RetrogeneDB ID: retro_chof_13

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_91690:4876..5482(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSCHOG00000012678
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: RAB7A
• Ensembl ID: ENSCHOG00000000365
• Aliases: None
• Description: RAB7A, member RAS oncogene family [Source:HGNC Symbol;Acc:9788]

Sequence

>retro_chof_13
ATGAGTGGGAAATCCCTGCTCTTAAAGGTCATTCTCTTGGGTGATGGTGGAGTTGGGAAAAGCTCACTTATGAACCGTTA
TGTAACTAATAAGTTTGACTCCCAGGCTTTTCACACCATAGGGGTAGAGTTCTTAAACCGAGATCTGGAGGTAGATGGAC
ACTTTGTAACCCTTCAGATCTGGGACACTGCAGGGCAGGAACGTTTCAAGAGCCTTAGGACACCCTTCTACAGGGGAGCA
GACTGCTGCCTCTTGACCTTCAGCGTGGATGACCGACAGAGCTTTGAGAACCTTGGCAACTGGCAGAAAGAATTCATCTA
CTATGCAGATGTAAAGGACCCTGAGCACTTCCCTTTTGTAGTTCTGGGTAACAAGGTAGACAAAGAGGATAGGCAAGTGA
CTACCGAGGAGGCACGAGCCTGGTGCATGGAGAATGGGGATTACCCTTATCTAGAAACAAGTGCCAAAGATGATACTAAT
GTGACAGTGGCCTTTGAAGAAGCTGTCAGGCAGGTTTTGGCTGTAGAGGAACAGCTGGAGCATTGCATGTTAGGCCACAC
CATTGACTTGAATAGTGGCTCCAAAGCAGGATCTTCATGCTGTTAA

Alignment

ORF - retro_chof_13 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 56.4 %
• Parental protein coverage: 97.73 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  SRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQS
          S.K..LLKVI.LGD.GVGK.SLMN.YV..KF..Q...TIG..FL.....VD...VT.QIWDTAGQERF.S
Retrocopy SGKSLLLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGHFVTLQIWDTAGQERFKS

Parental  LGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAW
          L...FYRGADCC.L.F.V.....F..L..W..EF...A...DPE.FPFVVLGNK.D.E.RQV.T..A.AW
Retrocopy LRTPFYRGADCCLLTFSVDDRQSFENLGNWQKEFIYYADVKDPEHFPFVVLGNKVDKEDRQVTTEEARAW

Parental  CYSKNNIPYFETSAKEAINVEQAFQTIARNAL
          C......PY.ETSAK...NV..AF....R..L
Retrocopy CMENGDYPYLETSAKDDTNVTVAFEEAVRQVL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_13 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 10 parental genes, and 12 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000000365	1 retrocopy	retro_chof_13 ,
Felis catus	ENSFCAG00000022971	2 retrocopies	retro_fcat_661, retro_fcat_76,
Meleagris gallopavo	ENSMGAG00000007208	1 retrocopy	retro_mgal_7,
Myotis lucifugus	ENSMLUG00000008454	1 retrocopy	retro_mluc_1641,
Mustela putorius furo	ENSMPUG00000017333	1 retrocopy	retro_mputfur_1169,
Mus musculus	ENSMUSG00000079477	2 retrocopies	retro_mmus_3339, retro_mmus_3546,
Oryctolagus cuniculus	ENSOCUG00000001645	1 retrocopy	retro_ocun_259,
Pongo abelii	ENSPPYG00000013431	1 retrocopy	retro_pabe_90,
Rattus norvegicus	ENSRNOG00000012247	1 retrocopy	retro_rnor_2779,
Sarcophilus harrisii	ENSSHAG00000016787	1 retrocopy	retro_shar_65,