RetrogeneDB ID: retro_cjac_1531

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 16:95900036..95900356(-)
• Located in intron of: ENSCJAG00000015597

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ATP5J
• Ensembl ID: ENSCJAG00000013803
• Aliases: None
• Description: ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 [Source:HGNC Symbol;Acc:847]

Sequence

>retro_cjac_1531
ATTCTTCAGAGGCTCTTCGGGTTCTCCTGTGTCTTTCGGTCAGCAGTCTCAGTCCATTTGCGGAAGAACATTGGTGTTAC
AGCAATGGTGTTTAATAAAGGACTTGATCTTTACAGAAACTCTTCATGAACAAGGTTAGACAACACAAATCTAAGTGACA
GACATCTGGAGGATTTGTTGATAATGACTCAGAGTACCAGCAAGAGCTGGAGAGGAAGCTTTTTAAGCTCAAGCAAGTGT
ATGGTAAAGCAGAGATGAATACATTCCCTAACTTCAAAGTTGAAGATCCCAAATTTGAAGTCATTGAAAAACCCCAGGCC

Alignment

ORF - retro_cjac_1531 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 67.59 %
• Parental protein coverage: 99.07 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  ILQRLFRFSSVIQSAVSVHLRRNIGVTAVAF-KELD-PIQKLFVDKIREYKSKRQTAGGPVDTGPEYQQD
          ILQRLF.FS.V..SAVSVHLR.NIGVTA..F.K.LD...QKLF..K.R..KSK.QT.GG.VD...EYQQ.
Retrocopy ILQRLFGFSCVFRSAVSVHLRKNIGVTAMVFNKGLD<SLQKLFMNKVRQHKSK*QTSGGFVDNDSEYQQE

Parental  LERELFKLKQMFGKGDMNTFPTFTFEDPKFEVFDKPPA
          LER.LFKLKQ..GK..MNTFP.F..EDPKFEV..KP.A
Retrocopy LERKLFKLKQVYGKAEMNTFPNFKVEDPKFEVIEKPQA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.18 RPM	12.07 RPM
SRP051959_heart	0.19 RPM	30.78 RPM
SRP051959_kidney	0.09 RPM	22.43 RPM
SRP051959_liver	0.19 RPM	27.18 RPM
SRP051959_lung	0.34 RPM	12.48 RPM
SRP051959_lymph_node	0.16 RPM	6.64 RPM
SRP051959_skeletal_muscle	0.13 RPM	33.63 RPM
SRP051959_spleen	0.13 RPM	9.52 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_1531 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_1531 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_1531 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3990
Pan troglodytes	retro_ptro_2708
Gorilla gorilla	retro_ggor_2678
Macaca mulatta	retro_mmul_2306

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 41 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000017167	1 retrocopy	retro_amel_1858,
Bos taurus	ENSBTAG00000000605	1 retrocopy	retro_btau_1653,
Canis familiaris	ENSCAFG00000024922	2 retrocopies	retro_cfam_1664, retro_cfam_1993,
Callithrix jacchus	ENSCJAG00000013803	3 retrocopies	retro_cjac_1531 , retro_cjac_2559, retro_cjac_665,
Equus caballus	ENSECAG00000017858	2 retrocopies	retro_ecab_548, retro_ecab_644,
Erinaceus europaeus	ENSEEUG00000011228	2 retrocopies	retro_eeur_693, retro_eeur_695,
Echinops telfairi	ENSETEG00000006438	4 retrocopies	retro_etel_1847, retro_etel_2218, retro_etel_468, retro_etel_832,
Felis catus	ENSFCAG00000029970	1 retrocopy	retro_fcat_1451,
Homo sapiens	ENSG00000154723	3 retrocopies	retro_hsap_2548, retro_hsap_3990, retro_hsap_4920,
Gorilla gorilla	ENSGGOG00000008265	2 retrocopies	retro_ggor_1593, retro_ggor_2678,
Myotis lucifugus	ENSMLUG00000015988	1 retrocopy	retro_mluc_1266,
Macaca mulatta	ENSMMUG00000008725	1 retrocopy	retro_mmul_2306,
Monodelphis domestica	ENSMODG00000021011	1 retrocopy	retro_mdom_1010,
Mustela putorius furo	ENSMPUG00000001001	2 retrocopies	retro_mputfur_1573, retro_mputfur_1582,
Nomascus leucogenys	ENSNLEG00000002412	1 retrocopy	retro_nleu_539,
Oryctolagus cuniculus	ENSOCUG00000006681	5 retrocopies	retro_ocun_1517, retro_ocun_1888, retro_ocun_326, retro_ocun_419, retro_ocun_789,
Pongo abelii	ENSPPYG00000011305	2 retrocopies	retro_pabe_1874, retro_pabe_1875,
Pan troglodytes	ENSPTRG00000013809	3 retrocopies	retro_ptro_1485, retro_ptro_2708, retro_ptro_3312,
Sorex araneus	ENSSARG00000000742	3 retrocopies	retro_sara_165, retro_sara_225, retro_sara_501,
Sus scrofa	ENSSSCG00000022586	1 retrocopy	retro_sscr_896,