RetrogeneDB ID: retro_mmul_2026

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 6:93867385..93868669(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MMU.4688
• Ensembl ID: ENSMMUG00000022767
• Aliases: None
• Description: elongation factor 2 [Source:RefSeq peptide;Acc:NP_001252725]

Sequence

>retro_mmul_2026
ATGGTGAACTTCATGGTAGAATAGATCCACGCCATCATGGACAAGAAGGCCAATATCCGCAACATGTCTGTCATCGCCCA
CGTGGTCCACGGCAAGTCCACACTGACAGACTCCCTGGTGTGCAAGGCGGGCATCATCGCCTCGGCCGGGGAGACACGCT
TCACTGACACCCGGAAGGATGAGCAGGAGCGTTGCATCACCATCAAGTCAACTGCCATCTCTCTCTTCTACGAGCTCTCG
GAGAATGACTTGAACTTCATCAAGCAAAGCAAGGACGGCGCCGGCTTCCTCATTAACCTCATCAACTCCCCCGGGCACGT
CGACTTCTCCTCGGAGGTGACGGCTGCCCTCCGAGTCACTGATGGTGCATTGGTTATGGTGGACTGCGTGTCAGGCGTGT
GTGTGCAGACGGAGACAGTGCTGCGGCAGGCCATTGCGGAGCGCATCGAGCCTGTGCTGATGATGAACAAGGTGGACCGT
GCCCTGCTGGAGCTGCAGCTGGAGCCCGAGGAGCTCTACCAGACCTTCCAGCGCATTGTGGAGAACGTGAACGTCATCAT
CTCCACCTACGGCGAGGGTGAGAGCGGCTCCATGGGCAACATCATGATCGATCCTGACCTCGGTACCGTGGGCTTCGGGT
CTGGCCTCCATGGGTGGGCCTTCACCCTGAAGCAGTTTGCGGAGATGTACGTGGCCAAGTTTGCTGCCAAAGGGGAGGGC
CAGTTGGGGCCTGCCGAGTGGGCCAAGAAAGTGGAGGACATGATAAAGAAGCTGTGGGGTGACAGGTACTTTGACCCAGC
CAATGGCAAGTTCAGCAAGTCAGCCACCAGCCCCGATGGGAAGAAGCTGCCACGCACCTTCTGCCAGTTGATCTTGGACC
CCATCTTCAAGGTGTTTGATGCCATCATGAATTTCAAGAAAGAGTAGACAGCAAAACTGATAGAGAAACTGGACATCAAA
CTGGACAGTGAGGACAAGGACAAAGAAGGCAAACCCCTGCTGAAGGCTGTGATGCGCCGCTGGCTGCCCGCCGGAGACGC
CTTGTTGCAGATGATCACCATCCATCTGCCCTCCCCTGTGACGGCCCAGAAGTACCACTGCGAGCTCCTGTAGGAGGGGC
CCCCGGACGACGAGGCTGCCATGGGCATTAAAAGCTGTGACCCCAAAGGCCCCCTTATGATGTATATTTCCAGAATGGTG
CCAACCTCCGACAAAGGTCGGTTCTACGCCTTTGGACGAGTCTTCTCGGGGCTGGTCTCCACCAGCCTGAAGGTCAGGAT
TATG

Alignment

ORF - retro_mmul_2026 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 95.35 %
• Parental protein coverage: 50.12 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITI
          MVNF.V..I.AIMDKKANIRNMSVIAHV.HGKSTLTDSLVCKAGIIASA..GETRFTDTRKDEQERCITI
Retrocopy MVNFMVE*IHAIMDKKANIRNMSVIAHVVHGKSTLTDSLVCKAGIIASA--GETRFTDTRKDEQERCITI

Parental  KSTAISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTE
          KSTAISLFYELSENDLNFIKQSKDGAGFLINLI.SPGHVDFSSEVTAALRVTDGALV.VDCVSGVCVQTE
Retrocopy KSTAISLFYELSENDLNFIKQSKDGAGFLINLINSPGHVDFSSEVTAALRVTDGALVMVDCVSGVCVQTE

Parental  TVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLG
          TVLRQAIAERI.PVLMMNK.DRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESG.MGNIMIDP.LG
Retrocopy TVLRQAIAERIEPVLMMNKVDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGSMGNIMIDPDLG

Parental  TVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSP
          TVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAE.AKKVEDM.KKLWGDRYFDPANGKFSKSATSP
Retrocopy TVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAEWAKKVEDMIKKLWGDRYFDPANGKFSKSATSP

Parental  DGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDAL
          DGKKLPRTFCQLILDPIFKVFDAIMNFKKE.TAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDAL
Retrocopy DGKKLPRTFCQLILDPIFKVFDAIMNFKKE*TAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDAL

Parental  LQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGL
          LQMITIHLPSPVTAQKY.CELL.EGPPDDEAAMGIKSCDPKGPLMMYIS.MVPTSDKGRFYAFGRVFSGL
Retrocopy LQMITIHLPSPVTAQKYHCELL*EGPPDDEAAMGIKSCDPKGPLMMYISRMVPTSDKGRFYAFGRVFSGL

Parental  VSTGLKVRIM
          VST.LKVRIM
Retrocopy VSTSLKVRIM

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	1.01 RPM	367.75 RPM
SRP007412_brain_prefrontal_cortex	1.35 RPM	1284.27 RPM
SRP007412_cerebellum	0.97 RPM	357.36 RPM
SRP007412_heart	7.24 RPM	760.86 RPM
SRP007412_kidney	2.00 RPM	523.82 RPM
SRP007412_liver	4.12 RPM	1133.13 RPM
SRP007412_testis	4.82 RPM	716.52 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_2026 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_2026 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_2026 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 6 parental genes, and 7 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000004258	2 retrocopies	retro_btau_1809, retro_btau_539,
Canis familiaris	ENSCAFG00000019158	1 retrocopy	retro_cfam_1503,
Latimeria chalumnae	ENSLACG00000011124	1 retrocopy	retro_lcha_83,
Macaca mulatta	ENSMMUG00000022767	1 retrocopy	retro_mmul_2026 ,
Monodelphis domestica	ENSMODG00000000750	1 retrocopy	retro_mdom_223,
Mus musculus	ENSMUSG00000034994	1 retrocopy	retro_mmus_2521,