RetrogeneDB ID: retro_pabe_1233

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 15:33755058..33755460(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPS15
• Ensembl ID: ENSPPYG00000009317
• Aliases: None
• Description: 40S ribosomal protein S15 [Source:UniProtKB/Swiss-Prot;Acc:Q5RDI7]

Sequence

>retro_pabe_1233
ATGACAGACGTAGAGCAGAAGAAGTGGACCTTCCGCAAGTTCACTTACCGCGGCGTGGGCCTGGACCAGCTGCTGGACGT
GTCCTACGAGCAGCTTATGCAGCCGTACAGTGCGCGTCGGCAGCAGCGTTTGAACCTGGCCTGGGGCGGAAACAGCACTC
GCCGCTGAAGCGCCTGCGCAAGGCCAAGAAGGAGGTACCGCCCATGGAGAAGCCGGAAGTGGTGAAGACGCACCTGCAGG
ACATAATCATCTTGCCTAAGATGATGGGCAGCATGGTGGGCGTCTACAACGGCAAAACCTTCAGCCAGGTGGAGATCAAG
CTGGAGATGATCGGCCACTACTGGGTGAGTTCTCCATCACCTACAAGCCCGTGAAGCACTGCCGGCCGGCATTGGGGCCA
CC

Alignment

ORF - retro_pabe_1233 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.73 %
• Parental protein coverage: 93.79 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  MAEVEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNR-GLRRKQHSLLKRLRKAKKEAPP
          M..VEQKK..TFRKFTYRGV.LDQLLD.SYEQLMQ.YSAR...RLN..GL.RKQHS.LKRLRKAKKE.PP
Retrocopy MTDVEQKKW-TFRKFTYRGVGLDQLLDVSYEQLMQPYSARRQQRLNL<GLGRKQHSPLKRLRKAKKEVPP

Parental  MEKPEVVKTHLRDMIILPEMVGSMVGVYNGKTFNQVEIKPEMIGHY-LGEFSITYKPVKHGRP-GIGAT
          MEKPEVVKTHL.D.IILP.M.GSMVGVYNGKTF.QVEIK.EMIGHY.LGEFSITYKPVKH.RP.GIGAT
Retrocopy MEKPEVVKTHLQDIIILPKMMGSMVGVYNGKTFSQVEIKLEMIGHY<LGEFSITYKPVKHCRP<GIGAT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	114.62 RPM
SRP007412_cerebellum	0.00 RPM	92.30 RPM
SRP007412_heart	0.00 RPM	64.84 RPM
SRP007412_kidney	0.03 RPM	186.05 RPM
SRP007412_liver	0.03 RPM	133.30 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_1233 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_1233 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_1233 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1484
Gorilla gorilla	retro_ggor_1136

---

Parental genes homology:

Parental genes homology involve 20 parental genes, and 69 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000019718	1 retrocopy	retro_btau_1856,
Callithrix jacchus	ENSCJAG00000005632	13 retrocopies	retro_cjac_143, retro_cjac_151, retro_cjac_1517, retro_cjac_1607, retro_cjac_1672, retro_cjac_1714, retro_cjac_2069, retro_cjac_2236, retro_cjac_2596, retro_cjac_2656, retro_cjac_48, retro_cjac_756, retro_cjac_86,
Cavia porcellus	ENSCPOG00000003968	1 retrocopy	retro_cpor_495,
Dasypus novemcinctus	ENSDNOG00000000706	2 retrocopies	retro_dnov_173, retro_dnov_85,
Echinops telfairi	ENSETEG00000008645	1 retrocopy	retro_etel_2,
Felis catus	ENSFCAG00000010769	1 retrocopy	retro_fcat_1570,
Homo sapiens	ENSG00000115268	4 retrocopies	retro_hsap_1484, retro_hsap_2341, retro_hsap_2650, retro_hsap_530,
Gorilla gorilla	ENSGGOG00000002818	4 retrocopies	retro_ggor_1136, retro_ggor_116, retro_ggor_141, retro_ggor_1851,
Macaca mulatta	ENSMMUG00000003050	2 retrocopies	retro_mmul_2130, retro_mmul_838,
Monodelphis domestica	ENSMODG00000005119	1 retrocopy	retro_mdom_1335,
Mus musculus	ENSMUSG00000063457	8 retrocopies	retro_mmus_1270, retro_mmus_208, retro_mmus_2734, retro_mmus_2786, retro_mmus_3166, retro_mmus_3642, retro_mmus_520, retro_mmus_917,
Nomascus leucogenys	ENSNLEG00000001651	8 retrocopies	retro_nleu_105, retro_nleu_1858, retro_nleu_1922, retro_nleu_2390, retro_nleu_2465, retro_nleu_2559, retro_nleu_461, retro_nleu_544,
Otolemur garnettii	ENSOGAG00000015776	4 retrocopies	retro_ogar_194, retro_ogar_210, retro_ogar_2237, retro_ogar_96,
Pongo abelii	ENSPPYG00000009317	4 retrocopies	retro_pabe_1233 , retro_pabe_2321, retro_pabe_67, retro_pabe_893,
Pan troglodytes	ENSPTRG00000010200	1 retrocopy	retro_ptro_122,
Pteropus vampyrus	ENSPVAG00000003168	2 retrocopies	retro_pvam_382, retro_pvam_926,
Rattus norvegicus	ENSRNOG00000024603	8 retrocopies	retro_rnor_1384, retro_rnor_1711, retro_rnor_1712, retro_rnor_178, retro_rnor_2086, retro_rnor_2114, retro_rnor_2642, retro_rnor_700,
Sarcophilus harrisii	ENSSHAG00000013424	1 retrocopy	retro_shar_632,
Sus scrofa	ENSSSCG00000023248	1 retrocopy	retro_sscr_271,
Ictidomys tridecemlineatus	ENSSTOG00000006423	2 retrocopies	retro_itri_722, retro_itri_939,