RetrogeneDB ID: retro_chof_1343

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_268429:529..1191(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSCHOG00000006391
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: SPIN1
• Ensembl ID: ENSCHOG00000006983
• Aliases: None
• Description: spindlin 1 [Source:HGNC Symbol;Acc:11243]

Sequence

>retro_chof_1343
AGCAGACCCACCAACCAGGGTCGAAGGAACATCGTGGGCTGCAGAATTCAGCACATATGGAAAGAGGGATATGAACCTCT
AACACAGTGGAAGGGAACCGTTTTTGGATCAAGTACCTGTAAATCCCTCTCTGTATCTTACCGAATATGATGTATTTGAC
TGTGTTTATGGACTGGAACTTCACAGAGATGAAAGCGTGTTATCACCTGAAGTCCTTCCTAATAGAATTGCATCATCTAG
AATCAGTGACACACACTTAGCAGAAATCATGATTGGCAAAGCAGTGGAACATATTTTTGAGAGAGAAGAGGGTTCCAAGA
ATGAATGGAGGGGGATGGTCTTAGGTCAGGCATCTGTTATGAACCACATGGTTTTACATTAGGTATGAGAAAGGTCCTGT
ACTGTATATGTACCAGCTCTTAAATGATTAGAAGGACAGTGACCTTCACATCCTTCAAGATTGCAGTGATACCCCTCCAG
CAGAGAGGGAACCAGGAGAAGTTGTAGACAGCCCAGTAGGCAAATAGTTTGAATATGCTAAAGATGATGGCTCCAGGAGA
ACTGGTATGGTCATTCATCAGGTAGAAACAAAGCCCTCTGTATATTTCATCAAATTTGATGGTGATTTCCATATCTATTT
CTATGATTTGGTAAAAACATCT

Alignment

ORF - retro_chof_1343 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 72.07 %
• Parental protein coverage: 83.97 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  SKPVSQPRRNIVGCRIQHGWKEGNGPVTQWKGTV-LDQVPVNPSLYLIKYDGFDCVYGLELNKDERVSAL
          S.P..Q.RRNIVGCRIQH.WKEG..P.TQWKGTV.LDQVPVNPSLYL..YD.FDCVYGLEL..DE.V...
Retrocopy SRPTNQGRRNIVGCRIQHIWKEGYEPLTQWKGTV>LDQVPVNPSLYLTEYDVFDCVYGLELHRDESVLSP

Parental  EVLPDRVATSRIRDAHIADAMIGKAVQHMFETEDGSKDEWIGKMKARAPIGN-TWFYITYEKDPVLYMSQ
          EVLP.R.A.SRI.D.H.A..MIGKAV.H.FE.E.GSK.EW.G.....A...N.TWFYI.YEK.PVLYM.Q
Retrocopy EVLPNRIASSRISDTHLAEIMIGKAVEHIFEREEGSKNEWRGMVLGQASVMN>TWFYIRYEKGPVLYMYQ

Parental  LLDDYKEGDLRIMPDSNDSPPAEREPGEVVDSLVGKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDD
          LL.D.K..DL.I..D..D.PPAEREPGEVVDS.VGK..EYAK.DGS.RTGMVIHQVE.KPSVYFIKFD.D
Retrocopy LLND*KDSDLHILQDCSDTPPAEREPGEVVDSPVGK*FEYAKDDGSRRTGMVIHQVETKPSVYFIKFDGD

Parental  FHIYVYDLVKTS
          FHIY.YDLVKTS
Retrocopy FHIYFYDLVKTS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_1343 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 23 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000003301	4 retrocopies	retro_amel_1831, retro_amel_1879, retro_amel_38, retro_amel_41,
Bos taurus	ENSBTAG00000003044	4 retrocopies	retro_btau_1678, retro_btau_1841, retro_btau_187, retro_btau_553,
Canis familiaris	ENSCAFG00000002208	3 retrocopies	retro_cfam_153, retro_cfam_2095, retro_cfam_59,
Choloepus hoffmanni	ENSCHOG00000006983	2 retrocopies	retro_chof_1343 , retro_chof_1852,
Callithrix jacchus	ENSCJAG00000017452	1 retrocopy	retro_cjac_227,
Cavia porcellus	ENSCPOG00000000743	1 retrocopy	retro_cpor_123,
Echinops telfairi	ENSETEG00000013719	1 retrocopy	retro_etel_28,
Felis catus	ENSFCAG00000007197	2 retrocopies	retro_fcat_32, retro_fcat_70,
Homo sapiens	ENSG00000106723	1 retrocopy	retro_hsap_64,
Loxodonta africana	ENSLAFG00000027497	2 retrocopies	retro_lafr_18, retro_lafr_58,
Microcebus murinus	ENSMICG00000014510	1 retrocopy	retro_mmur_8,
Myotis lucifugus	ENSMLUG00000008516	2 retrocopies	retro_mluc_132, retro_mluc_1626,
Mustela putorius furo	ENSMPUG00000008585	1 retrocopy	retro_mputfur_139,
Mus musculus	ENSMUSG00000021395	3 retrocopies	retro_mmus_112, retro_mmus_16, retro_mmus_3351,
Oryctolagus cuniculus	ENSOCUG00000011880	1 retrocopy	retro_ocun_63,
Otolemur garnettii	ENSOGAG00000002166	2 retrocopies	retro_ogar_2327, retro_ogar_9,
Procavia capensis	ENSPCAG00000015800	1 retrocopy	retro_pcap_14,
Pongo abelii	ENSPPYG00000019355	1 retrocopy	retro_pabe_33,
Pan troglodytes	ENSPTRG00000021088	2 retrocopies	retro_ptro_116, retro_ptro_95,
Pteropus vampyrus	ENSPVAG00000013391	3 retrocopies	retro_pvam_2, retro_pvam_22, retro_pvam_858,
Rattus norvegicus	ENSRNOG00000011119	4 retrocopies	retro_rnor_1483, retro_rnor_1531, retro_rnor_281, retro_rnor_2818,
Ictidomys tridecemlineatus	ENSSTOG00000029107	1 retrocopy	retro_itri_136,
Tursiops truncatus	ENSTTRG00000005602	6 retrocopies	retro_ttru_1061, retro_ttru_13, retro_ttru_1452, retro_ttru_1506, retro_ttru_1669, retro_ttru_1698,