RetrogeneDB ID: retro_ggor_508

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 10:55521777..55522279(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: C12ORF49
• Ensembl ID: ENSGGOG00000015690
• Aliases: None
• Description: None

Sequence

>retro_ggor_508
GAAGAGGAGGAGAGGGCAGTGAGAGATAGGAATCTCCTCCAGGTTCAAGACCACGATCAGCCCATCCCTTGGAAAGTGCA
GTTTAACCTGGGCAATAGCAGTCGCCTGAGCAGCCAATGCCTCAACTCCATTCAAAGGAAGCACGTCCTCACGGGTGAAC
TAGGCTGCGTTTGGGAGAGAAAGTATTTGCAGGCGCATGGCTGCGGTCAAGTCAACGTCCCTAGCATAAAGCAACACTGC
CGCAAAGGCTGCTGGCCCGACGGCTGCTGCAGCGCCTCCTCGACTGCGTCTCCCGCTGCCTGCAGCCCAGACGCAGCTTC
TCCCGGAGCGCTTCTAACCGCGCAGCGGTGGCGTTCCAGAGACTCTTCATGGCCCTTGCTCTCGAGGACCCCTTGGAGTG
GTGCCTGGCCGAATGCAGGGCCTCATTCCAGAGCTTGCAGCATGAGAACACCTACCGGGACCCCTAGCAAAGTACTGCCG
TGGAGTCAGCCCCGGAGCTCTT

Alignment

ORF - retro_ggor_508 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 63.74 %
• Parental protein coverage: 81.46 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  KQEERAVRDRNLLQVHDHNQPIPWKVQFNLGNSSRPSNQCRNSIQGKHLITDELGYVCERKDLLVNGCCN
          ..EERAVRDRNLLQV.DH.QPIPWKVQFNLGNSSR.S.QC.NSIQ.KH..T.ELG.V.ERK.L...GC..
Retrocopy EEEERAVRDRNLLQVQDHDQPIPWKVQFNLGNSSRLSSQCLNSIQRKHVLTGELGCVWERKYLQAHGCGQ

Parental  VNVPSTKQYCCDGCWPNGCCSAYEY-CVSCCLQPNKQLLLERFLNRAAVAFQNLFMAVG--DTFSLILRN
          VNVPS.KQ.C..GCWP.GCCSA....CVS.CLQP..........NRAAVAFQ.LFMA....D.....L..
Retrocopy VNVPSIKQHCRKGCWPDGCCSASST<CVSRCLQPRRSFSRSAS-NRAAVAFQRLFMALALEDPLEWCLAE

Parental  ARKGQQSVQHENTYRDP-IAKYCYGESPPEL
          .R...QS.QHENTYRDP..AKYC.G.SP..L
Retrocopy CRASFQSLQHENTYRDP<LAKYCRGVSPGAL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	11.56 RPM
SRP007412_cerebellum	0.00 RPM	5.40 RPM
SRP007412_heart	0.00 RPM	2.38 RPM
SRP007412_kidney	0.00 RPM	6.26 RPM
SRP007412_liver	0.00 RPM	2.80 RPM
SRP007412_testis	0.00 RPM	13.88 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_508 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_508 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 10 parental genes, and 23 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000012481	2 retrocopies	retro_amel_1518, retro_amel_1578,
Bos taurus	ENSBTAG00000047139	1 retrocopy	retro_btau_1667,
Callithrix jacchus	ENSCJAG00000009570	1 retrocopy	retro_cjac_1471,
Dasypus novemcinctus	ENSDNOG00000001294	9 retrocopies	retro_dnov_126, retro_dnov_1532, retro_dnov_1609, retro_dnov_1622, retro_dnov_1739, retro_dnov_2042, retro_dnov_2185, retro_dnov_2285, retro_dnov_232,
Echinops telfairi	ENSETEG00000016892	3 retrocopies	retro_etel_1064, retro_etel_1377, retro_etel_410,
Homo sapiens	ENSG00000111412	1 retrocopy	retro_hsap_4758,
Gorilla gorilla	ENSGGOG00000015690	2 retrocopies	retro_ggor_2963, retro_ggor_508 ,
Myotis lucifugus	ENSMLUG00000011912	1 retrocopy	retro_mluc_166,
Macaca mulatta	ENSMMUG00000018247	2 retrocopies	retro_mmul_2376, retro_mmul_2537,
Pan troglodytes	ENSPTRG00000005500	1 retrocopy	retro_ptro_2798,