCAACGACAGG
AGCAGGAGAAAATCCTCACTTTGTTTTACAGCCTTTTCAACCCATTGCTGAACCCCCTCATCTACAGCCTGCGGAACGCT
CAGGTGAAGGGTGCCTTATACAGAGCACTGCAGAAAAAGAGGACCATG

Alignment

ORF - retro_mmul_1652 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 68.27 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MESNRTWITEVVLLGFQVDPALELFLFGFFLLFYSFTLMGNGIILGLICLDSRLHTPMYVFLSHLAIVDM
          ME.N....TE..L.GFQ.....E..LF..F.L.Y.F.L..NG.I.GLIC.D.RL.TPMY.FLSHLA..D.
Retrocopy MEDNQSRVTEFILVGFQLSMEMEVLLFWIFSLLYVFSLLANGMIFGLICVDPRLRTPMYFFLSHLAVIDI

Parental  SYASSTVPKMLANLVMHKKV-ISFAPC-ILQTFLYLAFAITECLILVVMSYDRYVAICHPLQYTVIMSWR
          SYASS....ML.NLV.H....ISF..C.I.Q..LYL.FA..ECLILVVMSYDR.V.ICH.L.YT.IM.WR
Retrocopy SYASSNLLNMLKNLVQHXXXXISFISC>IRQMALYLTFAAAECLILVVMSYDRFVTICHSLHYT-IMNWR

Parental  VCTILALTSWSCGFALSLVHAILLLRLPFCGPQDVNHLFCEILSVLKLACADTWVNQVFIFATCVFVLVG
          VCT.LA.TSW.CGF.L.L...ILLLRLPFCGPQ.VN..FCEILSVLKLACADTW.N..F.FA..VFVLV.
Retrocopy VCTVLAVTSWACGFSLALINLILLLRLPFCGPQEVNRFFCEILSVLKLACADTWINEIFVFAGRVFVLVR

Parental  PLSLILVSYTHIVGAILKIQTKEGRIKALSTCSSHLCVVGLFFGIAMVVYMVPDSNQREEQEKMLSLFHS
          PLSL.L.SY..I..AILKIQ..E.R.KA.STCSSHLCVVGL.FGI.MVVY.VPD..QR.EQEK.L.LF.S
Retrocopy PLSLMLISYMRILLAILKIQS-EDRRKAFSTCSSHLCVVGLYFGIDMVVYLVPDNSQRQEQEKILTLFYS

Parental  LFNPMLNPLIYSLRNAQVKGALHRALQRKRPM
          LFNP.LNPLIYSLRNAQVKGAL.RALQ.KR.M
Retrocopy LFNPLLNPLIYSLRNAQVKGALYRALQKKRTM

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.11 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.06 RPM
SRP007412_kidney	0.23 RPM	0.12 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	0.00 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_1652 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_1652 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_1652 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 1 parental gene, and 3 retrocopies.

Species	Parental gene accession	Retrocopies number
Macaca mulatta	ENSMMUG00000000531	3 retrocopies	retro_mmul_109, retro_mmul_1652 , retro_mmul_1738,