RetrogeneDB ID: retro_ggor_1422

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 19:7951812..7952545(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000025707
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: ZRSR2
• Ensembl ID: ENSGGOG00000011962
• Aliases: None
• Description: None

Sequence

>retro_ggor_1422
ATGGCTGCGCCCGAGAAGGTGACATTTCCAGAGAAACCAAGCCACAAAAAGTACAGGGCCGCCCTGAAGAAGGAGAAACG
AAAGAAACGCCAGCAGGAACTTGCTCCACTGAGGGACTCAGGACTCTCACAGAAAGAGGAGGACACTTTTATTGAAAAAC
AACAACTAGAAAAGCTATGGGGAAGAGAGAGGCAAAGATTACATGAGGAGTGGTTGCTGAGAGAGCAGAAGGCACAAGAA
GAATTCAGAATAAAGAAGGAAAAGGAAGAGGTGGCTAGAAAACGGCAAGAACAAGAGCGAATGTTAAAGGAACAATGGGA
AGAACAGCAGAGGAAAGAGAGAGGGGAGGAGGAACAGAAACGACAGAAGAAACAAAAACCGGAAGCTGTCCAGAAGATGC
TGGATCAGGCTGAAAATGAGTTGGAAAATGGCGCCACATGGCAAAACCCGGAACCCCCCCTTGGATTTCAGAGTCATGGA
GAAGGATGGAGTTAATTGTCCCTTCTACAGTAAAACAGGAGCTTGCAGATTTGGAGACAGATGTTCACATAATTTCCCAA
CGTCCAGTCCTACCCTTCTTATTAAAAGCATGTTTACAGTGTTTGGAATGGAGCAGTGCAGGAGGGATGACTATGACTCC
GAAGCAAGCTTGGAGTACAGCGAGGAAGAAACCTACCAACAATTCCTAGATTTCTATGAGGATGTGCTGCCCGAGTTCAA
GAACGTGGGGAGA

Alignment

ORF - retro_ggor_1422 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 76.47 %
• Parental protein coverage: 56.82 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSAPPPKEEEEDTFIEEQQLEEEKLLERERQR
          MAAPEK.TFPEKPSHKKYRAALKKEKRKKR.QELA.LRDS....KEE..DTFIE.QQLE..KL..RERQR
Retrocopy MAAPEKVTFPEKPSHKKYRAALKKEKRKKRQQELAPLRDSGLSQKEE--DTFIEKQQLE--KLWGRERQR

Parental  LHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERFFPDEEICETLRRNEGNEIDSKLMKKNQQYVTTNK
          LHEEWLLREQKAQEEFRIKKEKEE.A.KRQE.QER........E...R.E..E...K..KK.Q......K
Retrocopy LHEEWLLREQKAQEEFRIKKEKEEVARKRQE-QERMLKEQ--WEEQQRKERGEEEQKRQKK-QKPEAVQK

Parental  QLD----QLENGTTWQNPEPPV-DFRVMEKDRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFT
          .LD.....LENG.TWQNPEPP..DFRVMEKD..NCPFYSKTGACRFGDRCS..HNFPTSSPTLLIKSMFT
Retrocopy MLDQAENELENGATWQNPEPPL>DFRVMEKDGVNCPFYSKTGACRFGDRCS--HNFPTSSPTLLIKSMFT

Parental  TFGMEQCRRDDYDPDASLEYSEEETYQQFLDFYEDVLPEFKNVGK
          .FGMEQCRRDDYD..ASLEYSEEETYQQFLDFYEDVLPEFKNVG.
Retrocopy VFGMEQCRRDDYDSEASLEYSEEETYQQFLDFYEDVLPEFKNVGR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	1.20 RPM	15.97 RPM
SRP007412_cerebellum	1.26 RPM	23.48 RPM
SRP007412_heart	1.13 RPM	8.26 RPM
SRP007412_kidney	2.17 RPM	17.21 RPM
SRP007412_liver	0.76 RPM	8.44 RPM
SRP007412_testis	1.35 RPM	10.67 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1422 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1422 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 10 parental genes, and 10 retrocopies.

Species	Parental gene accession	Retrocopies number
Felis catus	ENSFCAG00000009333	1 retrocopy	retro_fcat_44,
Homo sapiens	ENSG00000169249	1 retrocopy	retro_hsap_39,
Gorilla gorilla	ENSGGOG00000011962	1 retrocopy	retro_ggor_1422 ,
Gorilla gorilla	ENSGGOG00000016828	1 retrocopy	retro_ggor_150,
Macaca mulatta	ENSMMUG00000014054	1 retrocopy	retro_mmul_2030,
Mus musculus	ENSMUSG00000031370	1 retrocopy	retro_mmus_233,
Nomascus leucogenys	ENSNLEG00000009496	1 retrocopy	retro_nleu_1,
Pan troglodytes	ENSPTRG00000021693	1 retrocopy	retro_ptro_25,
Rattus norvegicus	ENSRNOG00000033176	1 retrocopy	retro_rnor_176,
Tarsius syrichta	ENSTSYG00000005278	1 retrocopy	retro_tsyr_1826,