RetrogeneDB ID: retro_ogar_2582

Retrocopy location

• Organism: Bushbaby (Otolemur garnettii)
• Coordinates: GL873636.1:3493340..3494315(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: AKR1A1
• Ensembl ID: ENSOGAG00000007175
• Aliases: None
• Description: aldo-keto reductase family 1, member A1 (aldehyde reductase) [Source:HGNC Symbol;Acc:380]

Sequence

>retro_ogar_2582
ATGGCAGTTTCCTGTGTCCTCCTGCACACTGGGCAAAATATGCCCCTGATTGGTCTGGGCACCTGGAAGAGTCAGCCTGG
CCAGGTAAAAGCAGCTGTTAAGTATGCCCTTAGTGTAGGCTACCACCACATTGACTGGGCTGCTATCTATGGCAATGAGA
CTGAGATTGGGGAGGCCCTGAAGGAGGATGTGGGACCAGGCAAGGCAGTGCCTTGGGAGGAGCTGTTCGTGACGTCCAAG
CTATGGAACACCAAGCACCACCCTGAGGATGTGGAGCTTGCCCTCTGGAAGACACCTGCTGACATCCAACTGGAGTATCT
GGACCTGTACCTGATGCACTGGCCTTATGCCTTTGAGAGGGGAGATAACCCCTTCACCAAGAATACTGATGGGACCATAT
GCTATGATTCTACCCACTACAAGGAGATCTGGAAGGCTCTGGTGGCACTTGTGGCTAAGGGGCTGGTATGGGCACTGGGC
CTGTCCAACTTCAACAGTCGGCAGATTGATGATATACTCAGCGTAGCTTCTGTGCACCCAGCTGTCTTACAGGTGGAATG
CCACCCATTCTTGGCTCAGAATGAGCTAATTGCCATCTGCCAAGCACGGGGCCTGGAGGCGACCACTTATAGCCCTTTGG
GCTCCTCGGATAGTGCTTGGCGTGATCCTGATGTGTCTGTCCTGCTTGAGGAACCAGTGGTCCTGGCACTGGCTGAAAAG
CATGGCTGATCTCCAGCTCAGATCTTGCTCAGGTGCCAAGTCCAGTGGAATGTGATTTGCATCCCCAAAAGGGTCACTCC
TTCTCGTATCCTTCAGAATATCCAGGTGTTTGACTTCACCTTCAGCCCAGAAGAATTGAAGCAGCCAGATGCCCTGAACA
AAAATTGGCGATATACTGTGCCCATGCTTATGGTGGATGGGAAGAGAGTCCTAAGGGATGCAGGACACCCCCTGTACCCC
TTTAATGACCCATAC

Alignment

ORF - retro_ogar_2582 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 90.46 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAVSCVLLHTGQKMPLIGLGTWKSQPGQVKAAVKYALSVGYRHIDCAAIYGNETEIGEALKEDVGPGKAV
          MAVSCVLLHTGQ.MPLIGLGTWKSQPGQVKAAVKYALSVGY.HID.AAIYGNETEIGEALKEDVGPGKAV
Retrocopy MAVSCVLLHTGQNMPLIGLGTWKSQPGQVKAAVKYALSVGYHHIDWAAIYGNETEIGEALKEDVGPGKAV

Parental  PREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTIRYDSTHY
          P.EELFVTSKLWNTKHHPEDVE.AL.KT.AD.QLEYLDLYLMHWPYAFERGDNPF.KN.DGTI.YDSTHY
Retrocopy PWEELFVTSKLWNTKHHPEDVELALWKTPADIQLEYLDLYLMHWPYAFERGDNPFTKNTDGTICYDSTHY

Parental  KETWKALEALVAKGLVRALGLSNFNSRQIDDILSVASVRPAVLQVECHPFLAQNELIAVCQARGLEVTAY
          KE.WKAL.ALVAKGLV.ALGLSNFNSRQIDDILSVASV.PAVLQVECHPFLAQNELIA.CQARGLE.T.Y
Retrocopy KEIWKALVALVAKGLVWALGLSNFNSRQIDDILSVASVHPAVLQVECHPFLAQNELIAICQARGLEATTY

Parental  SPLGSSDRAWRDPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSVTPSRILQNIQVFDFT
          SPLGSSD.AWRDPD..VLLEEPVVLALAEKHG.SPAQILLR.QVQ..VICIPK.VTPSRILQNIQVFDFT
Retrocopy SPLGSSDSAWRDPDVSVLLEEPVVLALAEKHG*SPAQILLRCQVQWNVICIPKRVTPSRILQNIQVFDFT

Parental  FSPEEMKQLDALNKNWRYIVPMLTVDGKRVPRDAGHPLYPFNDPY
          FSPEE.KQ.DALNKNWRY.VPML.VDGKRV.RDAGHPLYPFNDPY
Retrocopy FSPEELKQPDALNKNWRYTVPMLMVDGKRVLRDAGHPLYPFNDPY

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Otolemur garnettii was not studied using RNA-Seq expression data.

ChIP-Seq

Otolemur garnettii was not studied using ChIP-Seq data.

EST

Otolemur garnettii was not studied using EST data.

TSS

Otolemur garnettii was not studied using FANTOM5 data.

Lab

retro_ogar_2582 was not experimentally validated.

Homology

Retrocopy orthology:

Otolemur garnettii does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 8 parental genes, and 11 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000004549	1 retrocopy	retro_cfam_558,
Callithrix jacchus	ENSCJAG00000013633	2 retrocopies	retro_cjac_3093, retro_cjac_3334,
Echinops telfairi	ENSETEG00000006450	1 retrocopy	retro_etel_1106,
Macropus eugenii	ENSMEUG00000007370	1 retrocopy	retro_meug_1,
Otolemur garnettii	ENSOGAG00000007175	2 retrocopies	retro_ogar_1522, retro_ogar_2582 ,
Otolemur garnettii	ENSOGAG00000016156	2 retrocopies	retro_ogar_1282, retro_ogar_808,
Tarsius syrichta	ENSTSYG00000005301	1 retrocopy	retro_tsyr_1409,
Tursiops truncatus	ENSTTRG00000012180	1 retrocopy	retro_ttru_751,