RetrogeneDB ID: retro_pabe_3461

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 9:28730339..28730656(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: BOLA3
• Ensembl ID: ENSPPYG00000012285
• Aliases: None
• Description: bolA homolog 3 (E. coli) [Source:HGNC Symbol;Acc:24415]

Sequence

>retro_pabe_3461
TGGAACCCTGCCCTTGTAGCTCCTCTGCCATGCAGGATCTGCAGGCTTCCTTTTCTGCACTGTGTTCATTGGATGTTTGC
CTCCCAGACTGAGGGGAGCTCAAAGGGACCCAAATTCTCAAAGAAAAGTTTTCTGGAGCTACAGCTATCCAAGTCACTGG
CATTTCAGGAGGCTGTAGGTGATGTATAAAATCCAAATCAAACCAGAAGAATTTAAAGAAACGAGAACTGTCCCTCAGCA
CCAGATGATTAATCAGGTACTAAAAAAGGAAAATAAAATGGATGCACAGATTGAGGGTATTTACCTCTGTCCCCAGA

Alignment

ORF - retro_pabe_3461 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 66.06 %
• Parental protein coverage: 96.26 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  WSPAAAAPLLRGIRGLP-LH--HRMFATQTEG-ELRVTQILKEKFPRATAIKVTDISGGCG-AMYEIKIE
          W.PA..APL...I..LP.LH..H.MFA.QTEG.EL..TQILKEKF..ATAI.VT.ISGGC...MY.I.I.
Retrocopy WNPALVAPLPCRICRLPFLHCVHWMFASQTEG<ELKGTQILKEKFSGATAIQVTGISGGCR<VMYKIQIK

Parental  SEEFKEKRTVQQHQMVNQALKEE-IKGMHGLRIFTSVPK
          .EEFKE.RTV.QHQM.NQ.LK.E.IK.MH.LR.FTSVP.
Retrocopy PEEFKETRTVPQHQMINQVLKKE>IKWMHRLRVFTSVPR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	10.56 RPM
SRP007412_cerebellum	0.00 RPM	14.35 RPM
SRP007412_heart	0.00 RPM	21.37 RPM
SRP007412_kidney	0.00 RPM	11.47 RPM
SRP007412_liver	0.09 RPM	5.51 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_3461 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_3461 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_3461 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 10 parental genes, and 22 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000017844	1 retrocopy	retro_cjac_1112,
Homo sapiens	ENSG00000163170	3 retrocopies	retro_hsap_1959, retro_hsap_3383, retro_hsap_4148,
Gorilla gorilla	ENSGGOG00000024505	4 retrocopies	retro_ggor_1423, retro_ggor_1424, retro_ggor_2290, retro_ggor_2786,
Macaca mulatta	ENSMMUG00000015207	2 retrocopies	retro_mmul_1181, retro_mmul_2109,
Mus musculus	ENSMUSG00000045160	1 retrocopy	retro_mmus_1648,
Nomascus leucogenys	ENSNLEG00000000320	4 retrocopies	retro_nleu_1391, retro_nleu_1567, retro_nleu_2604, retro_nleu_971,
Oryctolagus cuniculus	ENSOCUG00000016658	1 retrocopy	retro_ocun_51,
Pongo abelii	ENSPPYG00000012285	2 retrocopies	retro_pabe_1618, retro_pabe_3461 ,
Pan troglodytes	ENSPTRG00000012078	3 retrocopies	retro_ptro_1309, retro_ptro_2299, retro_ptro_2820,
Sorex araneus	ENSSARG00000001754	1 retrocopy	retro_sara_83,