RetrogeneDB ID: retro_ocun_1915

Retrocopy location

• Organism: Rabbit (Oryctolagus cuniculus)
• Coordinates: X:11372906..11373346(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSOCUG00000012844
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: MAGOH
• Ensembl ID: ENSOCUG00000001880
• Aliases: None
• Description: mago-nashi homolog, proliferation-associated (Drosophila) [Source:HGNC Symbol;Acc:6815]

Sequence

>retro_ocun_1915
TCTATGGCTAGTGATTTCTACCTGCGCTATTATGTAGGGCACAAAGGCAAGTTTGGACACGAGTTTCTGGAGTTCGAGTT
TCGGCCGGATGGAAAGCTTAGATATGCCAAAATAGTAATTACAAAAATGATGTCATGATCAGAAAAGAGGCTTACGTGCA
CAAGAGTGTAATGGAAGAACTGAAGAGGATTATTGATGACAGTGAAATTACAAAAGAAGATGATGCCTTATGGCCTCCCT
CTGACAGGGTTGGCCGACAGGAGCTTGAAATTGTTATTGGCGATGAACACATTTCTTTTACAACATCAAAAATAGGTTCT
CTTATTGATGTAAATCAGTCAAAGGATCCTGAAGGCCTTCGTGCGTTTTACTATTTGGTACAGGATCTGAAATGTTTAGT
TTTCAATCTCATTGGATTACACTTCAAGATTAAACCAATT

Alignment

ORF - retro_ocun_1915 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 95.27 %
• Parental protein coverage: 99.32 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  AMESDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYAN-NSNYKNDVMIRKEAYVHKSVMEELKRIIDDSE
          .M.SDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYA..NSNYKNDVMIRKEAYVHKSVMEELKRIIDDSE
Retrocopy SMASDFYLRYYVGHKGKFGHEFLEFEFRPDGKLRYAK<NSNYKNDVMIRKEAYVHKSVMEELKRIIDDSE

Parental  ITKEDDALWPPPDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRVFYYLVQDLKCLVFSLIG
          ITKEDDALWPP.DRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLR.FYYLVQDLKCLVF.LIG
Retrocopy ITKEDDALWPPSDRVGRQELEIVIGDEHISFTTSKIGSLIDVNQSKDPEGLRAFYYLVQDLKCLVFNLIG

Parental  LHFKIKPI
          LHFKIKPI
Retrocopy LHFKIKPI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	1.66 RPM	12.09 RPM
SRP017611_kidney	0.51 RPM	21.89 RPM
SRP017611_liver	0.23 RPM	7.78 RPM

ChIP-Seq

Oryctolagus cuniculus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ocun_1915 retrocopy.

TSS

Oryctolagus cuniculus was not studied using FANTOM5 data.

Lab

retro_ocun_1915 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ocun_1915 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 43 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000004538	1 retrocopy	retro_cjac_1902,
Cavia porcellus	ENSCPOG00000011511	1 retrocopy	retro_cpor_338,
Homo sapiens	ENSG00000162385	2 retrocopies	retro_hsap_1803, retro_hsap_3318,
Gorilla gorilla	ENSGGOG00000007594	2 retrocopies	retro_ggor_1303, retro_ggor_1326,
Microcebus murinus	ENSMICG00000006406	2 retrocopies	retro_mmur_70, retro_mmur_781,
Myotis lucifugus	ENSMLUG00000002444	1 retrocopy	retro_mluc_1844,
Nomascus leucogenys	ENSNLEG00000017987	2 retrocopies	retro_nleu_2515, retro_nleu_2682,
Oryctolagus cuniculus	ENSOCUG00000001880	5 retrocopies	retro_ocun_1295, retro_ocun_1720, retro_ocun_1872, retro_ocun_1915 , retro_ocun_1923,
Otolemur garnettii	ENSOGAG00000013328	2 retrocopies	retro_ogar_1954, retro_ogar_24,
Ochotona princeps	ENSOPRG00000009020	1 retrocopy	retro_opri_521,
Pongo abelii	ENSPPYG00000001335	2 retrocopies	retro_pabe_1479, retro_pabe_2733,
Pan troglodytes	ENSPTRG00000000753	1 retrocopy	retro_ptro_2156,
Rattus norvegicus	ENSRNOG00000012778	1 retrocopy	retro_rnor_1168,
Ictidomys tridecemlineatus	ENSSTOG00000001253	3 retrocopies	retro_itri_373, retro_itri_379, retro_itri_932,
Tupaia belangeri	ENSTBEG00000011611	17 retrocopies	retro_tbel_1016, retro_tbel_1120, retro_tbel_1213, retro_tbel_140, retro_tbel_1513, retro_tbel_185, retro_tbel_2030, retro_tbel_2031, retro_tbel_2349, retro_tbel_2355, retro_tbel_2525, retro_tbel_3186, retro_tbel_328, retro_tbel_4512, retro_tbel_4540, retro_tbel_735, retro_tbel_809,