RetrogeneDB ID: retro_ptro_781

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 12:96629522..96629839(-)
• Located in intron of: ENSPTRG00000005323

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SNRPD1
• Ensembl ID: ENSPTRG00000009909
• Aliases: SNRPD1, SNRPD2
• Description: None

Sequence

>retro_ptro_781
ATGAAGCTCATGAGATTTTTGATGAAATGGTTCATGAAACTGTAACCTTGAATTGAAAAGTGGAACACAGGTCTATGGAA
CAGTCACAGGTGTGGATGTCACCGTGCTACACATCTTAAAGCATGAAAATGACCCTGAAGACAGAGAACCTGTACAGTTG
GAAACACAAATTTGAGGAAGTAACATTAGATATTTTACTCTACCAGACAGTTTACCTCTGGATACACTACTTGTGGATGT
TGAGCCTAAAGTAAAAACCTAAGAAAAGGGAAGCTGTTTGTTGCAGGAAGAGGCCAATGCAGAAGAAGAGGTAGAGG

Alignment

ORF - retro_ptro_781 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 71.05 %
• Parental protein coverage: 90.76 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 6

Retrocopy - Parental Gene Alignment:

Parental  MKLVRFLMK-LSHETVTI-ELKNGTQVHGTITGVDVSM-NTHLKA-VKMTLK-NREPVQLETLSIRGNNI
          MKL.RFLMK...HETVT..ELK.GTQV.GT.TGVDV....THLKA..KMTLK..REPVQLET..I.G.NI
Retrocopy MKLMRFLMK<MVHETVTL<ELKSGTQVYGTVTGVDVTV<ATHLKA<MKMTLK<DREPVQLET-QI*GSNI

Parental  RYFILPDSLPLDTLLVDVEPKVKS-KKREAVAGRGRGRGRGRGR
          RYF.LPDSLPLDTLLVDVEPKVK..KKREAV..R.R.....R.R
Retrocopy RYFTLPDSLPLDTLLVDVEPKVKT>KKREAVCCRKRPMQKKR*R

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.02 RPM	13.96 RPM
SRP007412_cerebellum	0.04 RPM	8.75 RPM
SRP007412_heart	0.06 RPM	5.13 RPM
SRP007412_kidney	0.00 RPM	8.08 RPM
SRP007412_liver	0.00 RPM	8.09 RPM
SRP007412_testis	0.00 RPM	10.33 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_781 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_781 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_781 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1147
Pongo abelii	retro_pabe_952
Macaca mulatta	retro_mmul_891

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Parental genes homology:

Parental genes homology involve 13 parental genes, and 24 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000006364	1 retrocopy	retro_acar_129,
Bos taurus	ENSBTAG00000008292	3 retrocopies	retro_btau_144, retro_btau_706, retro_btau_84,
Canis familiaris	ENSCAFG00000018247	1 retrocopy	retro_cfam_373,
Dasypus novemcinctus	ENSDNOG00000018773	4 retrocopies	retro_dnov_1254, retro_dnov_1716, retro_dnov_1832, retro_dnov_2403,
Felis catus	ENSFCAG00000012352	1 retrocopy	retro_fcat_1885,
Macaca mulatta	ENSMMUG00000003992	2 retrocopies	retro_mmul_887, retro_mmul_891,
Mustela putorius furo	ENSMPUG00000005567	1 retrocopy	retro_mputfur_185,
Oryctolagus cuniculus	ENSOCUG00000023761	1 retrocopy	retro_ocun_224,
Pongo abelii	ENSPPYG00000025874	3 retrocopies	retro_pabe_254, retro_pabe_948, retro_pabe_952,
Pan troglodytes	ENSPTRG00000009909	2 retrocopies	retro_ptro_291, retro_ptro_781 ,
Pteropus vampyrus	ENSPVAG00000005511	1 retrocopy	retro_pvam_450,
Rattus norvegicus	ENSRNOG00000013714	2 retrocopies	retro_rnor_2671, retro_rnor_2729,
Tursiops truncatus	ENSTTRG00000002654	2 retrocopies	retro_ttru_1566, retro_ttru_1890,