RetrogeneDB ID: retro_ggor_1696

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 2a:81611081..81611482(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000023594
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: ENSG00000076053
• Ensembl ID: ENSGGOG00000009941
• Aliases: None
• Description: None

Sequence

>retro_ggor_1696
TTTGTGGGCAACCTTGAAACGAAAGTGACCGAGGAGCTCCTTTTCGAGCTTTTCCACCAGGCTGGGCCAGTAATAAAGGT
GAAATTCCAAAAGATAAGGATGGTAAACCAAAGCAGTTTGCGTTTGTGAATTTCAAACATGAAGTATCTGTTCCTTATGC
AATGAATCTACTTAATGGAATCAAACTTTACGGAAGGCCTATCAAAATTCAATTTAGATCAGGAAGTAGTCATGCCTCGC
AAGATGTCAGTTTGCCATATCCCCAACATCATGTTGGAAATTCAAGCCCTACCTCCACATCTCCTAGCAGGTACGAAAGG
ACTAGGGATAACATGACTTCATCAGCACAGATAATTCAGAGATCTTTCTCTTCTCCAGAAAATTTTCAGAGACAAGCAGT
G

Alignment

ORF - retro_ggor_1696 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 97.04 %
• Parental protein coverage: 91.78 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  FVGNLETKVTEELLFELFHQAGPVIKVK-IPKDKDGKPKQFAFVNFKHEVSVPYAMNLLNGIKLYGRPIK
          FVGNLETKVTEELLFELFHQAGPVIKVK.IPKDKDGKPKQFAFVNFKHEVSVPYAMNLLNGIKLYGRPIK
Retrocopy FVGNLETKVTEELLFELFHQAGPVIKVK<IPKDKDGKPKQFAFVNFKHEVSVPYAMNLLNGIKLYGRPIK

Parental  IQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPSRYERTMDNMTSSAQIIQRSFSSPENFQRQAV
          IQFRSGSSHA.QDVSL.YPQHHVGNSSPTSTSPSRYERT.DNMTSSAQIIQRSFSSPENFQRQAV
Retrocopy IQFRSGSSHASQDVSLPYPQHHVGNSSPTSTSPSRYERTRDNMTSSAQIIQRSFSSPENFQRQAV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	0.91 RPM
SRP007412_cerebellum	0.24 RPM	1.34 RPM
SRP007412_heart	0.16 RPM	0.72 RPM
SRP007412_kidney	0.49 RPM	1.80 RPM
SRP007412_liver	0.42 RPM	2.48 RPM
SRP007412_testis	1.35 RPM	8.29 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1696 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1696 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2283
Pan troglodytes	retro_ptro_1617

---

Parental genes homology:

Parental genes homology involve 17 parental genes, and 20 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000013514	1 retrocopy	retro_cfam_1021,
Choloepus hoffmanni	ENSCHOG00000012747	1 retrocopy	retro_chof_570,
Homo sapiens	ENSG00000076053	1 retrocopy	retro_hsap_2283,
Gorilla gorilla	ENSGGOG00000004761	1 retrocopy	retro_ggor_1056,
Gorilla gorilla	ENSGGOG00000009941	1 retrocopy	retro_ggor_1696 ,
Loxodonta africana	ENSLAFG00000012444	1 retrocopy	retro_lafr_892,
Myotis lucifugus	ENSMLUG00000023234	2 retrocopies	retro_mluc_1555, retro_mluc_587,
Monodelphis domestica	ENSMODG00000013918	1 retrocopy	retro_mdom_535,
Mus musculus	ENSMUSG00000042396	1 retrocopy	retro_mmus_2436,
Nomascus leucogenys	ENSNLEG00000007323	1 retrocopy	retro_nleu_409,
Oryctolagus cuniculus	ENSOCUG00000003342	1 retrocopy	retro_ocun_924,
Otolemur garnettii	ENSOGAG00000016857	1 retrocopy	retro_ogar_3103,
Pongo abelii	ENSPPYG00000003894	1 retrocopy	retro_pabe_1669,
Pan troglodytes	ENSPTRG00000004305	1 retrocopy	retro_ptro_1617,
Ictidomys tridecemlineatus	ENSSTOG00000012459	1 retrocopy	retro_itri_889,
Tursiops truncatus	ENSTTRG00000001515	3 retrocopies	retro_ttru_1316, retro_ttru_1441, retro_ttru_478,
Vicugna pacos	ENSVPAG00000006300	1 retrocopy	retro_vpac_311,