RetrogeneDB ID: retro_chof_2524

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_8236:24270..24701(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MAD2L1
• Ensembl ID: ENSCHOG00000012813
• Aliases: None
• Description: MAD2 mitotic arrest deficient-like 1 (yeast) [Source:HGNC Symbol;Acc:6763]

Sequence

>retro_chof_2524
CTTGCTACTGATCCTGAGCTCATAAAATACCTAAACAATATGGTGGAGCAGCTGAAAGATTGTTTATGTAAGTGTTCAGT
TCAAAAACTAGTGGTAGTCATCTCAATTATTGAAAGTGGTGAAAGATGGCAATTTGATACTGAGTGTGACAAGACTGCAA
AAGATGAGAGTGCACCCAGAGAAAAGTCTCAGAAAACTATCCAAGATGAAACTCATTCAGTGATCTCACAGATCATAGCT
ACAGTAACATTTCTGCCACAATTGAAGTTTCTTGTTCGTTTGAGCTACTGATTTATACAGACAAAGATTTGGTTGTACCT
GAAAAATGGGAAGAGTCAGGACCACAGTTCATTGCCAGTTCTGAGGAAGTCCATCTTTGTTCATTTACTACTACAAGTCA
CAGAGTAAATAGCATGGTGGTCTACAAAATT

Alignment

ORF - retro_chof_2524 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 72.3 %
• Parental protein coverage: 71.57 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  VTTDPELIKYLNNVVEQLKXXXXXXXXXXXXXXXXXIESGEVLERWQFDIECDKTAKDESAPREKSQKAI
          ..TDPELIKYLNN.VEQLK.................IESG...ERWQFD.ECDKTAKDESAPREKSQK.I
Retrocopy LATDPELIKYLNNMVEQLKDCLCKCSVQKLVVVISIIESG---ERWQFDTECDKTAKDESAPREKSQKTI

Parental  QDEIRSVIRQITATVTFLPLL-EVS-SFDLLIYTDKDLVVPEKWEESGPQFITNSEEVRLRSFTTTIHKV
          QDE..SVI.QI.ATVTFLP.L.EVS.SF.LLIYTDKDLVVPEKWEESGPQFI..SEEV.L.SFTTT.H.V
Retrocopy QDETHSVISQIIATVTFLPQL<EVSCSFELLIYTDKDLVVPEKWEESGPQFIASSEEVHLCSFTTTSHRV

Parental  NSTVAYKI
          NS.V.YKI
Retrocopy NSMVVYKI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2524 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 38 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000012813	2 retrocopies	retro_chof_1340, retro_chof_2524 ,
Dasypus novemcinctus	ENSDNOG00000013456	1 retrocopy	retro_dnov_1348,
Erinaceus europaeus	ENSEEUG00000009629	1 retrocopy	retro_eeur_446,
Echinops telfairi	ENSETEG00000015756	1 retrocopy	retro_etel_724,
Homo sapiens	ENSG00000164109	2 retrocopies	retro_hsap_1350, retro_hsap_1707,
Gorilla gorilla	ENSGGOG00000002516	1 retrocopy	retro_ggor_1281,
Loxodonta africana	ENSLAFG00000029619	1 retrocopy	retro_lafr_1138,
Myotis lucifugus	ENSMLUG00000011092	8 retrocopies	retro_mluc_1242, retro_mluc_165, retro_mluc_1802, retro_mluc_1904, retro_mluc_1986, retro_mluc_2434, retro_mluc_609, retro_mluc_696,
Macaca mulatta	ENSMMUG00000004875	2 retrocopies	retro_mmul_1292, retro_mmul_1701,
Monodelphis domestica	ENSMODG00000018944	1 retrocopy	retro_mdom_633,
Mus musculus	ENSMUSG00000029910	2 retrocopies	retro_mmus_1684, retro_mmus_2573,
Nomascus leucogenys	ENSNLEG00000009092	1 retrocopy	retro_nleu_1832,
Oryctolagus cuniculus	ENSOCUG00000008243	4 retrocopies	retro_ocun_1424, retro_ocun_1469, retro_ocun_1486, retro_ocun_752,
Otolemur garnettii	ENSOGAG00000004054	1 retrocopy	retro_ogar_199,
Pongo abelii	ENSPPYG00000015029	2 retrocopies	retro_pabe_1121, retro_pabe_1403,
Pan troglodytes	ENSPTRG00000016401	2 retrocopies	retro_ptro_1156, retro_ptro_925,
Ictidomys tridecemlineatus	ENSSTOG00000025410	2 retrocopies	retro_itri_1592, retro_itri_327,
Tupaia belangeri	ENSTBEG00000011065	3 retrocopies	retro_tbel_4460, retro_tbel_4666, retro_tbel_664,
Tursiops truncatus	ENSTTRG00000011017	1 retrocopy	retro_ttru_1754,