RetrogeneDB ID: retro_nleu_2197

Retrocopy location

• Organism: Gibbon (Nomascus leucogenys)
• Coordinates: GL397333.1:11099950..11100601(-)
• Located in intron of: ENSNLEG00000002859

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: CHMP5
• Ensembl ID: ENSNLEG00000005158
• Aliases: None
• Description: None

Sequence

>retro_nleu_2197
ATCAACCAATTCTTCGGGAAAGCGAAACCCAAGGCTCCACTGCCCAGCCTGACTGACTGCATTGACACGGTGGACAGCAG
GGCAGAATCCATTGACAAGATTTCTCGATTGGATGCTGAGCTAGTGAAGTATAAGGATCAGATCAAGAAGATGAGAGAGG
GTCCTGCAAAGAGTATGGTTAAGCAGAAAGCCTCGCGAGTTTTAAAGCAAAAGTGGATGTATGAGCAGCAGGGCAATCTT
GCCCAATAGTCATTCAACATGGAACAAGCCAATTATACCATCCAGTCATTGAAGGATACCAAGACCACGGTTGTTGCTAT
GAAACTGGGAATAAAGGAAATGAAGAAGGCATACAAGCAAGTGAAAATCGACGAGGTTGAGGATTTACGAGACCAGCTAG
AGGATATGATGGAAGATGCAAATGAAATCCAAGAAGCACTGAGTTGCAGTTATGGCACACCAGAACTGGATGAAGATGAC
CTAGAAGCAAAGTTGGATGCACTGGGTGATAAGCTTCTGGCTGATGAAGACAGTTCTTATTTGGATGAGACAGCATCTGC
ATCTGCAGTTCCGGAAGGTGTTCCCACTGATACAAAAAACAAGGATAGAGTTCTGGTGGATGAATTTGGATTGCCACAGA
TCCCTACTTCA

Alignment

ORF - retro_nleu_2197 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.58 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MNRLFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLK
          .N..FGKAKPKAP.PSLTDCI.TVDSRAESIDK.ISRLDAELVKYKDQIKKMREGPAK.MVKQKA.RVLK
Retrocopy INQFFGKAKPKAPLPSLTDCIDTVDSRAESIDK-ISRLDAELVKYKDQIKKMREGPAKSMVKQKASRVLK

Parental  QKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKQVKIDQIEDLQDQLEDMME
          QK.MYEQQ..NLAQ.SFNMEQANYTIQSLKDTKTTV.AMKLG.KEMKKAYKQVKID..EDL.DQLEDMME
Retrocopy QKWMYEQQ-GNLAQ*SFNMEQANYTIQSLKDTKTTVVAMKLGIKEMKKAYKQVKIDEVEDLRDQLEDMME

Parental  DANEIQEALSRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPEGVPTDTKNKDGVLVDE
          DANEIQEALS.SYGTPELDEDDLEA.LDALGD.LLADEDSSYLDE.ASA.A.PEGVPTDTKNKD.VLVDE
Retrocopy DANEIQEALSCSYGTPELDEDDLEAKLDALGDKLLADEDSSYLDETASASAVPEGVPTDTKNKDRVLVDE

Parental  FGLPQIPAS
          FGLPQIP.S
Retrocopy FGLPQIPTS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Nomascus leucogenys was not studied using RNA-Seq expression data.

ChIP-Seq

Nomascus leucogenys was not studied using ChIP-Seq data.

EST

Nomascus leucogenys was not studied using EST data.

TSS

Nomascus leucogenys was not studied using FANTOM5 data.

Lab

retro_nleu_2197 was not experimentally validated.

Homology

Retrocopy orthology:

Nomascus leucogenys does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 37 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000012672	1 retrocopy	retro_chof_2045,
Callithrix jacchus	ENSCJAG00000008104	2 retrocopies	retro_cjac_2868, retro_cjac_4159,
Cavia porcellus	ENSCPOG00000003467	2 retrocopies	retro_cpor_1221, retro_cpor_1306,
Dipodomys ordii	ENSDORG00000006280	2 retrocopies	retro_dord_292, retro_dord_764,
Echinops telfairi	ENSETEG00000001424	1 retrocopy	retro_etel_2126,
Homo sapiens	ENSG00000086065	2 retrocopies	retro_hsap_4822, retro_hsap_494,
Microcebus murinus	ENSMICG00000012113	2 retrocopies	retro_mmur_369, retro_mmur_843,
Myotis lucifugus	ENSMLUG00000011045	1 retrocopy	retro_mluc_954,
Macaca mulatta	ENSMMUG00000020149	1 retrocopy	retro_mmul_2573,
Monodelphis domestica	ENSMODG00000004012	2 retrocopies	retro_mdom_2002, retro_mdom_595,
Mus musculus	ENSMUSG00000028419	1 retrocopy	retro_mmus_1469,
Nomascus leucogenys	ENSNLEG00000005158	2 retrocopies	retro_nleu_2197 , retro_nleu_2420,
Otolemur garnettii	ENSOGAG00000000774	6 retrocopies	retro_ogar_2072, retro_ogar_2190, retro_ogar_2386, retro_ogar_2504, retro_ogar_2509, retro_ogar_916,
Pongo abelii	ENSPPYG00000019137	2 retrocopies	retro_pabe_239, retro_pabe_3750,
Pan troglodytes	ENSPTRG00000020857	2 retrocopies	retro_ptro_3210, retro_ptro_373,
Rattus norvegicus	ENSRNOG00000008672	1 retrocopy	retro_rnor_2614,
Ictidomys tridecemlineatus	ENSSTOG00000026573	1 retrocopy	retro_itri_424,
Tupaia belangeri	ENSTBEG00000003486	5 retrocopies	retro_tbel_1626, retro_tbel_1894, retro_tbel_2407, retro_tbel_3364, retro_tbel_3494,
Tursiops truncatus	ENSTTRG00000010575	1 retrocopy	retro_ttru_338,