RetrogeneDB ID: retro_ocun_1810

Retrocopy location

• Organism: Rabbit (Oryctolagus cuniculus)
• Coordinates: GL018979:226140..226849(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: VTA1
• Ensembl ID: ENSOCUG00000002554
• Aliases: None
• Description: Vps20-associated 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:20954]

Sequence

>retro_ocun_1810
AAGAAACAGTTGGGTGATAATGAAGCTATTACCCAAGGAGCAGTTGGTTTTGCCCATTTGGGGAATTATGATTTGAAAAT
GTTTATATATGCAGACAATGAACATTGTGCTGGAGATTTCACAAAAACATGATCAAGTTCTTCTATACTGCAAGTCTTTT
AATAGATGTCATAACTGTGTTTGACATAACACTGATGAAAATGTGAAACACAGAAAGTATGCAAGGTGGAAGGCAACATA
TATACATAATTGCCTAAAGAATGAGGAGACTCCTCAAGCAGGCCCTATTGCAATTGAGGAAGATACTGATGGTGAAGAAA
ATGAAGATGCTGTAGTAGCATCTCTGCCCATTCAACACACCTCAGCCATCATCATCTTCAGCAGTTGTCCCAGGCAGCAT
GCCATCAGACAGCTATAGTTGAATACAGATTCCTCTGGGTGCACATGCTCTAGCCTACACACCAGCAAAAGTGCCTCATA
GCATGGGTGTAACAAAGAATACCATCCAACCTACTCTATAGACTATTCCAGCCATTGATTCTGCATGTTTCAGTACAGTT
TCCCAAGGCCATATCCACCTCACCCCTGAGTACGTTGTGAGAGCTCAGAAATATTGCAAATACACTTCCAGTGCTTTGCA
ATATGAAGATGTAAGCACTGCCTTCAGAATATACAGAAAGACCTCAAGTTACCAATGACTAACAGAGAA

Alignment

ORF - retro_ocun_1810 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.42 %
• Parental protein coverage: 77.2 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  KKQLGDNEAITQEIVGSAHLENYALKMFLYADNEDRAG-RFHKNMIKSFYTASLLIDVITVFG-ELTDEN
          KKQLGDNEAITQ..VG.AHL.NY.LKMF.YADNE..AG.RFHKNMIK.FYTASLLIDVITVF....TDEN
Retrocopy KKQLGDNEAITQGAVGFAHLGNYDLKMFIYADNEHCAG<RFHKNMIKFFYTASLLIDVITVFD<HNTDEN

Parental  VKHRKYARWKATYIHNCLKNGETPQAGPVGIEEDNDGEENEDAGVASLPTQ-PPQPSSSSAFDPGSMPSG
          VKHRKYARWKATYIHNCLKN.ETPQAGP..IEED.DGEENEDA.VASLP.Q..PQPSSSSA..PGSMPS.
Retrocopy VKHRKYARWKATYIHNCLKNEETPQAGPIAIEEDTDGEENEDAVVASLPIQ>TPQPSSSSAVVPGSMPSD

Parental  SYSGIQIPPGAHAPANTPAEVPHGTGVTSNTIQPAPQTIPAIDPALFSTVSQGDIRLTPEDFARAQKYCK
          SYS.IQIP.GAHA.A.TPA.VPH..GVT.NTIQP...TIPAID.A.FSTVSQG.I.LTPE...RAQKYCK
Retrocopy SYS*IQIPLGAHALAYTPAKVPHSMGVTKNTIQPTL*TIPAIDSACFSTVSQGHIHLTPEYVVRAQKYCK

Parental  YAGSALQYEDVSTA-VQNLQKALKLLTTGRE
          Y..SALQYEDVSTA..QN.QK.LKL..T.RE
Retrocopy YTSSALQYEDVSTA<LQNIQKDLKLPMTNRE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	16.39 RPM
SRP017611_kidney	0.00 RPM	12.26 RPM
SRP017611_liver	0.00 RPM	4.08 RPM

ChIP-Seq

Oryctolagus cuniculus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ocun_1810 retrocopy.

TSS

Oryctolagus cuniculus was not studied using FANTOM5 data.

Lab

retro_ocun_1810 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ocun_1810 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 9 parental genes, and 19 retrocopies.

Species	Parental gene accession	Retrocopies number
Homo sapiens	ENSG00000009844	1 retrocopy	retro_hsap_4088,
Gorilla gorilla	ENSGGOG00000015524	1 retrocopy	retro_ggor_2742,
Microcebus murinus	ENSMICG00000004420	2 retrocopies	retro_mmur_1290, retro_mmur_290,
Macaca mulatta	ENSMMUG00000023012	1 retrocopy	retro_mmul_751,
Nomascus leucogenys	ENSNLEG00000015053	1 retrocopy	retro_nleu_1911,
Oryctolagus cuniculus	ENSOCUG00000002554	10 retrocopies	retro_ocun_1543, retro_ocun_1689, retro_ocun_1790, retro_ocun_1810 , retro_ocun_1821, retro_ocun_1832, retro_ocun_1848, retro_ocun_1853, retro_ocun_1864, retro_ocun_965,
Pan troglodytes	ENSPTRG00000018662	1 retrocopy	retro_ptro_2773,
Rattus norvegicus	ENSRNOG00000011540	1 retrocopy	retro_rnor_799,
Tursiops truncatus	ENSTTRG00000014998	1 retrocopy	retro_ttru_1825,