RetrogeneDB ID: retro_ecab_734

Retrocopy location

• Organism: Horse (Equus caballus)
• Coordinates: 3:107566486..107566926(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: HPRT1
• Ensembl ID: ENSECAG00000017534
• Aliases: None
• Description: hypoxanthine phosphoribosyltransferase 1 [Source:HGNC Symbol;Acc:5157]

Sequence

>retro_ecab_734
AAATTCTCTGCTGACTTGCTGGATTACACCAAAGCCCTGAACAGAAATAGTGATATATCCATCCCATGACTGCAGATTTT
ATCAGACTGAAGAGCTACCTTAATGACCATTCAATTGGGACCATAAACGTAATTTATGGAGATGATTTTGCAACTTTAAC
TGGAAAGAATGTCTTGATTACTAAAGATATAATTGACATCAGCAAAATAATGCAAATCTTGCTTTCCTTAGTCAAGCAGT
ATAATCCAAAGATGGTCAGCATTGGAAGTTTGCTGTGAAAGAGATCCCCCCACTGAACTATTGGATGTAGGACAGATTGT
GTTGGATTTGAAATTCCAGACCAATTTGTTATAGGATGTGCCCTTGACTATAACTAATACATCAAGGATATCACTCATGT
TTGTCTCATTAGCAAAACTGGAAAAGCAAAATACAAAGCC

Alignment

ORF - retro_ecab_734 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 67.57 %
• Parental protein coverage: 69.52 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  KFFADLLDYIKVLNRNSDRSIP-MTVDFIRLKSYCNDQSTGDIKVIGGDDLSTLTGKVCIFPQDIIDTGK
          KF.ADLLDY.K.LNRNSD.SIP.MT.DFIRLKSY.ND.S.G.I.VI.GDD..TLTGK......DIID..K
Retrocopy KFSADLLDYTKALNRNSDISIP<MTADFIRLKSYLNDHSIGTINVIYGDDFATLTGKNVLITKDIIDISK

Parental  TMQTLLSLVKEYNPKMVKVASLLVKRTPR-SVGYRPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISE
          .MQ.LLSLVK.YNPKMV...SLL.KR.P....G.R.D.VGFEIPD.FV.G.ALDYN.Y..D..HVC.IS.
Retrocopy IMQILLSLVKQYNPKMVSIGSLL*KRSPH*TIGCRTDCVGFEIPDQFVIGCALDYN*YIKDITHVCLISK

Parental  TGKEKYKA
          TGK.KYKA
Retrocopy TGKAKYKA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP021940_articular_cartilage	0.00 RPM	2.72 RPM
SRP021940_cerebellum	0.00 RPM	15.53 RPM
SRP021940_embryo	0.03 RPM	5.29 RPM
SRP021940_placental_villous	0.00 RPM	11.88 RPM
SRP021940_synovial_membrane	0.00 RPM	5.85 RPM
SRP021940_testis	0.00 RPM	5.05 RPM

ChIP-Seq

Equus caballus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ecab_734 retrocopy.

TSS

Equus caballus was not studied using FANTOM5 data.

Lab

retro_ecab_734 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ecab_734 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 21 parental genes, and 40 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000001339	1 retrocopy	retro_amel_129,
Bos taurus	ENSBTAG00000014685	3 retrocopies	retro_btau_162, retro_btau_179, retro_btau_721,
Cavia porcellus	ENSCPOG00000002512	1 retrocopy	retro_cpor_1299,
Dasypus novemcinctus	ENSDNOG00000008495	5 retrocopies	retro_dnov_1480, retro_dnov_1908, retro_dnov_2057, retro_dnov_255, retro_dnov_763,
Equus caballus	ENSECAG00000017534	1 retrocopy	retro_ecab_734 ,
Felis catus	ENSFCAG00000004575	2 retrocopies	retro_fcat_104, retro_fcat_1608,
Homo sapiens	ENSG00000165704	1 retrocopy	retro_hsap_917,
Gorilla gorilla	ENSGGOG00000008050	1 retrocopy	retro_ggor_740,
Loxodonta africana	ENSLAFG00000009892	2 retrocopies	retro_lafr_1042, retro_lafr_475,
Microcebus murinus	ENSMICG00000006547	1 retrocopy	retro_mmur_1186,
Myotis lucifugus	ENSMLUG00000003591	1 retrocopy	retro_mluc_2107,
Macaca mulatta	ENSMMUG00000008303	1 retrocopy	retro_mmul_1118,
Oryctolagus cuniculus	ENSOCUG00000003186	1 retrocopy	retro_ocun_1082,
Otolemur garnettii	ENSOGAG00000003881	3 retrocopies	retro_ogar_1886, retro_ogar_3298, retro_ogar_3463,
Pongo abelii	ENSPPYG00000020733	2 retrocopies	retro_pabe_3601, retro_pabe_791,
Pan troglodytes	ENSPTRG00000022287	2 retrocopies	retro_ptro_2042, retro_ptro_636,
Rattus norvegicus	ENSRNOG00000031367	2 retrocopies	retro_rnor_1208, retro_rnor_2491,
Sarcophilus harrisii	ENSSHAG00000007965	3 retrocopies	retro_shar_470, retro_shar_513, retro_shar_661,
Tupaia belangeri	ENSTBEG00000000859	5 retrocopies	retro_tbel_1607, retro_tbel_2234, retro_tbel_3627, retro_tbel_4320, retro_tbel_729,
Tarsius syrichta	ENSTSYG00000009579	1 retrocopy	retro_tsyr_2050,
Vicugna pacos	ENSVPAG00000009133	1 retrocopy	retro_vpac_122,