RetrogeneDB ID: retro_mmul_2266

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 7:138606199..138606790(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: TMEM219
• Ensembl ID: ENSMMUG00000020273
• Aliases: None
• Description: transmembrane protein 219 [Source:RefSeq peptide;Acc:NP_001247771]

Sequence

>retro_mmul_2266
ATGGGCAACTGCCAGGCAGGGCACAACCTGCACCTGTGTCTGGCCCACCACCCACCTCTGGTCTGTGCCACTTTGATCCT
GCTGCTCCTTGGCCTCTCCGGCCTGGGCCTTGGCAGCTTCCTCCTCACCCACAGGACTGGCCTGCACAGCCCTGACCTCC
CCCAGGACTGGGTCTCTTTTTTGAGATCTTTTGGCCAGCTGACCCTGTGTCCCAGGAATGGGACAGTCACAGGGAAGTGG
CGAGGGTCTCACGTCATGAGCTTACTGACCACCTTGAACTTCGGAGACAGTCCAGACAGCAACAAGACCCAGACATTCCA
GGCCACAGTCCTGGGTAGTCAGAAGGGACTGAAAAGATCTTCTGCAGGACAACTGGTCCTTATCACAGCCAGGGTGACCA
CAGAAAGGACTGCAGGAACCTGCCCGTATTTTAGTGCTGTTCCAGGAATCCTACCCTCCAGCCAGCCACCCATATCCTGC
TCAGAGGAGGGCGCCGGAAATGCTACCCTGAGCCTTAGAATGGGTGAGGAGTGTGTTAGTGTCTGGAACCACGAAGGCCT
TGTGCTGACCAAGCTGCTCACCTCGGAGGAG

Alignment

ORF - retro_mmul_2266 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 93.91 %
• Parental protein coverage: 82.08 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MGNCQAGHNLHLCLAHHPPLVCATLILLLLGLSGLGLGSFLLTHRTGLRSPDIPQDWVSFLRSFGQLTLC
          MGNCQAGHNLHLCLAHHPPLVCATLILLLLGLSGLGLGSFLLTHRTGL.SPD.PQDWVSFLRSFGQLTLC
Retrocopy MGNCQAGHNLHLCLAHHPPLVCATLILLLLGLSGLGLGSFLLTHRTGLHSPDLPQDWVSFLRSFGQLTLC

Parental  PRNGTVTGKWRGSHVVGLLTTLNFGDSPDRNKTRIFQATVLGSQMGLKGSSAGQLVLITARVTTERTAGT
          PRNGTVTGKWRGSHV..LLTTLNFGDSPD.NKT..FQATVLGSQ.GLK.SSAGQLVLITARVTTERTAGT
Retrocopy PRNGTVTGKWRGSHVMSLLTTLNFGDSPDSNKTQTFQATVLGSQKGLKRSSAGQLVLITARVTTERTAGT

Parental  CLYFSAVPGILPSSQPPISCSEEGAGNATLSPRMGEECVSVWSHEGLVLTKLLTSEE
          C.YFSAVPGILPSSQPPISCSEEGAGNATLS.RMGEECVSVW.HEGLVLTKLLTSEE
Retrocopy CPYFSAVPGILPSSQPPISCSEEGAGNATLSLRMGEECVSVWNHEGLVLTKLLTSEE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	20.28 RPM
SRP007412_brain_prefrontal_cortex	0.16 RPM	41.09 RPM
SRP007412_cerebellum	0.00 RPM	18.15 RPM
SRP007412_heart	0.00 RPM	28.03 RPM
SRP007412_kidney	0.00 RPM	39.32 RPM
SRP007412_liver	0.00 RPM	55.58 RPM
SRP007412_testis	0.00 RPM	9.20 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_2266 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_2266 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_2266 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 4 parental genes, and 4 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000021785	1 retrocopy	retro_btau_1792,
Microcebus murinus	ENSMICG00000009088	1 retrocopy	retro_mmur_610,
Macaca mulatta	ENSMMUG00000020273	1 retrocopy	retro_mmul_2266 ,
Oryctolagus cuniculus	ENSOCUG00000006318	1 retrocopy	retro_ocun_517,