RetrogeneDB ID: retro_cfam_1786

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 6:17047498..17047955(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCAFG00000000071
• Aliases: None
• Description: None

Sequence

>retro_cfam_1786
ATGAATGTGGGGGTGGCACACAGCGAAGTAAACCCCAACACTCGCGTGATGAATAGCCAGGGCATCTGGCTGGCCTACAT
CATCTTGGTAGGACTGCTGCATGTGGTTCTACTCAGCATCCCCTTCTTCAGCATACCTGTTGTCAGGACCCTGACCAACG
TCATCCATAGTTTGGCTATGTATGTCTTCTTACATACAGTGAAAGGGCCACCCCTTGAGACCCCTGACCAAGGGAAGGCT
CAGCTACTGACACTGGGAACAGATGGACTACGGGCTCCAATTTACCTCTTCCCACCAATTCCTCAGCAGCTCTCCTATTA
TACTCTACCACCTCCTGGCCAGCTTCTACACCAAGTATGATGCTGCTCACTTCATCAACACAGCCTCATTGCTTAGTGTA
CTGCTGCCTAAGTTACCCCAATTCCACGGGGTTCGTCTCTTTGGCATCAACAAATAC

Alignment

ORF - retro_cfam_1786 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 85.16 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MNVGVAHSEVNPNTRVMNSRGIWLAYIILVGLLHVVLLSIPFFSIPVVWTLTNVIHNLAMYVFLHTVK-G
          MNVGVAHSEVNPNTRVMNS.GIWLAYIILVGLLHVVLLSIPFFSIPVV.TLTNVIH.LAMYVFLHTVK.G
Retrocopy MNVGVAHSEVNPNTRVMNSQGIWLAYIILVGLLHVVLLSIPFFSIPVVRTLTNVIHSLAMYVFLHTVK>G

Parental  TPFETPDQGKARLLTHWEQMDYGLQFTSSRKFLSISPIVLY-LLASFYTKYDAAHFIINTASLLSVLLPK
          .P......G......HWEQMDYGLQFTSS..FLS.SPI.LY.LLASFYTKYDAAHF.INTASLLSVLLPK
Retrocopy HPLRPLTKGRLSY*-HWEQMDYGLQFTSSHQFLSSSPIILYHLLASFYTKYDAAHF-INTASLLSVLLPK

Parental  LPQFHGVRLFGINKY
          LPQFHGVRLFGINKY
Retrocopy LPQFHGVRLFGINKY

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.17 RPM	5.46 RPM
SRP017611_brain	0.00 RPM	3.10 RPM
SRP017611_kidney	0.00 RPM	30.77 RPM
SRP017611_liver	0.15 RPM	6.09 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_1786 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_1786 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_1786 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 11 parental genes, and 20 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000000071	8 retrocopies	retro_cfam_1078, retro_cfam_1248, retro_cfam_1512, retro_cfam_1786 , retro_cfam_187, retro_cfam_335, retro_cfam_576, retro_cfam_972,
Choloepus hoffmanni	ENSCHOG00000009601	1 retrocopy	retro_chof_2232,
Erinaceus europaeus	ENSEEUG00000015224	1 retrocopy	retro_eeur_16,
Felis catus	ENSFCAG00000013964	1 retrocopy	retro_fcat_895,
Macropus eugenii	ENSMEUG00000014896	1 retrocopy	retro_meug_767,
Microcebus murinus	ENSMICG00000010920	1 retrocopy	retro_mmur_212,
Myotis lucifugus	ENSMLUG00000003575	1 retrocopy	retro_mluc_901,
Macaca mulatta	ENSMMUG00000006292	1 retrocopy	retro_mmul_2358,
Mustela putorius furo	ENSMPUG00000000911	2 retrocopies	retro_mputfur_452, retro_mputfur_738,
Mus musculus	ENSMUSG00000025353	1 retrocopy	retro_mmus_2646,
Otolemur garnettii	ENSOGAG00000001695	2 retrocopies	retro_ogar_3016, retro_ogar_951,