RetrogeneDB ID: retro_cjac_2605

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 5:33000059..33000577(-)
• Located in intron of: ENSCJAG00000011495

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCJAG00000019334
• Aliases: None
• Description: None

Sequence

>retro_cjac_2605
ATGGAAGTTTCAGTGCACACGGACATGAGCCCTCTGAGGCCCCAGAACTATCTTTTTGGTTGTGAACTAAAGGCATGCAA
AGATAATCACTTTAAGGTGGACAATAATGAAAATGAGCAACAGTTATCTTTAAGAACGGTCAGTTTAGGGGCTGGTACAA
AGGTTGGATTACACATTGTCGAAGCAGAGGCAATGAGTTACAAAGGCAGTCCAATTAAAGTAACACTGGCAACTTTGAAA
ATGTCTGTACAGCCAATGGTTTCCCTTGGGGGCTTTGAAATAACACCACCCATGCTCTTACAGTTGAAGTGTGGTTCCGG
GCCAGTGCATATTAGTGGACAGCATTCAGTAGCTGTGGAGTAAGATGCAGAGTCAGAAGATGAAGAGGAGGAGGATGTGA
AACTCTTAAATATATCTGGAAGGCGATCTGCCCCGGACGTGGTAGCAAGGCTCCACAGAAAAAAGTAAAACTTGCTGAAG
ATGATGATGACGATGAGGATTATTTTGATGATGAGGAA

Alignment

ORF - retro_cjac_2605 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 81.61 %
• Parental protein coverage: 58.45 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGS
          ME.S...DMSPLRPQNYLFGCELKA.KD.HFKVDN.ENE.QLSLRTVSLGAG.K..LHIVEAEAM.Y.GS
Retrocopy MEVSVHTDMSPLRPQNYLFGCELKACKDNHFKVDNNENEQQLSLRTVSLGAGTKVGLHIVEAEAMSYKGS

Parental  PIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSMSG
          PIKVTLATLKMSVQP.VSLGGFEITPP..L.LKCGSGPVHISGQH.VAVE.DAESEDEEEEDVKLL..SG
Retrocopy PIKVTLATLKMSVQPMVSLGGFEITPPMLLQLKCGSGPVHISGQHSVAVE*DAESEDEEEEDVKLLNISG

Parental  KRSA-PGGGSKVPQKKVKLAADEDDDDDEDDDDD
          .RSA.PG.GSK.PQKKVKLA.D.DDD.D..DD..
Retrocopy RRSA<PGRGSKAPQKKVKLAEDDDDDEDYFDDEE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.44 RPM	103.02 RPM
SRP051959_heart	0.28 RPM	88.32 RPM
SRP051959_kidney	0.51 RPM	119.21 RPM
SRP051959_liver	0.24 RPM	110.79 RPM
SRP051959_lung	0.44 RPM	107.02 RPM
SRP051959_lymph_node	0.27 RPM	125.98 RPM
SRP051959_skeletal_muscle	0.13 RPM	89.78 RPM
SRP051959_spleen	0.34 RPM	120.13 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_2605 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_2605 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_2605 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2478
Gorilla gorilla	retro_ggor_1543

---

Parental genes homology:

Parental genes homology involve 15 parental genes, and 99 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000003910	1 retrocopy	retro_amel_983,
Bos taurus	ENSBTAG00000015316	2 retrocopies	retro_btau_538, retro_btau_56,
Canis familiaris	ENSCAFG00000016912	3 retrocopies	retro_cfam_22, retro_cfam_286, retro_cfam_900,
Callithrix jacchus	ENSCJAG00000017650	2 retrocopies	retro_cjac_2491, retro_cjac_3052,
Callithrix jacchus	ENSCJAG00000019334	13 retrocopies	retro_cjac_1559, retro_cjac_1682, retro_cjac_1696, retro_cjac_1733, retro_cjac_2075, retro_cjac_2351, retro_cjac_2368, retro_cjac_2533, retro_cjac_2605 , retro_cjac_3270, retro_cjac_3416, retro_cjac_4117, retro_cjac_838,
Equus caballus	ENSECAG00000021950	4 retrocopies	retro_ecab_1016, retro_ecab_1100, retro_ecab_393, retro_ecab_544,
Felis catus	ENSFCAG00000030268	3 retrocopies	retro_fcat_156, retro_fcat_376, retro_fcat_720,
Homo sapiens	ENSG00000181163	30 retrocopies	retro_hsap_1275, retro_hsap_129, retro_hsap_1526, retro_hsap_1580, retro_hsap_1593, retro_hsap_1621, retro_hsap_2226, retro_hsap_2375, retro_hsap_2478, retro_hsap_2856, retro_hsap_2862, retro_hsap_3355, retro_hsap_3460, retro_hsap_3609, retro_hsap_3636, retro_hsap_3718, retro_hsap_3776, retro_hsap_3808, retro_hsap_3817, retro_hsap_3822, retro_hsap_3962, retro_hsap_4666, retro_hsap_4753, retro_hsap_4785, retro_hsap_614, retro_hsap_638, retro_hsap_690, retro_hsap_717, retro_hsap_785, retro_hsap_961,
Gorilla gorilla	ENSGGOG00000007220	12 retrocopies	retro_ggor_1543, retro_ggor_1660, retro_ggor_1976, retro_ggor_2453, retro_ggor_2454, retro_ggor_2539, retro_ggor_2559, retro_ggor_2571, retro_ggor_2681, retro_ggor_2959, retro_ggor_560, retro_ggor_591,
Macaca mulatta	ENSMMUG00000015781	1 retrocopy	retro_mmul_203,
Mus musculus	ENSMUSG00000057113	5 retrocopies	retro_mmus_1301, retro_mmus_1798, retro_mmus_3131, retro_mmus_539, retro_mmus_550,
Oryctolagus cuniculus	ENSOCUG00000011117	1 retrocopy	retro_ocun_412,
Otolemur garnettii	ENSOGAG00000013616	14 retrocopies	retro_ogar_1554, retro_ogar_1623, retro_ogar_1671, retro_ogar_1776, retro_ogar_2015, retro_ogar_2168, retro_ogar_2207, retro_ogar_2461, retro_ogar_2605, retro_ogar_2832, retro_ogar_3037, retro_ogar_536, retro_ogar_595, retro_ogar_614,
Pongo abelii	ENSPPYG00000016037	7 retrocopies	retro_pabe_2405, retro_pabe_3072, retro_pabe_3261, retro_pabe_3627, retro_pabe_3699, retro_pabe_486, retro_pabe_532,
Pteropus vampyrus	ENSPVAG00000002211	1 retrocopy	retro_pvam_851,