RetrogeneDB ID: retro_ptro_970

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 14:54369927..54370186(-)
• Located in intron of: ENSPTRG00000006375

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: HMGN1
• Ensembl ID: ENSPTRG00000031426
• Aliases: None
• Description: High mobility group nucleosome binding domain 1 [Source:UniProtKB/TrEMBL;Acc:K7DN21]

Sequence

>retro_ptro_970
ATGCCCAAGAGGAAGGTCAGCTCCACTGAACGGGCCACAAAGGAAGAGCCCAAGAGGAGATCGGCACGCTTATCAGCTGA
ACCTGCTCCTGCAAAAGTGGAAACGAAGCTGAGAAAGCAGCAGGAAAGGATAAATCTTCAGACAAAAAAGTGCAAACAAA
AGGGAAAAGGGGAGCAAACGGGGAAAAGTCAGAAGTGGCTAACCAAGAAACTGAAGATTTTCCTGCAGAAAACGAGAAAC
TAAAACTGAGGAGAGCCCC

Alignment

ORF - retro_ptro_970 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 65.56 %
• Parental protein coverage: 87. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MPKRKVSSAEGAAKEEPKRRSARLSAKP-PAKVEAK-PKKAAAKDKSSDKKVQTKGKRGAKGKQAEVANQ
          MPKRKVSS.E.A.KEEPKRRSARLSA.P.PAKVE.K...KAA.KDKSS.................EVANQ
Retrocopy MPKRKVSSTERATKEEPKRRSARLSAEPAPAKVETK<AEKAAGKDKSSXXXXXXXXXXXXXXXXSEVANQ

Parental  ETKEDLPAEN-GETKTEESP
          ET.ED.PAEN..ETKTEESP
Retrocopy ET-EDFPAEN<RETKTEESP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.46 RPM	24.15 RPM
SRP007412_cerebellum	0.93 RPM	17.57 RPM
SRP007412_heart	0.09 RPM	17.72 RPM
SRP007412_kidney	0.37 RPM	44.41 RPM
SRP007412_liver	0.43 RPM	29.20 RPM
SRP007412_testis	0.21 RPM	38.89 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_970 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_970 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_970 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1418
Pongo abelii	retro_pabe_1172

---

Parental genes homology:

Parental genes homology involve 10 parental genes, and 141 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000014100	11 retrocopies	retro_amel_1103, retro_amel_1157, retro_amel_1307, retro_amel_1378, retro_amel_1580, retro_amel_1839, retro_amel_349, retro_amel_352, retro_amel_408, retro_amel_439, retro_amel_670,
Bos taurus	ENSBTAG00000018768	12 retrocopies	retro_btau_1178, retro_btau_1475, retro_btau_1560, retro_btau_1746, retro_btau_1801, retro_btau_388, retro_btau_504, retro_btau_572, retro_btau_607, retro_btau_617, retro_btau_897, retro_btau_928,
Canis familiaris	ENSCAFG00000010045	12 retrocopies	retro_cfam_1056, retro_cfam_1233, retro_cfam_1318, retro_cfam_1392, retro_cfam_1522, retro_cfam_1667, retro_cfam_1904, retro_cfam_2202, retro_cfam_292, retro_cfam_404, retro_cfam_634, retro_cfam_649,
Cavia porcellus	ENSCPOG00000002336	7 retrocopies	retro_cpor_1129, retro_cpor_1389, retro_cpor_334, retro_cpor_349, retro_cpor_4, retro_cpor_884, retro_cpor_949,
Equus caballus	ENSECAG00000019029	5 retrocopies	retro_ecab_1130, retro_ecab_285, retro_ecab_362, retro_ecab_800, retro_ecab_848,
Homo sapiens	ENSG00000205581	7 retrocopies	retro_hsap_1097, retro_hsap_1418, retro_hsap_1581, retro_hsap_1758, retro_hsap_1874, retro_hsap_3370, retro_hsap_762,
Monodelphis domestica	ENSMODG00000020972	5 retrocopies	retro_mdom_1085, retro_mdom_109, retro_mdom_284, retro_mdom_755, retro_mdom_88,
Otolemur garnettii	ENSOGAG00000010329	35 retrocopies	retro_ogar_1062, retro_ogar_1186, retro_ogar_1245, retro_ogar_1304, retro_ogar_1355, retro_ogar_1437, retro_ogar_1527, retro_ogar_1529, retro_ogar_175, retro_ogar_1812, retro_ogar_1901, retro_ogar_1932, retro_ogar_2057, retro_ogar_2311, retro_ogar_2325, retro_ogar_2522, retro_ogar_2523, retro_ogar_266, retro_ogar_2712, retro_ogar_2729, retro_ogar_278, retro_ogar_2913, retro_ogar_2964, retro_ogar_3095, retro_ogar_3133, retro_ogar_3138, retro_ogar_3155, retro_ogar_333, retro_ogar_3354, retro_ogar_370, retro_ogar_393, retro_ogar_657, retro_ogar_699, retro_ogar_723, retro_ogar_958,
Pongo abelii	ENSPPYG00000011426	25 retrocopies	retro_pabe_1066, retro_pabe_1149, retro_pabe_1172, retro_pabe_1190, retro_pabe_123, retro_pabe_1264, retro_pabe_1302, retro_pabe_1504, retro_pabe_1604, retro_pabe_1842, retro_pabe_2152, retro_pabe_2211, retro_pabe_2284, retro_pabe_2380, retro_pabe_251, retro_pabe_2518, retro_pabe_2771, retro_pabe_3086, retro_pabe_3648, retro_pabe_3825, retro_pabe_504, retro_pabe_698, retro_pabe_699, retro_pabe_702, retro_pabe_760,
Pan troglodytes	ENSPTRG00000031426	22 retrocopies	retro_ptro_1256, retro_ptro_1299, retro_ptro_1301, retro_ptro_1454, retro_ptro_1556, retro_ptro_1740, retro_ptro_1821, retro_ptro_1830, retro_ptro_2058, retro_ptro_2290, retro_ptro_2559, retro_ptro_2716, retro_ptro_3119, retro_ptro_3278, retro_ptro_363, retro_ptro_463, retro_ptro_586, retro_ptro_61, retro_ptro_637, retro_ptro_696, retro_ptro_970 , retro_ptro_980,