RetrogeneDB ID: retro_ggor_79

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 12:77462600..77463221(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000002908
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: RALB
• Ensembl ID: ENSGGOG00000001648
• Aliases: None
• Description: None

Sequence

>retro_ggor_79
ATGGCCGCAAATAAGCCCAAGGGTCAGAATAATTTGGCCTTACACAAAGTCATCACGGTGGGCAGTACCGGTGTGGGCAA
GGCAGCTCTGACTCTACAGTTCATGTACGATGAGTTTGTGGAGGACTATGAGCTTATCAAAGAAGGCACCTATCGGAAGA
GAGTAGTACTGGTTGGCGAGGAAGTACAGATCGGTGTCTTAGAAACAGCTGGGCAGGAGGACTATGCTGCAATTAGGGAC
AACTATTTCCGAAGCAGAGAGGGGTTTCTCTGTGTCTTCTCTATTGCAGAAATGGAATCCTTTGCAGCTACAGCTGACTT
CAGGGAGCAGATTTTAAGAGTAAAAGAAGATGAGAATGTTCCATTTCTACTGGTTGGTAACAAATCAGATTTAGAAGATA
AAAGGCCGGTTTCTGTAAAAGAGGCAAAAAACAGAGCTGACCAGTGGACTGTTAACTATGTGGAAACATCTGCTAAAACA
CGAGCTAATGTTGACAAGGTATTTTTTTATTTAATGAGAGAAATTCGAGCAAAAAAGATGGAAGACAGCAAAGAAAAGAA
TGGAAAAAAGAAGAGGAAAAGTTCAGCCAAGAGAATCAGAGAAAGATGCTGCATTTTATAA

Alignment

ORF - retro_ggor_79 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 72.95 %
• Parental protein coverage: 92.79 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAANKSKGQSSLALHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTA
          MAANK.KGQ..LALHKVI.VGS.GVGK.ALTLQFMYDEFVEDYE..K...YRK.VVL.GEEVQI..L.TA
Retrocopy MAANKPKGQNNLALHKVITVGSTGVGKAALTLQFMYDEFVEDYELIKEGTYRKRVVLVGEEVQIGVLETA

Parental  GQEDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDLEERRQVPV
          GQEDYAAIRDNYFRS.EGFL.VFSI.E.ESF.ATA.FREQILRVK.E....P.L.VGNKSDLE..R.V.V
Retrocopy GQEDYAAIRDNYFRSREGFLCVFSIAEMESFAATADFREQILRVK-EDENVPFLLVGNKSDLEDKRPVSV

Parental  EEARSKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKDKNGKKSSKNK-KSFKERCCLL
          .EA...A..W.V.YVETSAKTRANVDKVFF.LMREIR.KKM...K.KNGKK..K...K...ERCC.L
Retrocopy KEAKNRADQWTVNYVETSAKTRANVDKVFFYLMREIRAKKMEDSKEKNGKKKRKSSAKRIRERCCIL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	1.97 RPM	56.63 RPM
SRP007412_cerebellum	1.77 RPM	16.74 RPM
SRP007412_heart	0.66 RPM	21.17 RPM
SRP007412_kidney	2.54 RPM	73.44 RPM
SRP007412_liver	1.40 RPM	26.51 RPM
SRP007412_testis	7.67 RPM	26.73 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_79 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_79 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 3 parental genes, and 3 retrocopies.

Species	Parental gene accession	Retrocopies number
Gorilla gorilla	ENSGGOG00000001648	1 retrocopy	retro_ggor_79 ,
Gorilla gorilla	ENSGGOG00000025649	1 retrocopy	retro_ggor_2836,
Sarcophilus harrisii	ENSSHAG00000012747	1 retrocopy	retro_shar_648,