RetrogeneDB ID: retro_cfam_1577

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 35:1345229..1345516(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSCAFG00000009194
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: DYNLRB1
• Ensembl ID: ENSCAFG00000007547
• Aliases: None
• Description: Canis lupus familiaris dynein, light chain, roadblock-type 1 (DYNLRB1), mRNA. [Source:RefSeq mRNA;Acc:NM_001252419]

Sequence

>retro_cfam_1577
ATGGCAGAGGCTGAGGAGACGCTGAAGGACTTCAGAGCCAGAAGGGAGTGCAGGGCATCATCGTGGGGAACACAGAAGGC
ATTGCCATCAAGAGCGCCATGGACAATCCCACTACCACACAGTATGCCAACCTCATGCACGACTCCATCTTGAAGGCCCG
GAGCACCGTCCATGAAGTTGACCCACAGAATGACCTCACCTTTCTTCGAATTCACTCCAAGAAAATTGAAATCATGGTTG
CACCAGATAAAGACTACTTCCCGATTGTGATTCAGAATCCAACTGAA

Alignment

ORF - retro_cfam_1577 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 86.6 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MAEVEETLKR-LQSQKGVQGIIVVNTEGIPIKSTMDNPTTTQYANLMHNFILKARSTVREIDPQNDLTFL
          MAE.EETLK..LQSQKGVQGIIV.NTEGI.IKS.MDNPTTTQYANLMH..ILKARSTV.E.DPQNDLTFL
Retrocopy MAEAEETLKD<LQSQKGVQGIIVGNTEGIAIKSAMDNPTTTQYANLMHDSILKARSTVHEVDPQNDLTFL

Parental  RIRSKKNEIMVAPDKDYFLIVIQNPTE
          RI.SKK.EIMVAPDKDYF.IVIQNPTE
Retrocopy RIHSKKIEIMVAPDKDYFPIVIQNPTE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.00 RPM	100.04 RPM
SRP017611_brain	0.00 RPM	64.31 RPM
SRP017611_kidney	0.00 RPM	62.93 RPM
SRP017611_liver	0.00 RPM	16.75 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_1577 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_1577 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_1577 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 42 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000009179	1 retrocopy	retro_amel_1111,
Canis familiaris	ENSCAFG00000007547	6 retrocopies	retro_cfam_1161, retro_cfam_1294, retro_cfam_1577 , retro_cfam_1601, retro_cfam_1782, retro_cfam_930,
Canis familiaris	ENSCAFG00000020024	1 retrocopy	retro_cfam_575,
Callithrix jacchus	ENSCJAG00000018199	10 retrocopies	retro_cjac_1010, retro_cjac_1172, retro_cjac_1274, retro_cjac_1539, retro_cjac_2071, retro_cjac_2902, retro_cjac_3185, retro_cjac_3215, retro_cjac_3260, retro_cjac_882,
Equus caballus	ENSECAG00000008404	2 retrocopies	retro_ecab_102, retro_ecab_553,
Echinops telfairi	ENSETEG00000018637	2 retrocopies	retro_etel_218, retro_etel_699,
Felis catus	ENSFCAG00000002304	1 retrocopy	retro_fcat_1228,
Homo sapiens	ENSG00000125971	2 retrocopies	retro_hsap_1946, retro_hsap_948,
Gorilla gorilla	ENSGGOG00000023900	1 retrocopy	retro_ggor_764,
Loxodonta africana	ENSLAFG00000029820	2 retrocopies	retro_lafr_722, retro_lafr_852,
Microcebus murinus	ENSMICG00000003253	1 retrocopy	retro_mmur_263,
Myotis lucifugus	ENSMLUG00000004820	3 retrocopies	retro_mluc_1200, retro_mluc_1763, retro_mluc_443,
Macaca mulatta	ENSMMUG00000031253	1 retrocopy	retro_mmul_779,
Nomascus leucogenys	ENSNLEG00000010082	2 retrocopies	retro_nleu_1478, retro_nleu_2456,
Oryctolagus cuniculus	ENSOCUG00000021027	2 retrocopies	retro_ocun_351, retro_ocun_745,
Otolemur garnettii	ENSOGAG00000016802	2 retrocopies	retro_ogar_7, retro_ogar_983,
Pongo abelii	ENSPPYG00000010937	1 retrocopy	retro_pabe_810,
Pan troglodytes	ENSPTRG00000013416	1 retrocopy	retro_ptro_655,
Ictidomys tridecemlineatus	ENSSTOG00000014820	1 retrocopy	retro_itri_1244,