RetrogeneDB ID: retro_chof_2167

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_54972:853..1257(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: C1orf146
• Ensembl ID: ENSCHOG00000004012
• Aliases: None
• Description: chromosome 1 open reading frame 146 [Source:HGNC Symbol;Acc:24032]

Sequence

>retro_chof_2167
ATGGCTGAAAGTGGTGGAAAAGAAAAGTAAAATGGACAACCACAATTATTACTAGCTCATTGCTTAAGAGTCATGAAGCT
ACAACTGCCTAAGAAGATCAAAGTCACACATTTCAGTATTCAGATTCAGTGGAAAATGGATTAATGATATTTTCTTTTTC
TGGTATTGCATTTTTATTTATGAATGCCAAAGAATGCCTTATGTTAGCCGAAGAAATACTTTTAGCCAAAATTGAGACGT
TTATAAACATTCACCAAAATATTTTTTGGTTCTATCTGCTGCCCACCATGGACCTGATGAATGGAAGCTGATGTTCAGGA
TTCAGCAAGGATTCCTGGATAATAATTTACAGATACTTGCAGTACACAACACAGTCAATGCTATTAATCTTATTGTGCAC
TGTG

Alignment

ORF - retro_chof_2167 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.64 %
• Parental protein coverage: 74.59 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  MAESGGKEK-IKWTTTVIISSSLKSYEIATAFENRSHKVRYSDSVENGSIIFSLSGVAFLLMDAKECLMS
          MAESGGKEK..KWTTT.I.SS.LKS.E..TA.E..SH...YSDSVENG..IFS.SG.AFL.M.AKECLM.
Retrocopy MAESGGKEK<VKWTTTIITSSLLKSHEATTA*EDQSHTFQYSDSVENGLMIFSFSGIAFLFMNAKECLML

Parental  AEEIFLAKIEKFINIHQN-SFLVLSAALHGPEEWKLMFRIQQRFLGSNLRILPVHNTVNAIN-LMCTI
          AEEI.LAKIE.FINIHQN..FLVLSAA.HGP.EWKLMFRIQQ.FL..NL.IL.VHNTVNAIN.L.CT.
Retrocopy AEEILLAKIETFINIHQN<YFLVLSAAHHGPDEWKLMFRIQQGFLDNNLQILAVHNTVNAIN>LLCTV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2167 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 14 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000027936	1 retrocopy	retro_btau_490,
Choloepus hoffmanni	ENSCHOG00000004012	1 retrocopy	retro_chof_2167 ,
Callithrix jacchus	ENSCJAG00000017547	1 retrocopy	retro_cjac_1817,
Erinaceus europaeus	ENSEEUG00000003083	1 retrocopy	retro_eeur_601,
Homo sapiens	ENSG00000203910	1 retrocopy	retro_hsap_3381,
Gorilla gorilla	ENSGGOG00000006653	1 retrocopy	retro_ggor_2289,
Macropus eugenii	ENSMEUG00000013311	1 retrocopy	retro_meug_143,
Myotis lucifugus	ENSMLUG00000016984	1 retrocopy	retro_mluc_1260,
Macaca mulatta	ENSMMUG00000010094	1 retrocopy	retro_mmul_2107,
Nomascus leucogenys	ENSNLEG00000010426	1 retrocopy	retro_nleu_970,
Pongo abelii	ENSPPYG00000001156	1 retrocopy	retro_pabe_2780,
Pan troglodytes	ENSPTRG00000030530	1 retrocopy	retro_ptro_2298,
Ictidomys tridecemlineatus	ENSSTOG00000012506	1 retrocopy	retro_itri_404,
Tursiops truncatus	ENSTTRG00000014426	1 retrocopy	retro_ttru_1727,